Research Group: Developmental BioEngineering (DBE)

2013

Spitters, T.W.G.M. and Leijten, J.C.H. and Deus, F.D. and Costa, I.B.F. and Apeldoorn van, A.A. and Blitterswijk van, C.A. and Karperien, H.B.J. (2013) A dual flow bioreactor with controlled mechanical stimulation for cartilage tissue engineering. Tissue Engineering. Part C Methods . ISSN 1937-3384

Wennink, Johannes Wilhelmus Hendrikus (2013) Biodegradable hydrogels by physical and enzymatic crosslinking of biomacromolecules. thesis.

Yang, B. and Tang, Q. and Post, J.N. and Zhou, H. and Huang, X.-B. and Zhang, X.-D. and Wang, Qin and Sun, Y.-M. and Fan, F.-Y. (2013) Effect of radiation on the Notch signaling pathway in osteoblasts. International journal of molecular medicine, 31 (3). 698 - 706. ISSN 1107-3756

Masaeli, E. and Morshed, M. and Hossein Nasr-Esfahani, M. and Sadri, S. and Hilderink, J. and Apeldoorn van, A.A. and Blitterswijk van, C.A. and Moroni, L. (2013) Fabrication, Characterization and Cellular Compatibility of Poly(Hydroxy Alkanoate) Composite Nanofibrous Scaffolds for Nerve Tissue Engineering. PLoS ONE, 8 (2). e57157 - . ISSN 1932-6203

Ling, W. and Leijten, J.C.H. and Post, J.N. and Karperien, H.B.J. (2013) Fibroblast growth factor-1 is a mesenchymal stromal cell secreted factor stimulating proliferation of Osteoarthritic chondrocytes. In: World Congress on Osteoarthritis, OARSI 2013, Philadelphia, PA, USA, April 18-21, 2013, April 18-21, 2013, Philadelphia.

Ma, B. and Leijten, J.C.H. and Wu, L. and Kip, M. and Blitterswijk van, C.A. and Post, J.N. and Karperien, H.B.J. (2013) Gene expression profiling of dedifferentiated human articular chondrocytes in monolayer culture. Osteoarthritis and cartilage, 21 (4). 599 - 603. ISSN 1063-4584

Higuera Sierra, G.A. and Hendriks, J.A. and Dalum van, J. and Wu, L. and Schotel, R. and Moreira Teixeira, L.S. and Doel van den, M. and Leijten, J.C.H. and Riesle, J. and Karperien, H.B.J. and Blitterswijk van, C.A. and Moroni, L. (2013) In vivo screening of extracellular matrix components produced under multiple experimental conditions implanted in one animal. Integrative Biology . ISSN 1757-9694

Karperien, H.B.J. (2013) Injecteerbare pleister op komst. RondReuma, 2013 (maart). 4 - 6. ISSN 1566-6018

Doorn, J. and Roberts, S.J. and Hilderink, J. and Groen, N. and Apeldoorn van, A.A. and Blitterswijk van, C.A. and Schrooten, J. and Boer de, J. (2013) Insulin-like-growth-factor-I enhances proliferation and differentiation of human mesenchymal stromal cells in vitro. Tissue engineering. Part A . ISSN 1937-3341

Buitinga, M. and Truckenmüller, R.K. and Engelse, M.A. and Moroni, L. and Hoopen ten, H.W.M. and Blitterswijk van, C.A. and Koning de, E.J.P. and Apeldoorn van, A.A. and Karperien, H.B.J. (2013) Microwell Scaffolds for the Extrahepatic Transplantation of Islets of Langerhans. PLoS ONE, 8 . 1 - 11. ISSN 1932-6203

Liu, J. and Hilderink, J. and Groothuis, T.A.M. and Otto, C. and Blitterswijk van, C.A. and Boer de, J. (2013) Monitoring nutrient transport in tissue-engineered grafts. Journal of tissue engineering and regenerative medicine . ISSN 1932-6254

Georgi, N. (2013) Multiple choice: leveraging instructive culture models to improve cartilage tissue engineering. thesis.

Silva, J.M. and Georgi, N. and Costa, R. and Sher, P. and Reis, R.L. and Blitterswijk van, C.A. and Karperien, H.B.J. and Mano, J.F. (2013) Nanostructured 3D Constructs Based on Chitosan and Chondroitin Sulphate Multilayers for Cartilage Tissue Engineering. PLoS ONE, 8 (2). e55451. ISSN 1932-6203

Breteler ten, M.R. and Feijen, J. and Dijkstra, P.J. and Signori, F. (2013) Synthesis and thermal properties of hetero-bifunctional PLA oligomers and their stereocomplexes. Reactive and functional polymers, 73 (1). 30 - 38. ISSN 1381-5148

Ma, B. and Zhong, L. and Blitterswijk van, C.A. and Post, J.N. and Karperien, H.B.J. (2013) TCF4 is a pro-catabolic and apoptotic factor in human articular chondrocytes by potentiating NF-κB signaling. Journal of biological chemistry . ISSN 1083-351X

Portalska, K.K. and Groen, N. and Krenning, G. and Georgi, N. and Mentink, A. and Harmsen, M.C. and Blitterswijk van, C.A. and Boer de, J. (2013) The effect of donor variation and senescence on endothelial differentiation of human mesenchymal stromal cells. Tissue engineering. Part A . ISSN 1937-3341

Ma, B. and Landman, E.B.M. and Miclea, R.L. and Wit, J.M. and Robanus-Maandag, E.C. and Post, J.N. and Karperien, H.B.J. (2013) WNT Signaling and Cartilage: Of Mice and Men. Calcified tissue international, 92 (5). 399 - 411. ISSN 0171-967X

2012

Berenschot, Erwin J.W. and Burouni, Narges and Schurink, B. and Honschoten van, Joost W. and Sanders, Remco G.P. and Truckenmuller, Roman and Jansen, Henri V. and Elwenspoek, Miko C. and Apeldoorn van, Aart A. and Tas, Niels R. (2012) 3D Nanofabrication of Fluidic Components by Corner Lithography. Small, 8 (24). pp. 3823-3831. ISSN 1613-6810

Ma, B. and Blitterswijk van, C.A. and Karperien, H.B.J. (2012) A Wnt/β-catenin negative feedback loop inhibits interleukin-1–induced matrix metalloproteinase expression in human articular chondrocytes. Arthritis & rheumatism, 64 (8). 2589 - 2600. ISSN 1529-0131

Duyvenvoorde, H.A. and Ruivenkamp, C.A. and Mul, D. and Oostdijk, W. and Karperien, H.B.J. and Losekoot, M. and Pereira, A.M. and Kant, S.G. and Wit, J.M. (2012) A quest for copy number variations causing extreme tall stature. In: European Society for Pediatric Endocrinology.

Leijten, J.C.H. and Georgi, N. and Wu, L. and Blitterswijk van, C.A. and Karperien, H.B.J. (2012) Cell sources for articular cartilage repair strategies: shifting from mono-cultures to co-cultures. Tissue Engineering. Part B, 19 (1). pp. 31-40. ISSN 1937-3368

Duyvenvoorde, H.A. and Lui, J. and Kant, S.G. and Oostdijk, W. and Gijsbers, A.C.J. and Karperien, H.B.J. and Walenkamp, M.J.E. and Noordam, C. and Voorhoeve, P.G. and Mericq, V. and Gool van, S.A. and Breuning, M.H. and Losekoot, M. and Baron, J. and Ruivenkamp, C.A. and Wit, J.M. (2012) Copy number variations in patients with idiopathic short stature [Poster]. In: European Society for Pediatric Endocrinology.

Moreira Teixeira, L.S. and Feijen, J. and Blitterswijk van, C.A. and Dijkstra, P.J. and Karperien, H.B.J. (2012) Enzyme-catalyzed crosslinkable hydrogels: Emerging strategies for tissue engineering. Biomaterials, 33 (5). 1281 - 1290. ISSN 0142-9612

Gool van, S.A. and Emons, J.A.M. and Leijten, J.C.H. and Decker, E. and Sticht, C. and Houwelingen van, J.C. and Goeman, J.J. and Kleijburg, C. and Scherjon, S. and Gretz, N. and Wit, J.M. and Rappold, G. and Post, J.N. and Karperien, H.B.J. (2012) Fetal Mesenchymal Stromal Cells Differentiating towards Chondrocytes Acquire a Gene Expression Profile Resembling Human Growth Plate Cartilage. PLoS ONE, 7 (11). 1 - 11. ISSN 1932-6203

Leijten, J.C.H. and Emons, J. and Sticht, C. and Gool van, S. and Decker, E. and Uitterlinden, A. and Rappold, G. and Hofman, A. and Rivadeneira, F. and Scherjon, S. and Wit, J.M. and Meurs van, J. and Blitterswijk van, C.A. and Karperien, H.B.J. (2012) Gremlin 1, Frizzled-related protein, and Dkk-1 are key regulators of human articular cartilage homeostasis. Arthritis & rheumatism, 64 (10). 3302 - 3312. ISSN 1529-0131

Leijten, J.C.H. and Emons, J. and Sticht, C. and Gool van, S. and Decker, E. and Uitterlinden, A. and Rappold, G. and Hofman, A. and Rivadeneira, F. and Scherjon, S. and Wit, J.M. and Meurs van, J. and Blitterswijk van, C.A. and Karperien, H.B.J. (2012) Gremlin 1, frizzled-related protein, and Dkk-1 are key regulators of human articular cartilage homeostasis: Article recommendation on F1000Prime. UNSPECIFIED.

Moreira Teixeira, L.S. and Leijten, J.C.H. and Sobral, J. and Jin, R. and Apeldoorn van, A.A. and Feijen, J. and Blitterswijk van, C.A. and Dijkstra, P.J. and Karperien, H.B.J. (2012) High throughput generated micro-aggregates of chondrocytes stimulate cartilage formation in vitro and in vivo. European cells & materials, 23 . 387 - 399. ISSN 1473-2262

Leijten, J.C.H. and Moreira Teixeira, L.S. and Landman, E.B.M. and Blitterswijk van, C.A. and Karperien, H.B.J. (2012) Hypoxia Inhibits Hypertrophic Differentiation and Endochondral Ossification in Explanted Tibiae. PLoS ONE, 7 (11). 1 - 7. ISSN 1932-6203

Croisier, F. and Duwez, A.-S. and Jerome, C. and Leanard, A.F. and Werf van der, K.O. and Dijkstra, P.J. and Bennink, M.L. (2012) Mechanical testing of electrospun PCL fibers. Acta biomaterialia, 8 (1). 218 - 224. ISSN 1742-7061

Wu, L. (2012) Mesenchymal stem cells as trophic mediators in cartilage regeneration. thesis.

Schivo, S. and Scholma, J. and Wanders, B. and Urquidi Camacho, R.A. and Vet van der, P.E. and Karperien, H.B.J. and Langerak, R. and Pol van de, J.C. and Post, J.N. (2012) Modelling biological pathway dynamics with Timed Automata. In: 12th IEEE International Conference on Bioinformatics and Bioengineering, BIBE 2012, 11-13 November 2012, Larnaca, Cyprus.

Chinnagounder Periyasamy, P. and Leijten, J.C.H. and Dijkstra, P.J. and Karperien, H.B.J. and Post, J.N. (2012) Nanomaterials for the Local and Targeted Delivery of Osteoarthritis Drugs. Journal of Nanomaterials, 2012 . p. 673968. ISSN 1687-4110

Buckland, J. and Leijten, J.C.H. and Blitterswijk van, C.A. and Karperien, H.B.J. (2012) Osteoarthritis: Control of human cartilage hypertrophic differentiation. Research highlight van: Gremlin1, frizzled-related protein, and Dkk-1 are key regulators of human articular cartilage homeostasis. Nature Reviews Rheumatology, 8 . 368 - . ISSN 1759-4790

Basalus, M.Z. and Tandjung, K. and Sen, H. and Apeldoorn van, A.A. and Grijpma, D.W. and Birgelen von, C. (2012) Recent insights from scanning electron microscopic assessment of durable polymer-coated drug-eluting stents. Interventional cardiology, 4 . 661 - 674. ISSN 1755-5302

Kunstar, A. and Leijten, J.C.H. and Leuveren van, S. and Hilderink, J. and Otto, C. and Blitterswijk van, C.A. and Karperien, H.B.J. and Apeldoorn van, A.A. (2012) Recognizing different tissues in human fetal femur cartilage by label-free Raman microspectroscopy. Journal of biomedical optics, 17 (11). p. 116012. ISSN 1083-3668

Basalus, M.W. and Tandjung, K. and Westen van, T. and Sen, H. and Jagt van der, P.K.N. and Grijpma, D.W. and Apeldoorn van, A.A. and Birgelen von, C. (2012) Scanning electron microscopic assessment of coating irregularities and their precursors in unexpanded durable polymer-based drug-eluting stents. Catheterization and cardiovascular interventions, 79 (4). 644 - 653. ISSN 1522-1946

Moreira Teixeira, L.S. and Bijl, S. and Pully, V.V. and Otto, C. and Jin, R. and Feijen, J. and Blitterswijk van, C.A. and Dijkstra, P.J. and Karperien, H.B.J. (2012) Self-attaching and cell-attracting in-situ forming dextran-tyramine conjugates hydrogels for arthroscopic cartilage repair. Biomaterials, 33 (11). 3164 - 3174. ISSN 0142-9612

Moreira Teixeira, L.S. and Leijten, J.C.H. and Wennink, J.W.H. and Chatterjea, A. and Feijen, J. and Blitterswijk van, C.A. and Dijkstra, P.J. and Karperien, M. (2012) The effect of platelet lysate supplementation of a dextran-based hydrogel on cartilage formation. Biomaterials, 33 (14). 3651 - 3661. ISSN 0142-9612

Leijten, J.C.H. (2012) Vroege opsporing Artrose wordt eenvoudiger. In Beweging (Maandblad voor Reumapatiënten) .

Lourenco, B.N. and Marchioli, G. and Song, W and Reis, R.L. and Blitterswijk van, C.A. and Karperien, H.B.J. and Apeldoorn van, A.A. and Mano, J.F. (2012) Wettability influences cell behavior on superhydrophobic surfaces with different topographies. Biointerphases, 7 (1-4). 1 - 11. ISSN 1934-8630

2011

Both, Sanne K. and Apeldoorn van, Aart A. and Jukes, Jojanneke M. and Englund, Mikael C.O. and Hyllner, Johan and Blitterswijk van, Clemens A. and Boer de, Jan (2011) Differential bone-forming capacity of osteogenic cells from either embryonic stem cells or bone marrow-derived mesenchymal stem cells. Journal of Tissue Engineering and Regenerative Medicine, 5 (3). pp. 180-190. ISSN 1932-6254

Meijer, D. and Gelderblom, Hans and Karperien, H.B.J. and Cleton-Jansen, A.M. and Hogendoorn, C.W. and Bovee, J. (2011) Expression of aromatase and estrogen receptor alpha in chondrosarcoma, but no beneficial effect of inhibiting estrogen signaling both in vitro and in vivo. Clinical sarcoma research, 1 . p. 5. ISSN 2045-3329