Author Publications

2013

Higuera Sierra, G.A. and Hendriks, J.A. and Dalum van, J. and Wu, L. and Schotel, R. and Moreira Teixeira, L.S. and Doel van den, M. and Leijten, J.C.H. and Riesle, J. and Karperien, H.B.J. and Blitterswijk van, C.A. and Moroni, L. (2013) In vivo screening of extracellular matrix components produced under multiple experimental conditions implanted in one animal. Integrative Biology . ISSN 1757-9694

Karperien, H.B.J. (2013) Injecteerbare pleister op komst. RondReuma, 2013 (maart). 4 - 6. ISSN 1566-6018

Ling, W. and Leijten, J.C.H. and Post, J.N. and Karperien, H.B.J. (2013) Fibroblast growth factor-1 is a mesenchymal stromal cell secreted factor stimulating proliferation of Osteoarthritic chondrocytes. In: World Congress on Osteoarthritis, OARSI 2013, Philadelphia, PA, USA, April 18-21, 2013, April 18-21, 2013, Philadelphia.

Ma, B. and Landman, E.B.M. and Miclea, R.L. and Wit, J.M. and Robanus-Maandag, E.C. and Post, J.N. and Karperien, H.B.J. (2013) WNT Signaling and Cartilage: Of Mice and Men. Calcified tissue international, 92 (5). 399 - 411. ISSN 0171-967X

Ma, B. and Leijten, J.C.H. and Wu, L. and Kip, M. and Blitterswijk van, C.A. and Post, J.N. and Karperien, H.B.J. (2013) Gene expression profiling of dedifferentiated human articular chondrocytes in monolayer culture. Osteoarthritis and cartilage, 21 (4). 599 - 603. ISSN 1063-4584

Ma, B. and Zhong, L. and Blitterswijk van, C.A. and Post, J.N. and Karperien, H.B.J. (2013) TCF4 is a pro-catabolic and apoptotic factor in human articular chondrocytes by potentiating NF-κB signaling. Journal of biological chemistry . ISSN 1083-351X

Silva, J.M. and Georgi, N. and Costa, R. and Sher, P. and Reis, R.L. and Blitterswijk van, C.A. and Karperien, H.B.J. and Mano, J.F. (2013) Nanostructured 3D Constructs Based on Chitosan and Chondroitin Sulphate Multilayers for Cartilage Tissue Engineering. PLoS ONE, 8 (2). e55451. ISSN 1932-6203

Spitters, T.W.G.M. and Leijten, J.C.H. and Deus, F.D. and Costa, I.B.F. and Apeldoorn van, A.A. and Blitterswijk van, C.A. and Karperien, H.B.J. (2013) A dual flow bioreactor with controlled mechanical stimulation for cartilage tissue engineering. Tissue Engineering. Part C Methods . ISSN 1937-3384

2012

Buckland, J. and Leijten, J.C.H. and Blitterswijk van, C.A. and Karperien, H.B.J. (2012) Osteoarthritis: Control of human cartilage hypertrophic differentiation. Research highlight van: Gremlin1, frizzled-related protein, and Dkk-1 are key regulators of human articular cartilage homeostasis. Nature Reviews Rheumatology, 8 . 368 - . ISSN 1759-4790

Chinnagounder Periyasamy, P. and Leijten, J.C.H. and Dijkstra, P.J. and Karperien, H.B.J. and Post, J.N. (2012) Nanomaterials for the Local and Targeted Delivery of Osteoarthritis Drugs. Journal of Nanomaterials, 2012 . p. 673968. ISSN 1687-4110

Duyvenvoorde, H.A. and Lui, J. and Kant, S.G. and Oostdijk, W. and Gijsbers, A.C.J. and Karperien, H.B.J. and Walenkamp, M.J.E. and Noordam, C. and Voorhoeve, P.G. and Mericq, V. and Gool van, S.A. and Breuning, M.H. and Losekoot, M. and Baron, J. and Ruivenkamp, C.A. and Wit, J.M. (2012) Copy number variations in patients with idiopathic short stature [Poster]. In: European Society for Pediatric Endocrinology.

Duyvenvoorde, H.A. and Ruivenkamp, C.A. and Mul, D. and Oostdijk, W. and Karperien, H.B.J. and Losekoot, M. and Pereira, A.M. and Kant, S.G. and Wit, J.M. (2012) A quest for copy number variations causing extreme tall stature. In: European Society for Pediatric Endocrinology.

Gool van, S.A. and Emons, J.A.M. and Leijten, J.C.H. and Decker, E. and Sticht, C. and Houwelingen van, J.C. and Goeman, J.J. and Kleijburg, C. and Scherjon, S. and Gretz, N. and Wit, J.M. and Rappold, G. and Post, J.N. and Karperien, H.B.J. (2012) Fetal Mesenchymal Stromal Cells Differentiating towards Chondrocytes Acquire a Gene Expression Profile Resembling Human Growth Plate Cartilage. PLoS ONE, 7 (11). 1 - 11. ISSN 1932-6203

Higuera, G. and Schop, D. and Spitters, T.W.G.M. and Dijkhuizen-Radersma van, R. and Bracke, M. and Bruijn de, J.D. and Martens, D.E. and Karperien, H.B.J. and Boxtel van, A.J.B. and Blitterswijk van, C.A. (2012) Patterns of amino Acid metabolism by proliferating human mesenchymal stem cells. Tissue Engineering. Part A, 18 (5). 654 - 664. ISSN 1937-3341

Kunstar, A. and Leijten, J.C.H. and Leuveren van, S. and Hilderink, J. and Otto, C. and Blitterswijk van, C.A. and Karperien, H.B.J. and Apeldoorn van, A.A. (2012) Recognizing different tissues in human fetal femur cartilage by label-free Raman microspectroscopy. Journal of biomedical optics, 17 (11). p. 116012. ISSN 1083-3668

Leijten, J.C.H. and Emons, J. and Sticht, C. and Gool van, S. and Decker, E. and Uitterlinden, A. and Rappold, G. and Hofman, A. and Rivadeneira, F. and Scherjon, S. and Wit, J.M. and Meurs van, J. and Blitterswijk van, C.A. and Karperien, H.B.J. (2012) Gremlin 1, Frizzled-related protein, and Dkk-1 are key regulators of human articular cartilage homeostasis. Arthritis & rheumatism, 64 (10). 3302 - 3312. ISSN 1529-0131

Leijten, J.C.H. and Emons, J. and Sticht, C. and Gool van, S. and Decker, E. and Uitterlinden, A. and Rappold, G. and Hofman, A. and Rivadeneira, F. and Scherjon, S. and Wit, J.M. and Meurs van, J. and Blitterswijk van, C.A. and Karperien, H.B.J. (2012) Gremlin 1, frizzled-related protein, and Dkk-1 are key regulators of human articular cartilage homeostasis: Article recommendation on F1000Prime. UNSPECIFIED.

Leijten, J.C.H. and Moreira Teixeira, L.S. and Landman, E.B.M. and Blitterswijk van, C.A. and Karperien, H.B.J. (2012) Hypoxia Inhibits Hypertrophic Differentiation and Endochondral Ossification in Explanted Tibiae. PLoS ONE, 7 (11). 1 - 7. ISSN 1932-6203

Leijten, J.C.H. and Georgi, N. and Wu, L. and Blitterswijk van, C.A. and Karperien, H.B.J. (2012) Cell sources for articular cartilage repair strategies: shifting from mono-cultures to co-cultures. Tissue Engineering. Part B, 19 (1). pp. 31-40. ISSN 1937-3368

Lourenco, B.N. and Marchioli, G. and Song, W and Reis, R.L. and Blitterswijk van, C.A. and Karperien, H.B.J. and Apeldoorn van, A.A. and Mano, J.F. (2012) Wettability influences cell behavior on superhydrophobic surfaces with different topographies. Biointerphases, 7 (1-4). 1 - 11. ISSN 1934-8630

Ma, B. and Blitterswijk van, C.A. and Karperien, H.B.J. (2012) A Wnt/ß-catenin negative feedback loop inhibits IL-1-induced MMP expression in human articular chondrocytes. Arthritis and rheumatism, 64 . 2589 - 2600. ISSN 0004-3591

Ma, B. and Blitterswijk van, C.A. and Karperien, H.B.J. (2012) A Wnt/β-catenin negative feedback loop inhibits interleukin-1–induced matrix metalloproteinase expression in human articular chondrocytes. Arthritis & rheumatism, 64 (8). 2589 - 2600. ISSN 1529-0131

Moreira Teixeira, L.S. and Bijl, S. and Pully, V.V. and Otto, C. and Jin, R. and Feijen, J. and Blitterswijk van, C.A. and Dijkstra, P.J. and Karperien, H.B.J. (2012) Self-attaching and cell-attracting in-situ forming dextran-tyramine conjugates hydrogels for arthroscopic cartilage repair. Biomaterials, 33 (11). 3164 - 3174. ISSN 0142-9612

Moreira Teixeira, L.S. and Feijen, J. and Blitterswijk van, C.A. and Dijkstra, P.J. and Karperien, H.B.J. (2012) Enzyme-catalyzed crosslinkable hydrogels: Emerging strategies for tissue engineering. Biomaterials, 33 (5). 1281 - 1290. ISSN 0142-9612

Moreira Teixeira, L.S. and Leijten, J.C.H. and Sobral, J. and Jin, R. and Apeldoorn van, A.A. and Feijen, J. and Blitterswijk van, C.A. and Dijkstra, P.J. and Karperien, H.B.J. (2012) High throughput generated micro-aggregates of chondrocytes stimulate cartilage formation in vitro and in vivo. European cells & materials, 23 . 387 - 399. ISSN 1473-2262

Moreira Teixeira, L.S. and Leijten, J.C.H. and Wennink, J.W.H. and Chatterjea, A. and Feijen, J. and Blitterswijk van, C.A. and Dijkstra, P.J. and Karperien, M. (2012) The effect of platelet lysate supplementation of a dextran-based hydrogel on cartilage formation. Biomaterials, 33 (14). 3651 - 3661. ISSN 0142-9612

Schivo, S. and Scholma, J. and Wanders, B. and Urquidi Camacho, R.A. and Vet van der, P.E. and Karperien, H.B.J. and Langerak, R. and Pol van de, J.C. and Post, J.N. (2012) Modelling biological pathway dynamics with Timed Automata. In: 12th IEEE International Conference on Bioinformatics and Bioengineering, BIBE 2012, 11-13 November 2012, Larnaca, Cyprus.

Wu, L. and Prins, H.J. and Helder, M. and Blitterswijk van, C.A. and Karperien, H.B.J. (2012) Trophic Effects of Mesenchymal Stem Cells in Chondrocyte Co-Cultures are Independent of Culture Conditions and Cell Sources. Tissue Engineering. Part A, 18 (15-16). 1542 - 1551. ISSN 1937-3341

2011

Correia, Clara R. and Moreira Teixeira, Liliana S. and Moroni, Lorenzo and Reis, Rui L. and Blitterswijk van, Clemens A. and Karperien, Marcel and Mano, João F. (2011) Chitosan Scaffolds Containing Hyaluronic Acid for Cartilage Tissue Engineering. Tissue Engineering. Part C: methods, 17 (7). pp. 717-730. ISSN 1937-3384

Emons, Joyce and Dutilh, Bas E. and Decker, Eva and Pirzer, Heide and Sticht, Carsten and Gretz, Norbert and Rappold, Gudrun and Cameron, Ewan R. and Neil, James C. and Stein, Gary S. and Wijnen van, Andre J. and Wit, Jan Maarten and Post, Janine N. and Karperien, Marcel (2011) Genome-wide screening in human growth plates during puberty in one patient suggests a role for RUNX2 in epiphyseal maturation. Journal of endocrinology, 209 (2). pp. 245-254. ISSN 0022-0795

Jin, Rong and Moreira Teixeira, Liliana S. and Dijkstra, Pieter J. and Blitterswijk van, Clemens A. and Karperien, Marcel and Feijen, Jan (2011) Chondrogenesis in injectable enzymatically crosslinked heparin/dextran hydrogels. Journal of Controlled Release, 152 (1). pp. 186-195. ISSN 0168-3659

Kunstar, Aliz and Otto, Cees and Karperien, Marcel and Blitterswijk van, Clemens and Apeldoorn van, Aart (2011) Raman Microspectroscopy: A Noninvasive Analysis Tool for Monitoring of Collagen-Containing Extracellular Matrix Formation in a Medium-Throughput Culture System. Tissue Engineering. Part C: methods, 17 (7). pp. 737-744. ISSN 1937-3384

Meijer, D. and Gelderblom, Hans and Karperien, H.B.J. and Cleton-Jansen, A.M. and Hogendoorn, C.W. and Bovee, J. (2011) Expression of aromatase and estrogen receptor alpha in chondrosarcoma, but no beneficial effect of inhibiting estrogen signaling both in vitro and in vivo. Clinical sarcoma research, 1 . p. 5. ISSN 2045-3329

Neves, Sara C. and Moreira Teixeira, Liliana S. and Moroni, Lorenzo and Reis, Rui L. and Blitterswijk van, Clemens A. and Alves, Natália M. and Karperien, Marcel and Mano, João F. (2011) Chitosan/Poly(ɛ-caprolactone) blend scaffolds for cartilage repair. Biomaterials, 32 (4). pp. 1068-1079. ISSN 0142-9612

Wu, Ling and Leijten, Jeroen C.H. and Georgi, Nicole and Post, Janine N. and Blitterswijk van, Clemens A. and Karperien, Marcel (2011) Trophic Effects of Mesenchymal Stem Cells Increase Chondrocyte Proliferation and Matrix Formation. Tissue Engineering. Part A, 17 (9-10). pp. 1425-1436. ISSN 1937-3341

2010

Cai, Yongping and Mohseny, Alexander B. and Karperien, Marcel and Hogendoorn, Pancras C.W. and Zhou, Gengyin and Cleton-Jansen, Anne-Marie (2010) Inactive Wnt/β-catenin pathway in conventional high-grade osteosarcoma. Journal of Pathology, 220 (1). pp. 24-33. ISSN 0022-3417

Chung, P. and Beyens, G. and Boonen, S. and Papapoulos, S. and Geusens, P. and Karperien, H.B.J. and [et al.], (2010) The majority of the genetic risk for Paget’s disease of bone is explained by genetic variants close to the CSF1, OPTN, TM7SF4, and TNFRSF11A genes. Human genetics, 128 (6). pp. 615-626. ISSN 1018-4813

Hendriks, Jeanine A.A. and Miclea, Razvan L. and Schotel, Roka and Bruijn de, Ewart and Moroni, Lorenzo and Karperien, Marcel and Riesle, Jens and Blitterswijk van, Clemens A. (2010) Primary chondrocytes enhance cartilage tissue formation upon co-culture with a range of cell types. Soft Matter, 6 (20). pp. 5080-5088. ISSN 1744-683X

Jin, R. and Moreira Teixeira, L.S. and Dijkstra, P.J. and Karperien, H.B.J. and Blitterswijk van, C.A. and Feijen, J. (2010) Enzymatically-crosslinked injectable hydrogels based on biomimetic dextran–hyaluronic acid conjugates for cartilage tissue engineering. Biomaterials, 31 (11). pp. 3103-3113. ISSN 0142-9612

Jin, R. and Moreira Teixeira, L.S. and Krouwels, A. and Dijkstra, P.J. and Blitterswijk van, C.A. and Karperien, M. and Feijen, J. (2010) Synthesis and characterization of hyaluronic acid–poly(ethylene glycol) hydrogels via Michael addition: An injectable biomaterial for cartilage repair. Acta Biomaterialia, 6 (6). pp. 1968-1977. ISSN 1742-7061

2009

Jin, R. and Moreira Teixeira, L.S. and Dijkstra, P.J. and Karperien, M. and Blitterswijk van, C.A. and Zhong, Z.Y. and Feijen, J. (2009) Injectable chitosan-based hydrogels for cartilage tissue engineering. Biomaterials, 30 (13). pp. 2544-2551. ISSN 0142-9612

Miclea, R.L. and Karperien, H.B.J. and Bosch, C.A.J. and Horst van der, G. and Valk van der, M.A. and Kobayashi, T. and Kronenberg, H.M. and [et al.], (2009) Adenomatous polyposis coli-mediated control of β-catenin is essential for both chondrogenic and osteogenic differentiation of skeletal precursors. BMC developmental biology, 9 . p. 26. ISSN 1471-213X

Postnov, A. and Schutter de, T. and Sijbers, J. and Karperien, H.B.J. and Clerck de, N. (2009) Glucocorticoid-Induced Osteoporosis in Growing Mice Is Not Prevented by Simultaneous Intermittent PTH Treatment. Calcified tissue international, 85 (6). pp. 530-537. ISSN 0171-967x

Rivron, Nicolas C. and Rouwkema, Jeroen and Truckenmüller, Roman and Karperien, Marcel and Boer de, Jan and Blitterswijk van, Clemens A. (2009) Tissue assembly and organization: Developmental mechanisms in microfabricated tissues. Biomaterials, 30 (28). pp. 4851-4858. ISSN 0142-9612

2008

Chung, P.Y.J. and Beyens, G. and Guanabens, N. and Boonen, S. and Papapoulos, S. and Karperien, H.B.J. and Eekhoff, M. and Wesenbeek van, L. and [et al.], (2008) Founder Effect in Different European Countries for the Recurrent P392L SQSTM1 Mutation in Paget’s Disease of Bone. Calcified tissue international, 83 (1). pp. 34-42. ISSN 0171-967x

Jin, R. and Moreira Teixeira, L.S. and Dijkstra, P.J. and Karperien, M. and Zhong, Z. (2008) Fast in-situ formation of dextran-tyramine hydrogels for in vitro chondrocyte culturing. Journal of Controlled Release, 132 (3). e24-e26. ISSN 0168-3659

Karpan, Volodymyr Mykolajovych (2008) Towards perfect spin-filtering : a first-principles study. thesis.

Moreira Teixeira, L. and Jin, R. and Dijkstra, P.J. and Feijen, J. and Blitterswijk van, C. and Karperien, M. (2008) Chitosan-Based Hydrogels as Extracellular Matrix for Cartilage Tissue Engineering: In vitro Biological Evaluation. Tissue Engineering. Part A, 14 (5). p. 711. ISSN 1937-3341