Author Publications

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Number of items: 62.

2013

Daoudi, K. and Es, P. van and Manohar, S. and Steenbergen, W. (2013) Two-dimensional spatiotemporal monitoring of temperature in photothermal therapy using hybrid photoacoustic-ultrasound transmission tomography. Journal of biomedical optics, 18 (11). 116009-1 - 116009-5. ISSN 1083-3668

Grootendorst, D.J. and Fratila, R.M. and Visscher, M. and Haken, B. ten and Wezel, R.J.A. van and Rottenberg, S. and Steenbergen, W. and Manohar, S. and Ruers, T.J.M. (2013) Intra-operative ex vivo photoacoustic nodal staging in a rat model using a clinical superparamagnetic iron oxide nanoparticle dispersion. Journal of biophotonics, 6 (6-7). 493 - 504. ISSN 1864-063x

Grootendorst, D.J. and Fratila, R.M. and Visscher, M. and Haken, B. ten and Wezel, R.J.A. van and Steenbergen, W. and Manohar, S. and Ruers, T.J.M. (2013) Photoacoustic intra-operative nodal staging using clinically approved superparamagnetic iron oxide nanoparticles. In: Proceedings of SPIE Vol.8581 Photons Plus Ultrasound: Imaging and Sensing 2013, San Francisco, USA, 2013-02-02, San Francisco, USA (pp. 256 - 256).

Grootendorst, D.J. and Jose, J. and Fratila, R.M. and Visscher, M. and Velders, A.H. and Haken, B. ten and Leeuwen, A.G.J.M. van and Steenbergen, W. and Manohar, S. and Ruers, T.J.M. (2013) Evaluation of superparamagnetic iron oxide nanoparticles (Endorem) as a photoacoustic contrast agent for intra-operative nodal staging. Contrast media & molecular imaging, 8 (1). 83 - 91. ISSN 1555-4309

Grootendorst, D.J. and Steenbergen, W. and Manohar, S. and Ruers, T.J.M. (2013) Optical techniques for the intraoperative assessment of nodal status. Future oncology, 9 (11). 1741 - 1755. ISSN 1479-6694

Heijblom, M. and Meijer, L.M. and Leeuwen, A.G.J.M. van and Steenbergen, W. and Manohar, S. (2013) Monte Carlo simulations shed light on Bathsheba's suspect breast. Journal of biophotonics, accepted . ISSN 1864-063x

Heijblom, M. and Piras, D. and Engh, F.M. van den and Klaase, Joost M. and Brinkhuis, M. and Steenbergen, W. and Manohar, S. (2013) Photoacoustic imaging of breast tumor vascularization: a comparison with MRI and histopathology. In: European Conferences on Biomedical Optics. International Society for Optics and Photonics (pp. 88004 -).

Heijblom, M. and Piras, D. and Maartens, E. and Huisman, E.J.J. and Engh, F.M. van den and Klaase, Joost M. and Steenbergen, W. and Manohar, S. (2013) Appearance of breast cysts in planar geometry photoacoustic mammography using 1064-nm excitation. Journal of biomedical optics, 18 (12). 126009-1 - 126009-11. ISSN 1083-3668

Manohar, S. (2013) System for enabling generation of photoacoustic images. Patent.

Piras, D. and Grijsen, C. and Schutte, P. and Steenbergen, W. and Manohar, S. (2013) Photoacoustic needle: minimally invasive guidance to biopsy. Journal of biomedical optics, 18 (7). 070502-1 - 070502-3. ISSN 1083-3668

Ungureanu, C. and Koning, G. and Leeuwen, A.G.J.M. van and Manohar, S. (2013) The 'nanobig rod' class of gold nanorods: optimized dimensions for improved in vivo therapeutic and imaging efficacy. Nanotechnology, 24 (21). 1 - 9. ISSN 0957-4484

Xia, W. and Piras, D. and Hespen, J.C.G. van and Singh, M.K.A. and Leeuwen, A.G.J.M. van and Steenbergen, W. and Manohar, S. (2013) Design and evaluation of a laboratory prototype system for 3D photoacoustic full breast tomography. Biomedical optics express, 4 (11). 2555 - 2569. ISSN 2156-7085

Xia, W. and Piras, D. and Hespen, J.C.G. van and Singh, M.K.A. and Veldhoven, S. van and Prins, C. and Leeuwen, A.G.J.M. van and Steenbergen, W. and Manohar, S. (2013) Design considerations for ultrasound detectors in photoacoustic breast imaging. In: Photons Plus Ultrasound: Imaging and Sensing 2013, 02-02-2013, San Francisco, CA, USA (pp. 858113 -).

Xia, Wenfeng and Piras, Daniele and Hespen, Johan C.G. van and Steenbergen, Wiendelt and Manohar, Srirang (2013) A new acoustic lens material for large area detectors in photoacoustic breast tomography. Photoacoustics, 1 (2). 9 - 18. ISSN 2213-5979

Xia, Wenfeng and Piras, Daniele and Hespen, Johan C.G. van and Veldhoven, Spiridon van and Prins, Christian and Leeuwen, Ton G. van and Steenbergen, Wiendelt and Manohar, Srirang (2013) An optimized ultrasound detector for photoacoustic breast tomography. Medical physics, 40 (3). 032901. ISSN 0094-2405

2012

Es, P. van and Leeuwen, A.G.J.M. van and Steenbergen, W. and Manohar, S. (2012) Multimodal Photoacoustic and Ultrasound Imaging. In: Emerging Imaging Technologies in Medicine. Taylor and Francis, 233 - 252. ISBN 9781439880418

Grootendorst, D.J. and Jose, J. and Fratila, R.M. and Visscher, M. and Velders, A.H. and Haken, B. ten and Leeuwen, A.G.J.M. van and Steenbergen, W. and Manohar, S. and Ruers, T.J.M. (2012) Photoacoustic metastases detection using clinically approved SPIO dispersions. In: OSA Biomedical Optics Conference, April 29 to May 2, 2012, 2012-05-01, Miami, FL.

Grootendorst, D.J. and Jose, J. and Wouters, M.W. and Boven, H.H. van and Hage, J.A. van der and Haken, B. ten and Leeuwen, A.G.J.M. van and Steenbergen, W. and Manohar, S. and Ruers, T.J.M. (2012) First Experiences of Photoacoustic Imaging for Detection of Melanoma Metastases in Resected Human Lymph Nodes. Lasers in surgery and medicine, 44 (7). 541 - 549. ISSN 0196-8092

Hartsuiker, L. and Petersen, W. and Rayavarapu, R.G. and Lenferink, A.T.M. and Poot, A.A. and Terstappen, L.W.M.M. and Leeuwen, A.G.J.M. van and Manohar, S. and Otto, C. (2012) Raman and Fluorescence Spectral Imaging of Live Breast Cancer Cells Incubated with PEGylated Gold Nanorods. Applied spectroscopy, 66 (1). 66 - 74. ISSN 0003-7028

Heijblom, M. and Piras, D. and Xia, W. and Hespen, J.C.G. van and Klaase, J.M. and Engh, F.M. van den and Leeuwen, A.G.J.M. van and Steenbergen, W. and Manohar, S. (2012) Imaging breast lesions using the Twente Photoacoustic Mammoscope: ongoing clinical experience. In: SPIE Photons plus Ultrasound: imaging and sensing 2012, Photonics West, 2012-01-20, San Francisco, USA.

Heijblom, M. and Piras, D. and Xia, W. and Hespen, J.C.G. van and Klaase, J.M. and Engh, F.M. van den and Leeuwen, A.G.J.M. van and Steenbergen, W. and Manohar, S. (2012) Visualizing breast cancer using the Twente photoacoustic mammoscope: What do we learn from twelve new patient measurements? Optics express, 20 (11). 11582 - 11597. ISSN 1094-4087

Jose, J. and Willemink, G.H. and Steenbergen, W. and Leeuwen, A.G.J.M. van and Manohar, S. (2012) Speed-of-sound compensated photoacoustic tomography for accurate imaging. Medical physics, 39 (12). 7262 - 7272. ISSN 0094-2405

Piras, D. and Heijblom, M. and Xia, W. and Leeuwen, A.G.J.M. van and Steenbergen, W. and Manohar, S. (2012) Adapted directivity approach for photoacoustic imaging reconstruction. In: Photons Plus Ultrasound: Imaging and Sensing 2012, January 21, 2012.

Xia, W. and Piras, D. and Heijblom, M. and Hespen, J.C.G. van and Veldhoven, S. van and Prins, C. and Leeuwen, A.G.J.M. van and Steenbergen, W. and Manohar, S. (2012) A Custom-Made Linear Array Transducer for Photoacoustic Breast Imaging. In: Photons Plus Ultrasound: Imaging and Sensing 2012, 2012-01-23, San Francisco, USA.

Xia, W. and Piras, D. and Hespen, J.C.G. van and Veldhoven, S. van and Prins, C. and Leeuwen, A.G.J.M. van and Steenbergen, W. and Manohar, S. (2012) A Novel Acoustic Lens for Photoacoustic Breast Imaging. In: OSA Biomedical Optics Conference, April 29 to May 2, 2012, 2012-05-01, Miami, USA.

Xia, W. and Piras, D. and Veldhoven, S. van and Prins, C. and Leeuwen, A.G.J.M. van and Steenbergen, W. and Manohar, S. (2012) FEM model based optimization of transducer geometry for photoacoustic imaging. In: OSA Conference on Biomedical Optics, BIOMED 2012, Miami, Florida, April 28, 2012, April 28, 2012, Miami, FL, USA.

2011

Grootendorst, D. and Jose, J. and Jagt, P. van der and Weg, W. van der and Nagel, K. and Wouters, M. and Boven, H. van and Leeuwen, T.G. van and Steenbergen, W. and Ruers, T. and Manohar, S. (2011) Initial experiences in the photoacoustic detection of melanoma metastases in resected lymph nodes. In: Photons Plus Ultrasound: Imaging and Sensing 2011, April 11, 2011, San Francisco, CA, USA.

Hartsuiker, L. and Petersen, W. and Jose, J. and Es, P. van and Lenferink, A. and Poot, A.A. and Terstappen, L.W.M.M. and Manohar, S. and Otto, C. and Leeuwen, T.G. van (2011) Gold nanoparticles for tumour detection and treatment. In: Clinical and Biomedical Spectroscopy and Imaging II. Proceedings of SPIE, 8087 . Society of Photo-Optical Instrumentation Engineers, p. 808710.

Heijblom, M. and Klaase, J.M. and Engh, F.M. van den and Leeuwen, T.G. van and Steenbergen, W. and Manohar, S. (2011) Imaging Tumor Vascularization for Detection and Diagnosis of Breast Cancer. Technology in cancer research & treatment, 10 (6). pp. 607-623. ISSN 1533--0338

Heijblom, Michelle and Piras, Daniele and Tije, Ellen ten and Xia, Wenfeng and Hespen, Johan van and Steenbergen, Wiendelt and Manohar, Srirang and Klaase, Joost and Engh, Frank van den and Leeuwen, Ton van (2011) Breast imaging using the Twente photoacoustic mammoscope (PAM): new clinical measurements. In: Clinical and Biomedical Spectroscopy and Imaging II. Proceedings of SPIE, 8087 . Society of Photo-Optical Instrumentation Engineers, 80870N.

Hilgerink, Marjolein P. and Hummel, J.M. and Manohar, Srirang and Vaartjes, Simon R. and IJzerman, Maarten J. (2011) Assessment of the added value of the Twente Photoacoustic Mammoscope in breast cancer diagnosis. Medical Devices: Evidence and Research, 2011 (4). pp. 107-115. ISSN 1179-1470

Jose, Jithin and Grootendorst, Diederik J. and Vijn, Thomas W. and Wouters, Michel and Boven, Hester van and Leeuwen, Ton G. van and Steenbergen, Wiendelt and Ruers, Theo J.M. and Manohar, Srirang (2011) Initial results of imaging melanoma metastasis in resected human lymph nodes using photoacoustic computed tomography. Journal of Biomedical Optics, 16 (9). 096021 . ISSN 1083-3668

Jose, Jithin and Willemink, Rene G.H. and Resink, Steffen and Piras, Daniele and Hespen, J.C.G. van and Slump, Cornelis H. and Steenbergen, Wiendelt and Leeuwen, Ton G. van and Manohar, Srirang (2011) Passive element enriched photoacoustic computed tomography (PER PACT) for simultaneous imaging of acoustic propagation properties and light absorption. Optics Express, 19 (3). pp. 2093-2104. ISSN 1094-4087

Lankveld, Danielle P.K. and Rayavarapu, Raja G. and Krystek, Petra and Oomen, Agnes G. and Verharen, Hennie W. and Leeuwen, Ton G. van and Jong, Wim H. de and Manohar, Srirang (2011) Blood clearance and tissue distribution of PEGylated and non-PEGylated gold nanorods after intravenous administration in rats. Nanomedicine, 6 (2). pp. 339-349. ISSN 1743-5889

Manohar, Srirang and Ungureanu, Constantin and Leeuwen, Ton G. van (2011) Gold nanorods as molecular contrast agents in photoacoustic imaging: the promises and the caveats. Contrast media and molecular imaging, 62 (5). pp. 389-400. ISSN 1555-4309

Piras, D. and Xia, W. and Heijblom, M. and Tije, E.M. ten and Hespen, J. van and Steenbergen, W. and Leeuwen, T.G. van and Manohar, S. and Engh, F. van den and Klaase, J.M. (2011) Breast imaging with the Twente Photoacoustic Mammoscope. In: International Workshop BioPhotonics, 2011, 8-10 June 2011, Parma, Italy.

Resink, S.G. and Jose, J. and Willemink, R.G.H. and Slump, C.H. and Steenbergen, W. and Leeuwen, A.G.J.M. van and Manohar, S. (2011) Multiple passive element enriched photoacoustic computed tomography. Optics Letters, 36 (15). pp. 2809-2811. ISSN 0146-9592

Slump, C.H. and Willemink, R.G.H. and Manohar, S. and Hoenders, B.J. (2011) On the role of passive elements in photoacoustic reconstruction. In: Photons Plus Ultrasound: Imaging and Sensing 2011, February 17, 2011, San Francisco, CA, USA.

Ungureanu, Constantin and Kroes, Rene and Petersen, Wilma and Groothuis, Tom A.M. and Ungureanu, Felicia and Janssen, Hans and Leeuwen, Fijs W.B. van and Kooyman, Rob P.H. and Manohar, Srirang and Leeuwen, Ton G. van (2011) Light Interactions with Gold Nanorods and Cells: Implications for Photothermal Nanotherapeutics. Nano Letters, 11 (5). pp. 1887-1894. ISSN 1530-6984

Xia, Wenfeng and Piras, Daniele and Heijblom, Michelle and Hespen, Johan C.G. van and Steenbergen, Wiendelt and Manohar, Srirang and Veldhoven, Spiridon van and Prins, Christian and Leeuwen, Ton G. van (2011) Enlarged acceptance angle of a finite size detector in photoacoustic imaging using acoustic lenses. In: Novel Biophotonic Techniques and Applications. Proceedings of SPIE, 8090 . Society of Photo-Optical Instrumentation Engineers, 80900L.

Xia, Wenfeng and Piras, Daniele and Heijblom, Michelle and Steenbergen, Wiendelt and Leeuwen, Ton van and Manohar, Srirang (2011) Poly(vinyl alcohol) gels as photoacoustic breast phantoms revisited. Journal of Biomedical Optics, 16 (7). 075002. ISSN 1083-3668

2010

Piras, Daniele and Xia, Wenfeng and Steenbergen, Wiendelt and Leeuwen, Ton G. van and Manohar, Srirang (2010) Photoacoustic Imaging of the Breast Using the Twente Photoacoustic Mammoscope: Present Status and Future Perspectives. IEEE Journal on Selected topics in Quantum Electronics, 16 (4). pp. 730-739. ISSN 1077-260X

Rayavarapu, Raja G. and Petersen, Wilma and Hartsuiker, Liesbeth and Chin, Patrick and Janssen, Hans and Leeuwen, Fijs W.B. van and Otto, Cees and Manohar, Srirang and Leeuwen, Ton G. van (2010) In vitro toxicity studies of polymer-coated gold nanorods. Nanotechnology, 21 (14). p. 145101. ISSN 0957-4484

Rayavarapu, Raja Gopal and Ungureanu, Constantin and Krystec, Petra and Leeuwen, Ton G. van and Manohar, Srirang (2010) Iodide Impurities in Hexadecyltrimethylammonium Bromide (CTAB) Products: Lot−Lot Variations and Influence on Gold Nanorod Synthesis. Langmuir, 26 (7). 5050 - 5055. ISSN 0743-7463

Ungureanu, Constantin and Amelink, Arjen and Rayavarapu, Raja G. and Sterenborg, Henricus J.C.M. and Manohar, Srirang and Leeuwen, Ton G. van (2010) Differential Pathlength Spectroscopy for the Quantitation of Optical Properties of Gold Nanoparticles. ACS Nano, 4 (7). pp. 4081-4089. ISSN 1936-0851

2009

Jose, J. and Willemink, R. and Resink, S.G. and Maalderink, T. and Hespen, J.C.G. van and Leeuwen, T.G. van and Manohar, S. (2009) Ultrasound-transmission parameter imaging in a photoacoustic imager. In: Novel Optical Instrumentation for Biomedical Applications IV. Proceedings of SPIE, 7371 . SPIE/OSA, 73710S. ISBN 9780819476470

Jose, Jithin and Manohar, Srirang and Kolkman, Roy G.M. and Steenbergen, W. and Leeuwen, Ton G. van (2009) Imaging of tumor vasculature using Twente photoacoustic systems. Journal of Biophotonics, 2 (12). pp. 701-717. ISSN 1864-063X

Manohar, Srirang and Rayavarapu, Rajagopal and Petersen, Wilma and Leeuwen, Ton G. van (2009) Cell viability studies of PEG-thiol treated gold nanorods as optoacoustic contrast agents. In: Photons Plus Ultrasound: Imaging and Sensing 2009. Proceedings of SPIE, 7177 . SPIE, 71772D. ISBN 9780819474230

Ungureanu, C. and Manohar, S. and Leeuwen, T.G.C. van and Amelink, A. and Sterenborg, Henricus J.C.M. (2009) Discriminating between absorption and scattering coefficients in optical characterisation measurements on gold nanoparticle based photoacoustic contrast agents. In: Photons Plus Ultrasound: Imaging and Sensing 2009. Proceedings of SPIE, 7177 . SPIE, p. 717718.

Ungureanu, Constantin and Rayavarapu, Raja Gopal and Manohar, Srirang and Leeuwen, Ton G. van (2009) Discrete dipole approximation simulations of gold nanorod optical properties: Choice of input parameters and comparison with experiment. Journal of Applied Physics, 105 (10). p. 102032. ISSN 0021-8979

Willemink, Rene G.H. and Manohar, Srirang and Jose, Jithin and Slump, Kees and Heijden, Ferdi van der and Leeuwen, Ton G. van (2009) Simultaneous imaging of ultrasound attenuation, speed of sound and optical absorption in a photoacoustic setup. In: Medical Imaging 2009: Ultrasonic Imaging and Signal Processing. Proceedings of SPIE, 7265 . SPIE, 72650J. ISBN 9780819475169

2008

Manohar, Srirang and Willemink, Rene G. (2008) Hybrid photoacoustic - ultrasound transmission parameter imaging in a miniature photoacoustic imager (A). Journal of the Acoustical Society of America, 123 (5). p. 3371. ISSN 0001-4966

Willemink, G.H. and Manohar, S. and Purwar, Y. and Slump, C.H. and van der Heijden, F. and van Leeuwen, T.G. (2008) Imaging of acoustic attenuation and speed of sound maps using photoacoustic measurements. In: Medical Imaging 2008: Ultrasonic Imaging and Signal Processing, San Diego, CA, USA (pp. 692013-1-692013-12).

2007

Manohar, Srirang and Willemink, Rene G.H. and Heijden, Ferdi van der and Slump, Cornelis H. and Leeuwen, Ton G. van (2007) Concomitant speed-of-sound tomography in photoacoustic imaging. Applied physics letters, 91 (13). p. 131911. ISSN 0003-6951

Manohar, Srirang and Vaartjes, Susanne E. and Hespen, Johan C.G. van and Klaase, Joost M. and Engh, Frank M. van den and Steenbergen, Wiendelt and Leeuwen, Ton G. van (2007) Initial results of in vivo non-invasive cancer imaging in the human breast using near-infrared photoacoustics. Optics Express, 15 (19). pp. 12277-12285. ISSN 1094-4087

Manohar, Srirang and Willemink, Rene G.H. and Leeuwen, Ton G. van (2007) Speed-of-sound imaging in a photoacoustic imager. In: Eighth Conference on Biomedical Thermoacoustics, Optoacoustics, and Acousto-optics; Photons Plus Ultrasound: Imaging and Sensing, 13-15 February 2007, San Jose, CA, USA (pp. p. 64370).

Rayavarapu, Raja Gopal and Petersen, Wilma and Ungureanu, Constantin and Post, Janine N. and Leeuwen, Ton G. van and Manohar, Srirang (2007) Synthesis and Bioconjugation of Gold Nanoparticles as Potential Molecular Probes for Light-Based Imaging Techniques. International Journal of Biomedical Imaging . p. 29817. ISSN 1687-4196

Ungureanu, C. and Gopal, R. Raja and Leeuwen, T.G. van and Manohar, S. (2007) Optical properties of gold nanorods: towards contrast agents for photoacoustic imaging [poster]. In: 3rd International Graduate Summer School Biophotonics ’07, 9-16 June, 2007, Ven, Sweden.

Willemink, G.H. and Manohar, S. and Slump, C.H. and van der Heijden, F. and van Leeuwen, T.G. (2007) Acoustic property measurements in a photoacoustic imager. In: Novel optical instrumentation for biomedical applications III, 17-19 Jul 2007, Munich, Germany (pp. pp. 1-9).

2005

Manohar, Srirang and Kharine, Alexei and Hespen, Johan C.G. van and Steenbergen, Wiendelt and Leeuwen, Ton G. van (2005) The Twente Photoacoustic Mammoscope: system overview and performance. Physics in Medicine and Biology, 50 (11). pp. 2543-2557. ISSN 0031-9155

Manohar, Srirang and Murugavel, S. and Asokan, S. (2005) Thermal diffusivities and molar volumes of ternary Al20 AsxTe80−x alloy glasses: evidence of self-organization. Solid State Communications, 135 (5). pp. 323-326. ISSN 0038-1098

2003

Kharine, Alexei and Manohar, Srirang and Seeton, Rosalyn and Kolkman, Roy G.M. and Bolt, Rene A. and Steenbergen, Wiendelt and Mul, Frits F.M. de (2003) Poly(vinyl alcohol) gels for use as tissue phantoms in photoacousttc mammography. Physics in Medicine and Biology, 48 (3). pp. 357-370. ISSN 0031-9155

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