Author Publications

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Number of items: 271.

2014

Barbieri, D. and Bruijn, J.D. de and Blitterswijk, C.A. van and Yuan, H. (2014) On the Horizon: Instructive nanomaterials hold the potential to mimic tissue complexity. IEEE pulse, 5 (2). 44 - 49. ISSN 2154-2287

Bettahalli, N.M.S. and Groen, N. and Steg, H. and Unadkat, H.V. and Boer, J. de and Blitterswijk, C.A. van and Wessling, M. and Stamatialis, D. (2014) Development of multilayer constructs for tissue engineering. Journal of tissue engineering and regenerative medicine, 8 (2). 106 - 119. ISSN 1932-6254

Cabanas-Danés, J. and Rodrigues, E.D. and Landman, Ellie B.M. and Weerd, J. van and Blitterswijk, C.A. van and Verrips, T. and Huskens, J. and Karperien, H.B.J. and Jonkheijm, Pascal (2014) A Supramolecular Host-Guest Carrier System for Growth Factors Employing VHH Fragments. Journal of the American Chemical Society, 136 (36). 12675 - 12681. ISSN 0002-7863

Chatterjea, A. and Stok, J. van der and Danoux, C.B.S.S. and Yuan, H. and Habibovic, P. and Blitterswijk, C.A. van and Weinans, H. and Boer, J. de (2014) Inflammatory response and bone healing capacity of two porous calcium phosphate ceramics in a critical size cortical bone defects. Journal of biomedical materials research part A, 102 (5). 1399 - 1407. ISSN 1549-3295

Chatterjea, Anindita and LaPointe, Vanessa L.S. and Alblas, Jacqueline and Chatterjea, Supriyo and Blitterswijk, Clemens A. van and Boer, Jan de (2014) Suppression of the immune system as a critical step for bone formation from allogeneic osteoprogenitors implanted in rats. Journal of cellular and molecular medicine, 18 (1). 134 - 142. ISSN 1582-1838

Danoux, Charlene B. and Barbieri, Davide and Yuan, Huipin and Bruijn, Joost D. de and Blitterswijk, Clemens A. van and Habibovic, Pamela (2014) In vitro and in vivo bioactivity assessment of a polylactic acid/hydroxyapatite composite for bone regeneration. Biomatter, 4 (1). e27664. ISSN 2159-2527

Gaharwar, A.K. and Mihaila, S.M. and Kulkarni, A.A. and Patel, A. and Di Luca, A. and Reis, R.L. and Gomes, M.E. and Blitterswijk, C.A. van and Moroni, L. and Khademhosseini, A. (2014) Amphiphilic Beads as Depots for Sustained Drug Release Integrated into Fibrillar Scaffolds. Journal of controlled release, 187 . 66 - 7.. ISSN 0168-3659

Georgi, N. and Cillero Pastor, B. and Eijkel, G. and Chinnagounder Periyasamy, P. and Kiss, A. and Blitterswijk, C.A. van and Post, J.N. and Heeren, R.M.A. and Karperien, H.B.J. (2014) Lipids as mediators of chondrogenesis. In: 2014 OARSI world congress on osteoarthritis, Paris, April 24-27, 2014, 24-04-2014 - 27-04-2014, Paris (pp. S46 - S48).

Georgi, Nicole and Blitterswijk, Clemens van and Karperien, Marcel (2014) MSC or chondrocyte seeded microcarriers as building blocks for cartilage tissue engineering. Tissue engineering. Part A, 20 (17-18). 2513 - 2523. ISSN 1937-3341

Harink, Björn and Gac, Severine Le and Baiao Barata, David and Blitterswijk, Clemens van and Habibovic, Pamela (2014) Microtiter plate-sized standalone chip holder for microenvironmental physiological control in gas-impermeable microfluidic devices. Lab on a Chip, 14 (11). pp. 1816-1820. ISSN 1473-0197

Hendrikson, W.J. and Blitterswijk, C.A. van and Verdonschot, N.J.J. and Moroni, L. and Rouwkema, J. (2014) Modeling mechanical signals on the surface of µCT and CAD based rapid prototype scaffold models to predict (early stage) tissue development. Biotechnology and bioengineering, 111 (9). 1864 - 1875. ISSN 0006-3592

Leferink, A.M. and Hendrikson, W.J. and Rouwkema, J. and Karperien, H.B.J. and Blitterswijk, C.A. van and Moroni, L. (2014) Increased cell seeding efficiency in bioplotted three-dimensional PEOT/PBT scaffolds. Journal of tissue engineering and regenerative medicine . ISSN 1932-6254

Leferink, A.M. and Schipper, D. and Arts, E. and Vrij, E.J. and Rivron, N.C. and Karperien, H.B.J. and Mittmann, K. and Blitterswijk, C.A. van and Moroni, L. and Truckenmuller, R.K. (2014) Engineered Micro-Objects as Scaffolding Elements in Cellular Building Blocks for Bottom-Up Tissue Engineering Approaches. Advanced materials, 26 (16). 2592 - 2599. ISSN 0935-9648

Leijten, Jeroen and Georgi, Nicole and Moreira Teixeira, Liliana and Blitterswijk, Clemens A. van and Post, Janine N. and Karperien, Marcel (2014) Metabolic programming of mesenchymal stromal cells by oxygen tension directs chondrogenic cell fate. Proceedings of the National Academy of Sciences of the United States of America, 111 (38). 13954 - 13959. ISSN 0027-8424

Masaeli, E. and Wieringa, P.A. and Morshed, M. and Nasr-Esfahani, M.H. and Sadri, S. and Blitterswijk, C.A. van and Moroni, L. (2014) Peptide functionalized polyhydroxyalkanoate nanofibrous scaffolds enhance Schwann cells activity. Nanomedicine : nanotechnology, biology and medicine, 10 (7). 1559 - 1569. ISSN 1748-6963

Portalska, K.K. and Moreira Teixeira, L.S. and Leijten, J.C.H. and Jin, R. and Blitterswijk, C.A. van and Boer, J. de and Karperien, H.B.J. (2014) Boosting angiogenesis and functional vascularization in injectable dextran-hyaluronic acid hydrogels by endothelial-like mesenchymal stromal cells. Tissue engineering. Part A, 20 (3-4). ISSN 1937-3341

Potier, E. and Rivron, N.C. and Blitterswijk, C.A. van and Ito, K. (2014) Micro-aggregates do not influence bone marrow stromal cell chondrogenesis. Journal of tissue engineering and regenerative medicine, in press . ISSN 1932-6254

Ribeiro, N and Sousa, S.R. and Blitterswijk, C.A. van and Moroni, L. and Monteiro, F.J. (2014) A biocomposite of collagen nanofibers and nanohydroxyapatite for bone regeneration. Biofabrication, 6 (3). 035015. ISSN 1758-5082

Zhang, J. and Luo, X. and Barbieri, D. and Barradas, A.M.C. and Bruijn, J.D. de and Blitterswijk, C.A. van and Yuan, H. (2014) Dimension of surface microstructure as an osteogenic factor in calcium phosphate ceramics. Acta biomaterialia, 10 (7). 3254 - 3263. ISSN 1742-7061

2013

Alves, H.A.D.C.R. and Mentink, A. and Le, B.Q. and Blitterswijk, C.A. van and Boer, J. de (2013) Effect of antioxidant supplementation on the total yield, oxidative stress levels and multipotency of bone marrow-derived human mesenchymal stromal cells. Tissue engineering. Part A, 19 (7-8). 928 - 937. ISSN 1937-3341

Barradas, A.M.C. and Monticone, V. and Hulsman, M. and Danoux, C.B.S.S. and Fernandes, H.A.M. and Tahmasebi Birgani, Z. and Barrere-de Groot, F.YF. and Yuan, H. and Reinders, M.J.T. and Habibovic, P. and Blitterswijk, C.A. van and Boer, J. de (2013) Molecular mechanisms of biomaterial-driven osteogenic differentiation in human mesenchymal stromal cells. Integrative biology, 5 (7). 920 - 931. ISSN 1757-9694

Barron, V. and Merghani, K. and Nandakumar, A. and Blitterswijk, C.A. van and Habibovic, P. and Shaw, G. and Coleman, C. and Hayes, J. and Moroni, L. and Barry, F. and Murphy, M. (2013) Cartilage repair in an osteochondral defect in a rabbit model. Osteoarthritis and cartilage, 21 (supplement). S120 - S120. ISSN 1063-4584

Bartha, L. and Hamann, D. and Pieper, J. and Peters, F. and Riesle, J. and Vajda, A. and Kaposi-Novak, P. and Rudolf-Hangody, L. and Vasarhelyi, G. and Bodo, L. and Blitterswijk, C.A. van and Wijn, J.R. de and Kenyeres, A. and Modis, L. and Balo, E. and Hangody, L. (2013) A clinical feasibility study to evaluate the safety and efficacy of PEOT/PBT implants for human donor site filling during mosaicplasty. European journal of orthopaedic surgery and traumatology, 23 (1). 81 - 91. ISSN 1633-8065

Buitinga, M. and Truckenmüller, R.K. and Engelse, M.A. and Moroni, L. and Hoopen, H.W.M. ten and Blitterswijk, C.A. van and Koning, E.J.P. de and Apeldoorn, A.A. van and Karperien, H.B.J. (2013) Microwell Scaffolds for the Extrahepatic Transplantation of Islets of Langerhans. PLOS one, 8 (5). e64772 - e64782. ISSN 1932-6203

Chatterjea-Ganguly, A.A. and Yuan, H. and Fennema, E.M. and Chatterjea, S. and Garritsen, H.S.P. and Renard, A. and Blitterswijk, C.A. van and Boer, J. de (2013) Engineering new bone via a minimally invasive route using human bone marrow derived stromal cell aggregates, micro ceramic particles and human platelet rich plasma gel. Tissue engineering. Part A, 19 (3-4). 340 - 349. ISSN 1937-3341

Chen, H. and Truckenmuller, R.K. and Blitterswijk, C.A. van and Moroni, L. (2013) Fabrication of nanofibrous scaffolds for tissue engineering applications. In: Nanomaterials in tissue engineering: Fabrication and applications. Series in Biomaterials (56). Woodhead Publishing, 158 - 182. ISBN 9780857095961

Cranford, S.W. and Boer, J. de and Blitterswijk, C.A. van and Buehler, M.J. (2013) Materiomics: An -omics Approach to Biomaterials Research. Advanced materials, 25 (6). 802 - 824. ISSN 0935-9648

Doorn, J. and Fernandes, H.A.M. and Le, B.Q. and Peppel, J. van de and Leeuwen, J.P.T.M. van and Vries, M.R. de and Aref, Z. and Quax, P.H.A. and Myklebost, O. and Saris, D.B.F. and Blitterswijk, C.A. van and Boer, J. de (2013) A small molecule approach to engineering vascularized tissue. Biomaterials, 34 (12). 3053 - 3063. ISSN 0142-9612

Doorn, J. and Roberts, S.J. and Hilderink, J. and Groen, N. and Apeldoorn, A.A. van and Blitterswijk, C.A. van and Schrooten, J. and Boer, J. de (2013) Insulin-like-growth-factor-I enhances proliferation and differentiation of human mesenchymal stromal cells in vitro. Tissue engineering. Part A, 19 (15-16). 1817 - 1828. ISSN 1937-3341

Fennema, E.M. and Rivron, N.C. and Rouwkema, J. and Blitterswijk, C.A. van and Boer, J. de (2013) Spheroid culture as a tool for creating 3D complex tissues. Trends in Biotechnology, 31 (2). 108 - 115. ISSN 0167-7799

Georgi, N. and Taipaleenmaki, H. and Wijnen, A. van and Groen, N. and Janaeczek-Portalska, K. and Blitterswijk, C.A. van and Boer, J. de and Post, J.N. and Karperien, H.B.J. (2013) MicroRNAs are prognostic markers for the chondrogenic potential of MSCs. Osteoarthritis and cartilage, 21 (Suppl.). S31 - S32. ISSN 1063-4584

Groen, N. and Cranford, S.W. and Boer, J. de and Buehler, M.J. and Blitterswijk, C.A. van (2013) Introducing Materiomics. In: Materiomics - High-Throughput Screening of Biomaterial Properties. Cambridge University Press, Chapter 1 - . ISBN 9781107016774

Groen, N. and Peppel, J. van de and Yuan, H. and Leeuwen, J.P.T.M. van and Blitterswijk, C.A. van and Boer, J. de (2013) Bioinformatics-based selection of a model cell type for in vitro biomaterial testing. Biomaterials, 34 (22). 5552 - 5561. ISSN 0142-9612

Harink, M.B.M. and Gac, S. le and Truckenmüller, R.K. and Blitterswijk, C.A. van and Habibovic, P. (2013) Regeneration-on-a-chip? The perspectives on use of microfluidics in regenerative medicine. Lab on a chip, 13 (18). pp. 3512-3528. ISSN 1473-0197

Hendriks, J.A.A. and Moroni, L. and Riesle, J.U. and Wijn, J.R. de and Blitterswijk, C.A. van (2013) The effect of scaffold-cell entrapment capacity and physico-chemical properties on cartilage regeneration. Biomaterials, 34 (17). 4259 - 4265. ISSN 0142-9612

Higuera Sierra, G.A. and Hendriks, J.A. and Dalum, J. van and Wu, L. and Schotel, R. and Moreira Teixeira, L.S. and Doel, M. van den and Leijten, J.C.H. and Riesle, J. and Karperien, H.B.J. and Blitterswijk, C.A. van and Moroni, L. (2013) In vivo screening of extracellular matrix components produced under multiple experimental conditions implanted in one animal. Integrative biology, 2013 (6). 889 - 898. ISSN 1757-9694

Hilderink, J. and Otto, C. and Slump, C.H. and Lenferink, A.T.M. and Engelse, M.A. and Blitterswijk, C.A. van and Koning, E.J.P. de and Karperien, H.B.J. and Apeldoorn, A.A. van (2013) Label-Free Detection of Insulin and Glucagon within Human Islets of Langerhans Using Raman Spectroscopy. PLoS ONE, 8 (10). e78148. ISSN 1932-6203

Klein Gunnewiek, Michel and Benetti, Edmondo M. and Di Luca, Andrea and Blitterswijk, Clemens A. van and Moroni, Lorenzo and Vancso, G. Julius (2013) Thin Polymer Brush Decouples Biomaterial's Micro-/Nano-Topology and Stem Cell Adhesion. Langmuir, 29 (45). 13843 - 13852. ISSN 0743-7463

Kunstar, A. and Leferink, A.M. and Okagbare, P.I. and Morris, M.D. and Roessler, B.J. and Otto, C. and Karperien, H.B.J. and Blitterswijk, C.A. van and Moroni, L. and Apeldoorn, A.A. van (2013) Label-free Raman monitoring of extracellular matrix formation in three-dimensional polymeric scaffolds. Journal of the Royal Society. Interface, 10 (86). p. 20130464. ISSN 1742-5689

Landman, E.B.M. and Miclea, R.L. and Blitterswijk, C.A. van and Karperien, H.B.J. (2013) Small molecule inhibitors of WNT/beta-catenin signaling block IL1beta/TNFalpha induced cartilage degradation. Arthritis research & therapy, 15 (4). 1 - 11. ISSN 1478-6354

Leijten, J.C.H. and Georgi, N. and Wu, L. and Blitterswijk, C.A. van and Karperien, H.B.J. (2013) Cell sources for articular cartilage repair strategies: shifting from mono-cultures to co-cultures. Tissue engineering. Part B: Reviews, 19 (1). 31 - 40. ISSN 1937-3368

Leijten, Jeroen C.H. and Bos, Steffan D. and Landman, Ellie B.M. and Georgi, Nicole and Jahr, Holger and Meulenbelt, Ingrid and Post, Janine N. and Blitterswijk, Clemens A. van and Karperien, Marcel (2013) GREM1, FRZB and DKK1 mRNA levels correlate with osteoarthritis and are regulated by osteoarthritis associated factors. Arthritis research & therapy, 15 (5). 1 - 11. ISSN 1478-6354

Liu, J. and Hilderink, J. and Groothuis, T.A.M. and Otto, C. and Blitterswijk, C.A. van and Boer, J. de (2013) Monitoring nutrient transport in tissue-engineered grafts. Journal of tissue engineering and regenerative medicine . ISSN 1932-6254

Lucassen, C. and Blitterswijk, C.A. van (2013) De ‘Tubantia-regel’ als richtsnoer in zaken. Het Financieele Dagblad . 2 - . ISSN 1388-4425

Ma, B. and Leijten, J.C.H. and Wu, L. and Kip, M. and Blitterswijk, C.A. van and Post, J.N. and Karperien, H.B.J. (2013) Gene expression profiling of dedifferentiated human articular chondrocytes in monolayer culture. Osteoarthritis and cartilage, 21 (4). 599 - 603. ISSN 1063-4584

Ma, B. and Zhong, L. and Blitterswijk, C.A. van and Post, J.N. and Karperien, H.B.J. (2013) TCF4 is a pro-catabolic and apoptotic factor in human articular chondrocytes by potentiating NF-κB signaling. Journal of biological chemistry, 288 . 17552 - 17558. ISSN 0021-9258

Masaeli, E. and Morshed, M. and Hossein Nasr-Esfahani, M. and Sadri, S. and Hilderink, J. and Apeldoorn, A.A. van and Blitterswijk, C.A. van and Moroni, L. (2013) Fabrication, Characterization and Cellular Compatibility of Poly(Hydroxy Alkanoate) Composite Nanofibrous Scaffolds for Nerve Tissue Engineering. PLOS one, 8 (2). 1 - 13. ISSN 1932-6203

Mentink, A. and Hulsman, M. and Groen, N. and Licht, R. and Dechering, K.J. and Stok, J. van der and Alves, H.A.D.C.R. and Dhert, W.J.A. and Someren, E.P. van and Reinders, M.J.T. and Blitterswijk, C.A. van and Boer, J. de (2013) Predicting the therapeutic efficacy of MSC in bone tissue engineering using the molecular marker CADM1. Biomaterials, 34 (19). 4592 - 4601. ISSN 0142-9612

Moroni, L. and Nandakumar, A. and Barrère, F. and Blitterswijk, C.A. van and Habibovic, P. (2013) Plug and play: combining materials and technologies to improve bone regenerative strategies. Journal of tissue engineering and regenerative medicine . ISSN 1932-6254

Nandakumar, A. and Barradas, A.M.C. and Boer, J. de and Moroni, L. and Blitterswijk, C.A. van and Habibovic, P. (2013) Combining technologies to create bioactive hybrid scaffolds for bone tissue engineering. Biomatter, 3 (2). 1 - 13. ISSN 2159-2527

Nandakumar, A. and Cruz, C. and Mentink, A. and Tahmasebi Birgani, Z. and Moroni, L. and Blitterswijk, C.A. van and Habibovic, P. (2013) Monolithic and assembled polymer-ceramic composites for bone regeneration. Acta biomaterialia, 9 (3). 5708 - 5717. ISSN 1742-7061

Nandakumar, A. and Tahmasebi Birgani, Z. and Reis Santos, D. and Mentink, A. and Auffermann, N. and Werf, K.O. van der and Bennink, M.L. and Moroni, L. and Blitterswijk, C.A. van and Habibovic, P. (2013) Surface modification of electrospun fibre meshes by oxygen plasma for bone regeneration. Biofabrication, 5 (1). 015006. ISSN 1758-5082

Nandakumar, A. and Truckenmuller, R.K. and Ahmed, M. and Damanik, F. and Santos, D.R. and Auffermann, N. and Boer, J. de and Habibovic, P. and Blitterswijk, C.A. van and Moroni, L. (2013) Electrospinning: A Fast Process for Imprinting Micro and Nano Patterns on Electrospun Fiber Meshes at Physiological Temperatures. Small, 9 (20). 3405 - 3409. ISSN 1613-6810

Portalska, K.K. and Groen, N. and Krenning, G. and Georgi, N. and Mentink, A. and Harmsen, M.C. and Blitterswijk, C.A. van and Boer, J. de (2013) The effect of donor variation and senescence on endothelial differentiation of human mesenchymal stromal cells. Tissue engineering. Part A, 19 (21-22). 2318 - 2329. ISSN 1937-3341

Portalska-Janeczek, K.K. and Chamberlain, M.D. and Lo, C and Blitterswijk, C.A. van and Sefton, M.V. and Boer, J. de (2013) Collagen modules for in situ delivery of mesenchymal stromal cell-derived endothelial cells for improved angiogenesis. Journal of tissue engineering and regenerative medicine . ISSN 1932-6254

Prins, H.J. and Fernandes, H.A.M. and Rozemuller, H. and Blitterswijk, C.A. van and Boer, J. de and Martens, ACM (2013) Spatial distribution and survival of human and goat mesenchymal stromal cells on hydroxyapatite and β-tricalcium phosphate. Journal of tissue engineering and regenerative medicine . ISSN 1932-6254

Silva, J.M. and Georgi, N. and Costa, R. and Sher, P. and Reis, R.L. and Blitterswijk, C.A. van and Karperien, H.B.J. and Mano, J.F. (2013) Nanostructured 3D Constructs Based on Chitosan and Chondroitin Sulphate Multilayers for Cartilage Tissue Engineering. PLOS one, 8 (2). e55451. ISSN 1932-6203

Song, G. and Habibovic, P. and Bao, C. and Hu, J. and Blitterswijk, C.A. van and Yuan, H. and Chen, W. and Xu, H.H.K. (2013) The homing of bone marrow MSCs to non-osseous sites for ectopic bone formation induced by osteoinductive calcium phosphate. Biomaterials, 34 (9). 2167 - 2176. ISSN 0142-9612

Spitters, T.W.G.M. and Leijten, J.C.H. and Deus, F.D. and Costa, I.B.F. and Apeldoorn, A.A. van and Blitterswijk, C.A. van and Karperien, H.B.J. (2013) A dual flow bioreactor with controlled mechanical stimulation for cartilage tissue engineering. Tissue engineering. Part C: Methods, 19 (10). 774 - 783. ISSN 1937-3384

Sui, X. and Feng, X. and Di Luca, A. and Blitterswijk, C.A. van and Moroni, L. and Hempenius, M.A. and Vancso, G.J. (2013) Poly(N-isopropylacrylamide)–poly(ferrocenylsilane) dual-responsive hydrogels: synthesis, characterization and antimicrobial applications. Polymer chemistry, 4 (2). 337 - 342. ISSN 1759-9954

Thakkar, S. and Ghebes, C.A. and Ahmed, M. and Kelder, C. and Blitterswijk, C.A. van and Saris, D.B.F. and Fernandes, H.A.M. and Moroni, L. (2013) Mesenchymal stromal cell-derived extracellular matrix influences gene expression of chondrocytes. Biofabrication, 5 (2). 025003. ISSN 1758-5082

Unadkat, H.V. and Gauvin, R. and Blitterswijk, C.A. van and Khademhosseini, A. and Boer, J. de and Truckenmüller, R.K. (2013) Microfabrication techniques in materiomics. In: Materiomics - High-Throughput Screening of Biomaterial Properties. Cambridge University Press, Chapter 4 - . ISBN 9781107016774

Unadkat, H.V. and Groen, N. and Doorn, J. and Fischer, B. and Barradas, A.M.C. and Hulsman, M. and Peppel, J. van de and Moroni, L. and Leeuwen, J. van and Reinders, M.J.T. and Blitterswijk, C.A. van and Boer, J. de (2013) High content imaging in the screening of biomaterial-induced MSC behavior. Biomaterials, 34 (5). 1498 - 1505. ISSN 0142-9612

Unadkat, H.V. and Rewagad, R.R. and Hulsman, M. and Hulshof, G.F.B. and Truckenmüller, R.K. and Stamatialis, D. and Reinders, M.J.T. and Eijkel, J.C.T. and Berg, A. van den and Blitterswijk, C.A. van and Boer, J. de (2013) A modular versatile chip carrier for high-throughput screening of cell–biomaterial interactions. Journal of the Royal Society Interface, 10 (78). p. 20120753. ISSN 1742-5689

Wu, Ling and Leijten, Jeroen and Blitterswijk, Clemens A. van and Karperien, Marcel (2013) Fibroblast growth factor-1 is a mesenchymal stromal cell-secreted factor stimulating proliferation of osteoarthritic chondrocytes in co-culture. Stem cells and development, 22 (17). 2356 - 2367. ISSN 1547-3287

Zeng, X. and Hendrikson, W.J. and Yan, J. and Rouwkema, J. and Blitterswijk, C.A. van and Moroni, Lorenzo and Heide, E. van der (2013) The effect of material, structure and cell culture on the tribological performance of 3D porous scaffold for functional tissue regeneration. In: Proceedings of 5th World Tribology Conference, 08-09-2013 - 13-09-2013, Turino, Italy.

2012

Alves, H.A.D.C.R. and Ginkel, J. van and Groen, N. and Hulsman, M. and Mentink, A. and Reinders, M.J.T. and Blitterswijk, C.A. van and Boer, J. de (2012) A Mesenchymal Stromal Cell Gene Signature for Donor Age. PLOS one, 7 (8). 1 - 11. ISSN 1932-6203

Barradas, A.M.C. and Lachmann, K. and Hlawacek, G. and Frielink, C. and Truckenmuller, R.K. and Boerman, O.C. and Gastel, R. van and Garritsen, H.S.P. and Thomas, M. and Moroni, L. and Blitterswijk, C.A. van and Boer, J. de (2012) Surface modifications by gas plasma control osteogenic differentiation of MC3T3-E1 cells. Acta biomaterialia, 8 (8). 2969 - 2977. ISSN 1742-7061

Barradas, A.M.C. and Yuan, H. and Stok, J. van der and Le, B.Q. and Fernandes, H.A.M. and Ganguly, A.A. and Hogenes, M.C.H. and Schultz, K. and Rae Donahue, L. and Blitterswijk, C.A. van and Boer, J. de (2012) The influence of genetic factors on the osteoinductive potential of calcium phosphate ceramics in mice. Biomaterials, 33 (23). 5696 - 5705. ISSN 0142-9612

Barron, V. and Merghani, K. and Moroni, L. and Nandakumar, A. and Habibovic, P. and Shaw, G. and Coleman, C. and Blitterswijk, C.A. van and Barry, F. and Murphy, M. (2012) Towards a chondromimetic scaffold for cartilage repair. In: 3rd TERMIS World Congress 2012 (pp. 71 - 71).

Blitterswijk, C.A. van (2012) Creativiteit en de financiering. Weekblad Elsevier, 68 (23). 52 - 52. ISSN 0922-3444

Blitterswijk, C.A. van (2012) Cellen temmen met slimme klei. Medisch Contact, 67 (23). 1397 - 1399. ISSN 0025-8245

Blitterswijk, C.A. van and Engelenburg, H. (2012) Nederland barst van de wetenschappelijke kennis maar krijgt de commercialisatie ervan niet op gang. Het financiele dagblad .

Buckland, J. and Leijten, J.C.H. and Blitterswijk, C.A. van and Karperien, H.B.J. (2012) Osteoarthritis: Control of human cartilage hypertrophic differentiation. Research highlight van: Gremlin1, frizzled-related protein, and Dkk-1 are key regulators of human articular cartilage homeostasis. Nature reviews rheumatology, 8 (7). 368 - . ISSN 1759-4790

Catros, S. and Guillemont, F. and Nandakumar, A. and Ziane, S. and Moroni, L. and Habibovic, P. and Blitterswijk, C.A. van and Rousseau, B. and Chassande, O. and Amedee, J. and Fricain, J-C. (2012) Layer-by-layer tissue microfabrication supports cell proliferation in vitro and in vivo. Tissue engineering. Part C: Methods, 18 (1). 1 - 9. ISSN 1937-3384

Chatterjea, A. and Renard, A.J.S. and Jolink, C. and Blitterswijk, C.A. van and Boer, J. de (2012) Streamlining the generation of an osteogenic graft by 3D culture of unprocessed bone marrow on ceramic scaffolds. Journal of tissue engineering and regenerative medicine, 6 (2). 103 - 112. ISSN 1932-6254

Cravo Barradas, A.M. and Fernandes, H.A.M. and Groen, N. and Chai, Y.C. and Schrooten, J. and Peppel, J. van de and Leeuwen, J.P.T.M. van and Blitterswijk, C.A. van and Boer, J. de (2012) A calcium-induced signaling cascade leading to osteogenic differentiation of human bone marrow-derived mesenchymal stromal cells. Biomaterials, 33 (11). 3205 - 3215. ISSN 0142-9612

Doorn, J. and Leusink, Maarten and Groen, N. and Peppel, J. van de and Leeuwen, J.P.T.M. van and Blitterswijk, C.A. van and Boer, J. de (2012) Diverse effects of cyclic AMP variants on osteogenic and adipogenic differentiation of human mesenchymal stromal cells. Tissue engineering. Part A, 18 (13-14). 1431 - 1442. ISSN 1937-3341

Doorn, J. and Moll, G. and Blanc, K. le and Blitterswijk, C.A. van and Boer, J. de (2012) Therapeutic Applications of Mesenchymal Stromal Cells: Paracrine Effects and Potential Improvements. Tissue engineering. Part B: Reviews, 18 (2). 101 - 116. ISSN 1937-3368

Doorn, J. and Siddappa, R. and Blitterswijk, C.A. van and Boer, J. de (2012) Forskolin enhances in vivo bone formation by human mesenchymal stromal cells. Tissue engineering. Part A, 18 (5-6). 558 - 567. ISSN 1937-3341

Higuera, G. and Schop, D. and Spitters, T.W.G.M. and Dijkhuizen-Radersma, R. van and Bracke, M. and Bruijn, J.D. de and Martens, D.E. and Karperien, H.B.J. and Boxtel, A.J.B. van and Blitterswijk, C.A. van (2012) Patterns of amino Acid metabolism by proliferating human mesenchymal stem cells. Tissue engineering. Part A, 18 (5-6). 654 - 664. ISSN 1937-3341

Higuera Sierra, G.A. and Boxtel, A.J.B. van and Blitterswijk, C.A. van and Moroni, L. (2012) The physics of tissue formation with mesenchymal stem cells. Trends in Biotechnology, 30 (11). 583 - 590. ISSN 0167-7799

Higuera Sierra, G.A. and Moroni, L. and Blitterswijk, C.A. van (2012) High troughput multiwell system for culturing 3D tissue constructs in-vitro or in-vivo, method for producing said multiwell system and methods and methods or preparing 3D tissue constructs from cells using said multiwell system. Patent.

Klein Gunnewiek, M. and Di Luca, A. and Sui, X. and Blitterswijk, C.A. van and Moroni, L. and Vancso, G.J. (2012) Controlled surface initiated polymerization of N-isopropylacrylamide from polycaprolactone substrates for regulating cell attachment and detachment. Israel journal of chemistry, 52 (3-4). 339 - 346. ISSN 0021-2148

Kunstar, A. and Leijten, J.C.H. and Leuveren, S. van and Hilderink, J. and Otto, C. and Blitterswijk, C.A. van and Karperien, H.B.J. and Apeldoorn, A.A. van (2012) Recognizing different tissues in human fetal femur cartilage by label-free Raman microspectroscopy. Journal of biomedical optics, 17 (11). p. 116012. ISSN 1083-3668

Leijten, J.C.H. and Emons, J. and Sticht, C. and Gool, S. van and Decker, E. and Uitterlinden, A. and Rappold, G. and Hofman, A. and Rivadeneira, F. and Scherjon, S. and Wit, J.M. and Meurs, J. van and Blitterswijk, C.A. van and Karperien, H.B.J. (2012) Gremlin 1, Frizzled-related protein, and Dkk-1 are key regulators of human articular cartilage homeostasis. Arthritis & rheumatism, 64 (10). 3302 - 3312. ISSN 0004-3591

Leijten, J.C.H. and Emons, J. and Sticht, C. and Gool, S. van and Decker, E. and Uitterlinden, A. and Rappold, G. and Hofman, A. and Rivadeneira, F. and Scherjon, S. and Wit, J.M. and Meurs, J. van and Blitterswijk, C.A. van and Karperien, H.B.J. (2012) Gremlin 1, frizzled-related protein, and Dkk-1 are key regulators of human articular cartilage homeostasis: Article recommendation on F1000Prime. .

Leijten, J.C.H. and Moreira Teixeira, L.S. and Landman, E.B.M. and Blitterswijk, C.A. van and Karperien, H.B.J. (2012) Hypoxia Inhibits Hypertrophic Differentiation and Endochondral Ossification in Explanted Tibiae. PLOS one, 7 (11). 1 - 7. ISSN 1932-6203

Lourenco, B.N. and Marchioli, G. and Song, W and Reis, R.L. and Blitterswijk, C.A. van and Karperien, H.B.J. and Apeldoorn, A.A. van and Mano, J.F. (2012) Wettability influences cell behavior on superhydrophobic surfaces with different topographies. Biointerphases, 7 (46). 1 - 11. ISSN 1934-8630

Ma, B. and Blitterswijk, C.A. van and Karperien, H.B.J. (2012) A Wnt/ß-catenin negative feedback loop inhibits IL-1-induced MMP expression in human articular chondrocytes. Arthritis and rheumatism, 64 . 2589 - 2600. ISSN 0004-3591

Ma, B. and Blitterswijk, C.A. van and Karperien, H.B.J. (2012) A Wnt/β-catenin negative feedback loop inhibits interleukin-1–induced matrix metalloproteinase expression in human articular chondrocytes. Arthritis & rheumatism, 64 (8). 2589 - 2600. ISSN 1529-0131

Moreira Teixeira, L.S. and Bijl, S. and Pully, V.V. and Otto, C. and Jin, R. and Feijen, J. and Blitterswijk, C.A. van and Dijkstra, P.J. and Karperien, H.B.J. (2012) Self-attaching and cell-attracting in-situ forming dextran-tyramine conjugates hydrogels for arthroscopic cartilage repair. Biomaterials, 33 (11). 3164 - 3174. ISSN 0142-9612

Moreira Teixeira, L.S. and Feijen, J. and Blitterswijk, C.A. van and Dijkstra, P.J. and Karperien, H.B.J. (2012) Enzyme-catalyzed crosslinkable hydrogels: Emerging strategies for tissue engineering. Biomaterials, 33 (5). 1281 - 1290. ISSN 0142-9612

Moreira Teixeira, L.S. and Leijten, J.C.H. and Sobral, J. and Jin, R. and Apeldoorn, A.A. van and Feijen, J. and Blitterswijk, C.A. van and Dijkstra, P.J. and Karperien, H.B.J. (2012) High throughput generated micro-aggregates of chondrocytes stimulate cartilage formation in vitro and in vivo. European cells & materials, 23 . 387 - 399. ISSN 1473-2262

Moreira Teixeira, L.S. and Leijten, J.C.H. and Wennink, J.W.H. and Chatterjea, A. and Feijen, J. and Blitterswijk, C.A. van and Dijkstra, P.J. and Karperien, M. (2012) The effect of platelet lysate supplementation of a dextran-based hydrogel on cartilage formation. Biomaterials, 33 (14). 3651 - 3661. ISSN 0142-9612

Moroni, L. and Boxtel, A.J.B. van and Blitterswijk, C.A. van and Higuera Sierra, G.A. (2012) 420 A Platform of Porous Biomaterials as 3D Culture Systems for Cancer Biology. In: 22nd Biennial Congress of the European Association for Cancer Research, 07-07-2012 - 12-07-2012 (pp. S102 -).

Portalska-Janeczek, K.K. and Leferink, A.M. and Groen, N. and Fernandes, H.A.M. and Moroni, L. and Blitterswijk, C.A. van and Boer, J. de (2012) Endothelial Differentiation of Mesenchymal Stromal Cells. PLOS one, 7 (10). 1 - 16. ISSN 1932-6203

Rivron, N.C. and Raiss, C.C. and Liu, J. and Nandakumar, A. and Sticht, C. and Gretz, N. and Truckenmuller, R.K. and Rouwkema, J. and Blitterswijk, C.A. van (2012) Sonic Hedgehog-activated engineered blood vessels enhance bone tissue formation. Proceedings of the National Academy of Sciences of the United States of America, 109 (12). 4413 - 4418. ISSN 0027-8424

Rivron, Nicolas C. and Vrij, Erik J. and Rouwkema, Jeroen and Le Gac, Severine and Berg, Albert van den and Truckenmuller, Roman K. and Blitterswijk, Clemens A. van (2012) Tissue deformation spatially modulates VEGF signaling and angiogenesis. Proceedings of the National Academy of Sciences of the United States of America, PNAS, 109 (18). pp. 6886-6891. ISSN 0027-8424

Samal, S.K. and Dash, M. and Vlierberghe, S. van and Kaplan, D. and Chiellini, E. and Blitterswijk, C.A. van and Moroni, L. and Dubruel, P. (2012) Cationic polymers and their therapeutic potential. Chemical Society reviews, 41 . 7147 - 7194. ISSN 0306-0012

Tahmasebi Birgani, Z. and Blitterswijk, C.A. van and Habibovic, P. (2012) Strontium incorporation into calcium-phosphate ceramic coatings. In: 3rd TERMIS World Congress 2012, 05-09-2012 - 08-09-2012 (pp. 198 - 198).

Truckenmüller, R.K. and Giselbrecht, S. and Escalante, M. and Groenendijk, M.N.W. and Papenburg, B.J. and Rivron, N.C. and Unadkat, H.V. and Saile, V. and Subramaniam, V. and Blitterswijk, C.A. van and Wessling, M. and Boer, J. de and Stamatialis, D. (2012) Fabrication of cell container arrays with overlaid surface topographies. Biomedical microdevices, 14 (1). 95 - 107. ISSN 1387-2176

Wu, L. and Prins, H.J. and Helder, M. and Blitterswijk, C.A. van and Karperien, H.B.J. (2012) Trophic Effects of Mesenchymal Stem Cells in Chondrocyte Co-Cultures are Independent of Culture Conditions and Cell Sources. Tissue engineering. Part A, 18 (15-16). 1542 - 1551. ISSN 1937-3341

2011

Alves, Hugo and Dechering, Koen and Blitterswijk, Clemens van and Boer, Jan de (2011) High-Throughput Assay for the Identification of Compounds Regulating Osteogenic Differentiation of Human Mesenchymal Stromal Cells. PloS One, 6 (10). e26678. ISSN 1932-6203

Barradas, Ana M.C. and Yuan, Huipin and Blitterswijk, Clemens A. van and Habibovic, Pamela (2011) Osteoinductive biomaterials: current knowledge of properties, experimental models and biological mechanisms. European Cells & Materials, 21 . pp. 407-429. ISSN 1473-2262

Bettahalli, N.M.S. and Vicente, J. and Moroni, L. and Higuera, G.A. and Blitterswijk, C.A. van and Wessling, M. and Stamatialis, D.F. (2011) Integration of hollow fiber membranes improves nutrient supply in three-dimensional tissue constructs. Acta Biomaterialia, 7 (9). pp. 3312-3324. ISSN 1742-7061

Both, Sanne K. and Apeldoorn, Aart A. van and Jukes, Jojanneke M. and Englund, Mikael C.O. and Hyllner, Johan and Blitterswijk, Clemens A. van and Boer, Jan de (2011) Differential bone-forming capacity of osteogenic cells from either embryonic stem cells or bone marrow-derived mesenchymal stem cells. Journal of Tissue Engineering and Regenerative Medicine, 5 (3). pp. 180-190. ISSN 1932-6254

Correia, Clara R. and Moreira Teixeira, Liliana S. and Moroni, Lorenzo and Reis, Rui L. and Blitterswijk, Clemens A. van and Karperien, Marcel and Mano, João F. (2011) Chitosan Scaffolds Containing Hyaluronic Acid for Cartilage Tissue Engineering. Tissue Engineering. Part C: methods, 17 (7). pp. 717-730. ISSN 1937-3384

Doorn, Joyce and Peppel, Jeroen van de and Leeuwen, Johannes P.T.M. van and Groen, Nathalie and Blitterswijk, Clemens A. van and Boer, Jan de (2011) Pro-osteogenic trophic effects by PKA activation in human mesenchymal
stromal cells.
Biomaterials, 32 (26). pp. 6089-6098. ISSN 0142-9612

Giselbrecht, Stefan and Reinhardt, Martina and Mappes, Timo and Börner, Martin and Gottwald, Eric and Blitterswijk, Clemens van and Saile, Volker and Truckenmüller, Roman (2011) Closer to nature – bio-inspired patterns by transforming latent lithographic images. Advanced Materials, 23 (42). pp. 4873-4879. ISSN 0935-9648

Jin, Rong and Moreira Teixeira, Liliana S. and Dijkstra, Pieter J. and Blitterswijk, Clemens A. van and Karperien, Marcel and Feijen, Jan (2011) Chondrogenesis in injectable enzymatically crosslinked heparin/dextran hydrogels. Journal of Controlled Release, 152 (1). pp. 186-195. ISSN 0168-3659

Kunstar, Aliz and Otto, Cees and Karperien, Marcel and Blitterswijk, Clemens van and Apeldoorn, Aart van (2011) Raman Microspectroscopy: A Noninvasive Analysis Tool for Monitoring of Collagen-Containing Extracellular Matrix Formation in a Medium-Throughput Culture System. Tissue Engineering. Part C: methods, 17 (7). pp. 737-744. ISSN 1937-3384

Neves, Sara C. and Moreira Teixeira, Liliana S. and Moroni, Lorenzo and Reis, Rui L. and Blitterswijk, Clemens A. van and Alves, Natália M. and Karperien, Marcel and Mano, João F. (2011) Chitosan/Poly(ɛ-caprolactone) blend scaffolds for cartilage repair. Biomaterials, 32 (4). pp. 1068-1079. ISSN 0142-9612

Truckenmuller, Roman and Giselbrecht, Stefan and Rivron, Nicolas and Gottwald, Eric and Saile, Volker and Berg, Albert van den and Wessling, Matthias and Blitterswijk, Clemens van (2011) Thermoforming of Film-Based Biomedical Microdevices. Advanced Materials, 23 (11). pp. 1311-1329. ISSN 0935-9648

Unadkat, Hemant V and Hulsman, Marc and Cornelissen, Kamiel and Papenburg, Bernke J. and Truckenmuller, Roman K. and Post, Gerhard F. and Uetz, Marc and Reinders, Marcel J.T. and Blitterswijk, Clemens A. van and Stamatialis, Dimitrios and Boer, Jan de (2011) An algorithm-based topographical biomaterials library to instruct cell fate. Proceedings of the National Academy of Sciences of the United States of America, PNAS, 108 (40). pp. 16565-16570. ISSN 0027-8424

Wilson, C.E. and Blitterswijk, C.A. van and Verbout, A.J. and Dhert, W.J.A. and Bruijn, J.D. de (2011) Scaffolds with a standardized macro-architecture fabricated from several calcium phosphate ceramics using an indirect rapid prototyping technique. Journal of Materials Science: Materials in Medicin, 22 (1). pp. 97-105. ISSN 0957-4530

Wu, Ling and Leijten, Jeroen C.H. and Georgi, Nicole and Post, Janine N. and Blitterswijk, Clemens A. van and Karperien, Marcel (2011) Trophic Effects of Mesenchymal Stem Cells Increase Chondrocyte Proliferation and Matrix Formation. Tissue Engineering. Part A, 17 (9-10). pp. 1425-1436. ISSN 1937-3341

Yuan, Huipin and Fernandes, Hugo and Habibovic, Pamela and Boer, Jan de and Barradas, Ana M.C. and Ruiter, Ad de and Walsh, William R. and Blitterswijk, Clemens A. van and Bruijn, Joost D. de (2011) 'Smart' biomaterials and osteoinductivity. Nature Reviews Rheumatology, 7 . c1 - . ISSN 1759-4790

2010

Alves, Hugo and Munoz-Najar, Ursula and Wit, Jan de and Renard, Auke J.S. and Hoeijmakers, Jan H.J. and Sedivy, John M. and Blitterswijk, Clemens van and Boer, Jan de (2010) A link between the accumulation of DNA damage and loss of multi-potency of human mesenchymal stromal cells. Journal of cellular and molecular medicine, 14 (12). pp. 2729-2738. ISSN 1582-1838

Bat, Erhan and Kothman, Bas H.M. and Higuera Sierra, Gustavo Andrés and Blitterswijk, Clemens A. van and Feijen, Jan and Grijpma, Dirk W. (2010) Ultraviolet light crosslinking of poly(trimethylene carbonate) for elastomeric tissue engineering scaffolds. Biomaterials, 31 (33). pp. 8696-8705. ISSN 0142-9612

Chatterjea, Anindita and Meijer, Gert and Blitterswijk, Clemens van and Boer, Jan de (2010) Clinical Application of Human Mesenchymal Stromal Cells for Bone Tissue Engineering. Stem cells international, 2010 (215625). ISSN 1687-9678

Fernandes, Hugo and Mentink, Anouk and Bank, Ruud and Stoop, Reinout and Blitterswijk, Clemens van and Boer, Jan de (2010) Endogenous Collagen Influences Differentiation of Human Multipotent Mesenchymal Stromal Cells. Tissue Engineering. Part A, 16 (5). pp. 1693-1702. ISSN 1937-3341

Gaalen, Steven M. van and Bruijn, Joost D. de and Wilson, Clayton E. and Blitterswijk, Clemens A. van and Verbout, Abraham J. and Alblas, Jacqueline and Dhert, Wouter J.A. (2010) Relating cell proliferation to in vivo bone formation in porous Ca/P scaffolds. Journal of biomedical materials research. Part A, 92 (1). pp. 303-310. ISSN 1549-3296

Habibovic, Pamela and Juhl, Maria V. and Clyens, Stuart and Martinetti, Roberta and Dolcini, Laura and Theilgaard, Naseem and Blitterswijk, Clemens A. van (2010) Comparison of two carbonated apatite ceramics in vivo. Acta Biomaterialia, 6 (6). pp. 2219-2226. ISSN 1742-7061

Hendriks, Jeanine A.A. and Miclea, Razvan L. and Schotel, Roka and Bruijn, Ewart de and Moroni, Lorenzo and Karperien, Marcel and Riesle, Jens and Blitterswijk, Clemens A. van (2010) Primary chondrocytes enhance cartilage tissue formation upon co-culture with a range of cell types. Soft Matter, 6 (20). pp. 5080-5088. ISSN 1744-683X

Jin, R. and Moreira Teixeira, L.S. and Dijkstra, P.J. and Karperien, H.B.J. and Blitterswijk, C.A. van and Feijen, J. (2010) Enzymatically-crosslinked injectable hydrogels based on biomimetic dextran–hyaluronic acid conjugates for cartilage tissue engineering. Biomaterials, 31 (11). pp. 3103-3113. ISSN 0142-9612

Jin, R. and Moreira Teixeira, L.S. and Krouwels, A. and Dijkstra, P.J. and Blitterswijk, C.A. van and Karperien, M. and Feijen, J. (2010) Synthesis and characterization of hyaluronic acid–poly(ethylene glycol) hydrogels via Michael addition: An injectable biomaterial for cartilage repair. Acta Biomaterialia, 6 (6). pp. 1968-1977. ISSN 1742-7061

Jukes, Jojanneke M. and Aa, Leonardus J. van der and Hiemstra, Christine and Veen, Theun van and Dijkstra, Pieter J. and Zhong, Zhiyuan and Feijen, Jan and Blitterswijk, Clemens A. van and Boer, Jan de (2010) A Newly Developed Chemically Crosslinked Dextran–Poly(Ethylene Glycol) Hydrogel
for Cartilage Tissue Engineering.
Tissue Engineering. Part A, 16 (2). pp. 565-573. ISSN 1937-3341

Jukes, Jojanneke M. and Blitterswijk, Clemens A. van and Boer, Jan de (2010) Skeletal tissue engineering using embryonic stem cells. Journal of Tissue Engineering and Regenerative Medicine, 4 (3). pp. 165-180. ISSN 1932-6254

Liu, Jun and Barradas, Ana and Fernandes, Hugo and Janssen, Frank and Papenburg, Bernke and Stamatialis, Dimitrios and Martens, Anton and Blitterswijk, Clemens van and Boer, Jan de (2010) In Vitro and In Vivo Bioluminescent Imaging of Hypoxia in Tissue-Engineered Grafts. Tissue Engineering. Part C: methods, 16 (3). pp. 479-485. ISSN 1937-3384

Liu, Jun and Someren, Eugene and Mentink, Anouk and Licht, Ruud and Dechering, Koen and Blitterswijk, Clemens van and Boer, Jan de (2010) The effect of PKC activation and inhibition on osteogenic differentiation of human mesenchymal stem cells. Journal of Tissue Engineering and Regenerative Medicine, 4 (5). pp. 329-339. ISSN 1932-6254

Melchels, Ferry P.W. and Barradas, Ana M.C. and Blitterswijk, Clemens A. van and Boer, Jan de and Feijen, Jan and Grijpma, Dirk W. (2010) Effects of the architecture of tissue engineering scaffolds on cell seeding and culturing. Acta Biomaterialia, 6 (11). pp. 4208-4217. ISSN 1742-7061

Moroni, Lorenzo and Habibovic, Pamela and Mooney, David J. and Blitterswijk, Clemens A. van (2010) Functional Tissue Engineering Through Biofunctional Macromolecules and Surface Design. MRS Bulletin, 35 . pp. 584-590. ISSN 0883-7694

Nandakumar, Anandkumar and Fernandes, Hugo and Boer, Jan de and Moroni, Lorenzo and Habibovic, Pamela and Blitterswijk, Clemens A. van (2010) Fabrication of bioactive composite scaffolds by electrospinning for bone regeneration. Macromolecular Bioscience, 10 (11). pp. 1365-1373. ISSN 1616-5187

Nandakumar, Anandkumar and Yang, Liang and Habibovic, Pamela and Blitterswijk, Clemens van (2010) Calcium phosphate coated electrospun fiber matrices as scaffolds for bone tissue engineering. Langmuir, 26 (10). pp. 7380-7387. ISSN 0743-7463

Siddappa, Ramakrishnaiah and Doorn, Joyce and Liu, Jun and Langerwerf, Eli and Arends, Roel and Blitterswijk, Clemens van and Boer, Jan de (2010) Timing, rather than the concentration of cyclic AMP, correlates to osteogenic differentiation of human mesenchymal stem cells. Journal of Tissue Engineering and Regenerative Medicine, 4 (5). pp. 356-365. ISSN 1932-6254

Teixeira, S. and Fernandes, H. and Leusink, A. and Blitterswijk, C. van and Ferraz, M.P. and Monteiro, F.J. and Boer, J. de (2010) In vivo evaluation of highly macroporous ceramic scaffolds for bone tissue engineering. Journal of biomedical materials research. Part A, 93 (2). pp. 567-575. ISSN 1549-3296

Yang, Liang and Hedhammar, My and Blom, Tobias and Leifer, Klaus and Johansson, Jan and Habibovic, Pamela and Blitterswijk, Clemens A. van (2010) Biomimetic calcium phosphate coatings on recombinant spider silk fibres. Biomedical Materials, 5 (4). 045002. ISSN 1748-6041

Yang, Liang and Perez-Amodio, Soledad and Barrere-de Groot, Florence Y.F. and Everts, Vincent and Blitterswijk, Clemens A. van and Habibovic, Pamela (2010) The effects of inorganic additives to calcium phosphate on in vitro behavior of osteoblasts and osteoclasts. Biomaterials, 31 (11). pp. 2976-2989. ISSN 0142-9612

Yuan, Huipin and Fernandes, Hugo and Habibovic, Pamela and Boer, Jan de and Barradas, Ana M.C. and Ruiter, Ad de and Walsh, William R. and Blitterswijk, Clemens A. van and Bruijn, Joost D. de (2010) Osteoinductive ceramics as a synthetic alternative to autologous bone grafting. Proceedings of the National Academy of Sciences of the United States of America, PNAS, 107 (31). pp. 13614-13619. ISSN 0027-8424

2009

Fedorovich, Natalja E. and Swennen, Ives and Girones, Jordi and Moroni, Lorenzo and Blitterswijk, Clemens A. van and Schacht, Etienne and Alblas, Jacqueline and Dhert, Wouter J.A. (2009) Evaluation of Photocrosslinked Lutrol Hydrogel for Tissue Printing Applications. Biomacromolecules, 10 (7). pp. 1689-1696. ISSN 1525-7797

Fennema, Eelco M. and Renard, Auke J.S. and Leusink, Anouk and Blitterswijk, Clemens A. van and Boer, Jan de (2009) The effect of bone marrow aspiration strategy on the yield and quality of human mesenchymal stem cells. Acta orthopaedica, 80 (5). pp. 618-621. ISSN 1745-3674

Fernandes, Hugo and Dechering, Koen and Someren, Eugene van and Steeghs, Ilse and Apotheker, Marion and Leusink, Anouk and Bank, Ruud and Janeczek, Karolina and Blitterswijk, Clemens van and Boer, Jan de (2009) The Role of Collagen Crosslinking in Differentiation of Human Mesenchymal Stem Cells and MC3T3-E1 Cells. Tissue Engineering. Part A, 15 (12). pp. 3857-3867. ISSN 1937-3341

Fernandes, Hugo and Moroni, Lorenzo and Blitterswijk, Clemens van and Boer, Jan de (2009) Extracellular matrix and tissue engineering applications. Journal of Materials Chemistry, 19 (31). pp. 5474-5484. ISSN 0959-9428

Higuera, Gustavo and Schop, Deborah and Janssen, Frank and Dijkhuizen-Radersma, Riemke van and Boxtel, Ton van and Blitterswijk, Clemens A. van (2009) Quantifying In Vitro Growth and Metabolism Kinetics of Human Mesenchymal Stem Cells Using a Mathematical Model. Tissue Engineering. Part A, 15 (9). pp. 2653-2663. ISSN 1937-3341

Janssen, F.W. and Dijkhuizen-Radersma, R. van and Oorschot, A. van and Oostra, J. and Bruijn, J.D. de and Blitterswijk, C.A. van (2009) Human tissue-engineered bone produced in clinically relevant amounts using a semi-automated perfusion bioreactor system: a preliminary study. Journal of Tissue Engineering and Regenerative Medicine, 4 (1). pp. 12-24. ISSN 1932-6254

Jin, R. and Moreira Teixeira, L.S. and Dijkstra, P.J. and Karperien, M. and Blitterswijk, C.A. van and Zhong, Z.Y. and Feijen, J. (2009) Injectable chitosan-based hydrogels for cartilage tissue engineering. Biomaterials, 30 (13). pp. 2544-2551. ISSN 0142-9612

Kruyt, Moyo C. and Delawi, Diyar and Habibovic, Pamela and Oner, F. Cumhur and Blitterswijk, Clemens A. van and Dhert, Wouter J.A. (2009) Relevance of bone graft viability in a goat transverse process model. Journal of Orthopaedic Research, 27 (8). pp. 1055-1059. ISSN 0736-0266

Li, J.P. and Wijn, J.R. de and Blitterswijk, C.A. van and Groot, K. de (2009) The effect of scaffold architecture on properties of direct 3D fiber deposition of porous Ti6Al4V for orthopedic implants. Journal of biomedical materials research. Part A, 92 (1). pp. 33-42. ISSN 1549-3296

Papenburg, B.J. and Boer, J. de and Grijpma, D. and Feijen, J. and Blitterswijk, C.A. van and Wessling, M. and Stamatialis, D. (2009) Novel membrane-based scaffolds for tissue engineering. International journal of artificial organs, 32 (7). pp. 409-410. ISSN 0391-3988

Papenburg, Bernke J. and Liu, Jun and Higuera, Gustavo and Barradas, Ana M.C. and Boer, Jan de and Blitterswijk, Clemens A. van and Wessling, Matthias and Stamatialis, Dimitrios (2009) Development and analysis of multi-layer scaffolds for tissue engineering. Biomaterials, 30 (31). pp. 6228-6239. ISSN 0142-9612

Rivron, N.C. and Le Gac, S. and Vrij, E. and Rouwkema, J. and Wijnperle, D. and Truckenmuller, R. and Berg, A. van den and Blitterswijk, C.A. van (2009) Microfabrication of shaped MM-scale tissues to study vascular development using modular bottom-up approach. In: MicroTAS 2009, Thirteenth International Conference on Miniaturized Systems for Chemistry and Life Sciences, 1-5 Nov 2009, Jeju, Korea (pp. pp. 9-11).

Rivron, Nicolas C. and Rouwkema, Jeroen and Truckenmüller, Roman and Karperien, Marcel and Boer, Jan de and Blitterswijk, Clemens A. van (2009) Tissue assembly and organization: Developmental mechanisms in microfabricated tissues. Biomaterials, 30 (28). pp. 4851-4858. ISSN 0142-9612

Rouwkema, Jeroen and Westerweel, Peter E. and Boer, Jan de and Verhaar, Marianne C. and Blitterswijk, Clemens A. van (2009) The Use of Endothelial Progenitor Cells for Prevascularized Bone Tissue Engineering. Tissue Engineering. Part A, 15 (8). pp. 2015-2027. ISSN 1937-3341

Siddappa, Ramakrishnaiah and Mulder, Winfried and Steeghs, Ilse and Klundert, Christine van de and Fernandes, Hugo and Liu, Jun and Arends, Roel and Blitterswijk, Clemens van and Boer, Jan de (2009) cAMP/PKA Signaling Inhibits Osteogenic Differentiation and Bone Formation in Rodent Models. Tissue Engineering. Part A, 15 (8). pp. 2135-2143. ISSN 1937-3341

Sun, Lanying and Wu, Ling and Bao, Chongyun and Fu, Chunhua and Wang, Xinlong and Yao, Jinfeng and Zhang, Xingdong and Blitterswijk, Clemens A. van (2009) Gene expressions of Collagen type I, ALP and BMP-4 in osteo-inductive BCP implants show similar pattern to that of natural healing bones. Materials Science and Engineering C: Biomimetic materials, sensors and systems, 29 (6). pp. 1829-1834. ISSN 0928-4931

Wang, Jiawei and Groot, Klaas de and Blitterswijk, Clemens van and Boer, Jan de (2009) lectrolytic deposition of lithium into calcium phosphate coatings. Dental Materials, 25 (3). pp. 353-359. ISSN 0109-5641

Woodfield, T.B.F. and Guggenheim, M. and Rechenberg, B. von and Riesle, J. and Blitterswijk, C.A. van and Wedler, V. (2009) Rapid prototyping of anatomically shaped, tissue-engineered implants for restoring congruent articulating surfaces in small joints. Cell Proliferation, 42 (4). pp. 485-497. ISSN 0960-7722

2008

Barrère, F. and Mahmood, T.A. and Groot, K. de and Blitterswijk, C.A. van (2008) Advanced biomaterials for skeletal tissue regeneration: Instructive and smart functions. Materials Science and Engineering R: Reports, 59 (1-6). pp. 38-71. ISSN 0927-796X

Fernandes, Hugo and Dechering, Koen and Someren, Eugene van and Blitterswijk, Clemens van and Boer, Jan de (2008) Investigating the role of the extracellular matrix on differentiation of human mesenchymal stem cells and MC3T3 cells. Bone, 42 (Suppl. 1). S21. ISSN 8756-3282

Habibovic, Pamela and Gbureck, Uwe and Doillon, Charles J. and Bassett, David C. and Blitterswijk, Clemens A. van and Barralet, Jake E. (2008) Osteoconduction and osteoinduction of low-temperature 3D printed bioceramic implants. Biomaterials, 29 (7). pp. 944-953. ISSN 0142-9612

Habibovic, Pamela and Kruyt, Moyo C. and Juhl, Maria V. and Clyens, Stuart and Martinetti, Roberta and Dolcini, Laura and Theilgaard, Naseem and Blitterswijk, Clemens A. van (2008) Comparative in vivo study of six hydroxyapatite-based bone graft substitutes. Journal of Orthopaedic Research, 26 (10). pp. 1363-1370. ISSN 0736-0266

Jukes, Jojanneke M. and Both, Sanne Karijn and Leusink, Anouk and Sterk, Lotus M.Th. and Blitterswijk, Clemens A. van and Boer, Jan de (2008) Endochondral bone tissue engineering using embryonic stem cells. Proceedings of the National Academy of Sciences of the United States of America, PNAS, 105 (19). pp. 6840-6845. ISSN 0027-8424

Jukes, Jojanneke M. and Moroni, Lorenzo and Blitterswijk, Clemens A. van and Boer, Jan de (2008) Critical Steps toward a Tissue-Engineered Cartilage Implant Using Embryonic Stem Cells. Tissue Engineering. Part A, 14 (1). pp. 135-147. ISSN 1937-3341

Kruyt, Moyo C. and Bruijn, Joost de and Rouwkema, Jeroen and Blitterswijk, Clemens van and Oner, Cumhur and Verbout, Ab and Dhert, Wouter (2008) Analysis of the Dynamics of Bone Formation, Effect of Cell Seeding Density, and Potential of Allogeneic Cells in Cell-Based Bone Tissue Engineering in Goats. Tissue Engineering. Part A, 14 (6). pp. 1081-1088. ISSN 1937-3341

Le Gac, Séverine and Rivron, Nicolas and Wijnperle, Daniel and Blitterswijk, Clemens van and Berg, Albert van den (2008) Cellular microtissues spontaneously formed in a microfabricated device for angiongenesis. In: 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, 12-16 October 2008, San Diego, CA (pp. pp. 1165-1167).

Leeuwenburgh, Sander C.G. and Jansen, John A. and Malda, Jos and Dhert, Wouter A. and Rouwkema, Jeroen and Blitterswijk, Clemens A. van and Kirkpatrick, C.James and Williams, David F. (2008) Trends in biomaterials research: An analysis of the scientific programme of the World Biomaterials Congress 2008. Biomaterials, 29 (21). pp. 3047-3052. ISSN 0142-9612

Li, Xiaoming and Blitterswijk, Clemens A. van and Feng, Qingling and Cui, Fuzhai and Watari, Fumio (2008) The effect of calcium phosphate microstructure on bone-related cells in vitro. Biomaterials, 29 (23). pp. 3306-3316. ISSN 0142-9612

Liu, Jun and Blitterswijk, Clemens A. van and Boer, Jan de (2008) Different protein kinase C isozymes exert opposing effects on osteogenesis of human mesenchymal stem cells. Bone, 42 (Suppl. 1). S25. ISSN 8756-3282

Meijer, Gert J. and Bruijn, Joost D. de and Koole, Ron and Blitterswijk, Clemens A. van (2008) Cell based bone tissue engineering in jaw defects. Biomaterials, 29 (21). pp. 3053-3061. ISSN 0142-9612

Moreira Teixeira, L. and Jin, R. and Dijkstra, P.J. and Feijen, J. and Blitterswijk, C. van and Karperien, M. (2008) Chitosan-Based Hydrogels as Extracellular Matrix for Cartilage Tissue Engineering: In vitro Biological Evaluation. Tissue Engineering. Part A, 14 (5). p. 711. ISSN 1937-3341

Moroni, Lorenzo and Hamann, Doreen and Paoluzzi, Luca and Pieper, Jeroen and Wijn, Joost R. de and Blitterswijk, Clemens A. van (2008) Regenerating articular tissue by converging technologies. PLoS ONE, 3 (8). ISSN 1932-6203

Papenburg, Bernke and Schuller, Sigrid and Stamatialis, Dimitrios and Grijpma, Dirk and Boer, Jan de and Blitterswijk, Clemens van and Wessling, Matthias (2008) Flexible micropatterned porous scaffolds: poster presentation. Tissue Engineering. Part A, 14 (5). p. 855. ISSN 1937-3341

Rivron, N.C. and Liu, J. and Rouwkema, J. and Boer, J. de and Blitterswijk, C.A. van (2008) Engineering vascularised tissues in vitro. European Cells & Materials, 15 . pp. 27-40. ISSN 1473-2262

Rouwkema, Jeroen and Rivron, Nicolas C. and Blitterswijk, Clemens A. van (2008) Vascularization in tissue engineering. Trends in Biotechnology, 26 (8). pp. 434-441. ISSN 0167-7799

Siddappa, Ramakrishnaiah and Martens, Anton and Doorn, Joyce and Leusink, Anouk and Olivo, Cristina and Licht, Ruud and Rijn, Linda van and Gaspar, Claudia and Fodde, Riccardo and Janssen, Frank and Blitterswijk, Clemens van and Boer, Jan de (2008) cAMP/PKA pathway activation in human mesenchymal stem cells in vitro results in robust bone formation in vivo. Proceedings of the National Academy of Sciences of the United States of America, PNAS, 105 (20). pp. 7281-7286. ISSN 0027-8424

Truckenmüller, R. and Giselbrecht, S. and Blitterswijk, C. van and Dambrowsky, N. and Gottwald, E. and Mappes, T. and Rolletschek, A. and Saile, V. and Trautmann, C. and Weibezahn, K.-F. and Welle, A. (2008) Flexible fluidic microchips based on thermoformed and locally modified thin
polymer films.
Lab on a Chip, 8 (9). pp. 1570-1579. ISSN 1473-0197

Yuan, Huipin and Groot, Klaas de and Blitterswijk, Clemens A. van and Bruijn, Joost D. de (2008) Preparation of a Resorbable Osteoinductive Tricalcium Phosphate Ceramic. European Cells & Materials, 16 (Suppl. 2). p. 14. ISSN 1473-2262

2007

Both, Sanne K. and Muijsenberg, Adrie J.C. van der and Blitterswijk, Clemens A. van and Boer, Jan de and Bruijn, Joost D. de (2007) A Rapid and Efficient Method for Expansion of Human Mesenchymal Stem Cells. Tissue Engineering, 13 (1). pp. 3-9. ISSN 1076-3279

Habibovic, Pamela and Woodfield, Tim and Groot, Klaas de and Blitterswijk, Clemens van (2007) Predictive Value of In Vitro and In Vivo Assays in Bone and Cartilage Repair -What do They Really Tell Us about the Clinical Performance? In: Tissue Engineering. Springer, New York, pp. 327-360. ISBN 9780387326641

Hendriks, Jeanine and Riesle, Jens and Blitterswijk, Clemens A. van (2007) Co-culture in cartilage tissue engineering. Journal of Tissue Engineering and Regenerative Medicine, 1 (3). pp. 170-178. ISSN 1932-6254

Kruyt, Moyo C. and Dhert, Wouter J.A. and Oner, F. Cumhur and Blitterswijk, Clemens A. van and Verbout, Abraham J. and Bruijn, Joost D. de (2007) Analysis of ectopic and orthotopic bone formation in cell-based tissue-engineered constructs in goats. Biomaterials, 28 (10). pp. 1798-1805. ISSN 0142-9612

Li, Jia Ping and Habibovic, Pamela and Doel, Mirella van den and Wilson, Clayton E. and Wijn, Joost R. de and Blitterswijk, Clemens A. van and Groot, Klaas de (2007) Bone ingrowth in porous titanium implants produced by 3D fiber deposition. Biomaterials, 28 (18). pp. 2810-2820. ISSN 0142-9612

Li, JiaPing and Habibovic, Pamela and Yuan, Huipin and Doel, Mirella van den and Wilson, Clayton E. and Wijn, Joost R. de and Blitterswijk, Clemens A. van and Groot, Klaas de (2007) Biological performance in goats of a porous titanium alloy–biphasic calcium phosphate composite. Biomaterials, 28 (29). pp. 4209-4218. ISSN 0142-9612

Liu, Jun and Blitterswijk, Clemens van and Martens, Anton and Boer, Jan de (2007) Non-invasive imaging of hypoxia in tissue engineering. European Cells & Materials, 14 (Suppl. 1). p. 8. ISSN 1473-2262

Manen, Henk-Jan van and Apeldoorn, Aart A. van and Verrijk, Ruud and Blitterswijk, Clemens A. van and Otto, Cees (2007) Intracellular degradation of microspheres based on cross-linked dextran hydrogels or amphiphilic block copolymers: A comparative Raman microscopy study. International Journal of Nanomedicine, 2 (2). pp. 241-252. ISSN 1176-9114

Moroni, L. and Hendriks, J.A.A. and Schotel, R. and Wijn, J.R. de and Blitterswijk, C.A. van (2007) Design of Biphasic Polymeric 3-Dimensional Fiber Deposited Scaffolds for Cartilage Tissue Engineering Applications. Tissue Engineering, 13 (2). pp. 361-371. ISSN 1076-3279

Siddappa, Ramakrishnaiah and Fernandes, Hugo and Liu, Jun and Blitterswijk, Clemens van and Boer, Jan de (2007) The Response of Human Mesenchymal Stem Cells to Osteogenic Signals and its Impact on Bone Tissue Engineering. Current stem cell research & therapy, 2 (3). pp. 209-220. ISSN 1574-888X

Siddappa, Ramakrishnaiah and Licht, Ruud and Blitterswijk, Clemens van and Boer, Jan de (2007) Donor variation and loss of multipotency during in vitro expansion of human mesenchymal stem cells for bone tissue engineering. Journal of Orthopaedic Research, 25 (8). pp. 1029-1041. ISSN 0736-0266

Siddappa, Ramakrishnaiah and Licht, Ruud and Liu, Jun and Blitterswijk, Clemens van and Boer, Jan de (2007) Controlling osteogenesis by/of human mesenchymal cells. European Cells & Materials, 14 (Suppl. 1). p. 36. ISSN 1473-2262

Sohier, J. and Hamann, D. and Koenders, M. and Cucchiarini, M. and Madry, H. and Blitterswijk, C. van and Groot, K. de and Bezemer, J.M. (2007) Tailored release of TGF-β1 from porous scaffolds for cartilage tissue engineering. International Journal of Pharmaceutics, 332 (1-2). pp. 80-89. ISSN 0378-5173

2006

Boer, Jan de and Blitterswijk, Clemens van and Löwik, Clemens (2006) Bioluminescent imaging: Emerging technology for non-invasive imaging of bone tissue engineering. Biomaterials, 27 (9). pp. 1851-1858. ISSN 0142-9612

Boer, Jan de and Licht, Ruud and Bongers, Marloes and Klundert, Tessa van der and Arends, Roel and Blitterswijk, Clemens van (2006) Inhibition of Histone Acetylation as a Tool in Bone Tissue Engineering. Tissue Engineering, 12 (10). 2927 -2937. ISSN 1076-3279

Habibovic, Pamela and Li, JiaPing and Valk, Chantal M. van der and Meijer, Gert and Layrolle, Pierre and Blitterswijk, Clemens A. van and Groot, Klaas de (2006) Biological performance of uncoated and octacalcium phosphate-coated Ti6Al4V. Biomaterials, 26 (1). pp. 23-36. ISSN 0142-9612

Habibovic, Pamela and Sees, Tara M. and Doel, Mirella van den and Blitterswijk, Clemens A. van and Groot, Klaas de (2006) Osteoinduction by biomaterials - Physicochemical and structural influences. Journal of Biomedical Materials Research. Part A, 77 (4). pp. 747-762. ISSN 1549-3296

Habibovic, Pamela and Yuan, Huipin and Doel, Mirella van den and Sees, Tara M. and Blitterswijk, Clemens A. van and Groot, Klaas de (2006) Relevance of Osteoinductive Biomaterials in Critical-Sized Orthotopic Defect. Journal of Orthopaedic Research, 24 (5). pp. 867-876. ISSN 0736-0266

Hendriks, Jeanine and Riesle, Jens and Blitterswijk, Clemens A. van (2006) Effect of Stratified Culture Compared to Confluent Culture in Monolayer on Proliferation and Differentiation of Human Articular Chondrocytes. Tissue Engineering, 120 (9). pp. 2397-2405. ISSN 1076-3279

Janssen, F.W. and Hofland, I. and Oorschot, A. van and Oostra, J. and Peters, H. and Blitterswijk, C.A. van (2006) Online measurement of oxygen consumption by goat bone marrow stromal cells in a combined cell-seeding and proliferation perfusion bioreactor. Journal of Biomedical Materials Research. Part A, 79 (2). pp. 338-348. ISSN 1549-3296

Janssen, Frank W. and Oostra, Jaap and Oorschot, Arie van and Blitterswijk, Clemens A. van (2006) A perfusion bioreactor system capable of producing clinically relevant volumes of tissue-engineered bone: In vivo bone formation showing proof of concept. Biomaterials, 27 (3). pp. 315-323. ISSN 0142-9612

Kruyt, Moyo C. and Wilson, Clayton E. and Bruijn, Joost D. de and Blitterswijk, Clemens A. van and Oner, Cumhur F. and Verbout, Abraham J. and Dhert, Wouter J.A. (2006) The effect of cell-based bone tissue engineering in a goat transverse process model. Biomaterials, 27 (29). pp. 5099-5106. ISSN 0142-9612

Li, Jia Ping and Wijn, Joost R. de and Blitterswijk, Clemens A. van and Groot, Klaas de (2006) Porous Ti6Al4V scaffold directly fabricating by rapid prototyping: preparation and in vitro experiment. Biomaterials, 27 (8). pp. 1223-1235. ISSN 0142-9612

Mahmood, Tahir A. and Miot, Sylvie and Frank, Oliver and Martin, Ivan and Riesle, Jens and Langer, Robert and Blitterswijk, Clemens A. van (2006) Modulation of Chondrocyte Phenotype for Tissue Engineering by Designing the Biological-Polymer Carrier Interface. Biomacromolecules, 7 (11). pp. 3012-3018. ISSN 1525-7797

Mahmood, Tahir A. and Shastri, V. Prasad and Blitterswijk, Clemens A. van and Langer, Robert and Riesle, Jens (2006) Evaluation of chondrogenesis within PEGT: PBT scaffolds with high PEG content. Journal of Biomedical Materials Research, 79A (1). pp. 216-222. ISSN 0021-9304

Moroni, L. and Poort, G. and Keulen, F. van and Wijn, J.R. de and Blitterswijk, C.A. van (2006) Dynamic mechanical properties of 3D fiber-deposited PEOT/PBT scaffolds: An experimental and numerical analysis. Journal of Biomedical Materials Research. Part A, 78 (3). pp. 605-614. ISSN 1549-3296

Moroni, L. and Wijn, J.R. de and Blitterswijk, C.A. van (2006) 3D fiber-deposited scaffolds for tissue engineering: Influence of pores geometry and architecture on dynamic mechanical properties. Biomaterials, 27 (7). pp. 974-985. ISSN 0142-9612

Moroni, Lorenzo and Licht, Ruud and Boer, Jan de and Wijn, Joost R. de and Blitterswijk, Clemens A. van (2006) Fiber diameter and texture of electrospun PEOT/PBT scaffolds influence human mesenchymal stem cell proliferation and morphology, and the release of incorporated compounds. Biomaterials, 27 (28). pp. 4911-4922. ISSN 0142-9612

Moroni, Lorenzo and Schotel, Roka and Sohier, Jerome and Wijn, Joost R. de and Blitterswijk, Clemens A. van (2006) Polymer hollow fiber three-dimensional matrices with controllable cavity and shell thickness. Biomaterials, 27 (35). pp. 5918-5928. ISSN 0142-9612

Rouwkema, Jeroen and Boer, Jan de and Blitterswijk, Clemens A. van (2006) Endothelial Cells Assemble into a 3-Dimensional Prevascular Network in a Bone Tissue Engineering Construct. Tissue Engineering, 12 (9). pp. 2685-2693. ISSN 1076-3279

Sohier, J. and Vlugt, T.J.H. and Cabrol, N. and Blitterswijk, C. van and Groot, K. de and Bezemer, J.M. (2006) Dual release of proteins from porous polymeric scaffolds. Journal of Controlled Release, 111 (1-2). pp. 95-106. ISSN 0168-3659

Wilson, Clayton E. and Kruyt, Moyo C. and Bruijn, Joost D. de and Blitterswijk, Clemens A. van and Oner, F. Cumhur and Verbout, Abraham J. and Dhert, Wouter J.A. (2006) A new in vivo screening model for posterior spinal bone formation: Comparison of ten calcium phosphate ceramic material treatments. Biomaterials, 27 (3). pp. 302-314. ISSN 0142-9612

Woodfield, Tim B.F. and Miot, Sylvie and Martin, Ivan and Blitterswijk, Clemens A. van and Riesle, Jens (2006) The regulation of expanded human nasal chondrocyte re-differentiation capacity by substrate composition and gas plasma surface modification. Biomaterials, 27 (7). pp. 1043-1053. ISSN 0142-9612

Yuan, H. and Blitterswijk, C.A. van and Groot, K. de and Bruijn, J.D. de (2006) A comparison of bone formation in biphasic calcium phosphate (BCP) and hydroxyapatite (HA) implanted in muscle and bone of dogs at different time periods. Journal of Biomedical Materials Research. Part A, 78 (1). pp. 139-147. ISSN 1549-3296

Yuan, Huipin and Blitterswijk, Clemens A. van and Groot, Klaas de and Bruijn, Joost D. de (2006) Cross-species Comparison of Ectopic Bone Formation in Biphasic Calcium Phosphate (BCP) and Hydroxyapatite (HA) Scaffolds. Tissue Engineering, 12 (6). pp. 1607-1615. ISSN 1076-3279

2005

Apeldoorn, A.A. van and Aksenov, Y. and Stigter, M. and Hofland, I. and Bruijn, J.D. de and Koerten, H.K. and Otto, C. and Greve, J. and Blitterswijk, C.A. van (2005) Parallel high-resolution confocal Raman SEM analysis of inorganic and organic bone matrix constituents. Journal of the Royal Society Interface, 2 (2). pp. 39-45. ISSN 1742-5689

Dekker, Robert J. and Bruijn, Joost D. de and Stigter, Martin and Barrere, Florence and Layrolle, Pierre and Blitterswijk, Clemens A. van (2005) Bone tissue engineering on amorphous carbonated apatite and crystalline octacalcium phosphate-coated titanium discs. Biomaterials, 26 (25). pp. 5231-5239. ISSN 0142-9612

Habibovic, Pamela and Yuan, Huipin and Valk, Chantal M. van der and Meijer, Gert and Blitterswijk, Clemens A. van and Groot, Klaas de (2005) 3D microenvironment as essential element for osteoinduction by biomaterials. Biomaterials, 26 (17). pp. 3565-3575. ISSN 0142-9612

Levenberg, Shulamit and Rouwkema, Jeroen and Macdonald, Mara and Garfein, Evan S. and Kohane, Daniel S. and Darland, Diane C. and Marini, Robert and Blitterswijk, Clemens A. van and Mulligan, Richard C. and D'Amore, Patricia A. and Langer, Robert (2005) Engineering vascularized skeletal muscle tissue. Nature biotechnology, 23 (7). pp. 879-884. ISSN 1087-0156

Li, J.P. and Li, S.H. and Blitterswijk, C.A. van and Groot, K. de (2005) A novel porous Ti6Al4V: Characterization and cell attachment. Journal of Biomedical Materials Research. Part A, 73 (2). pp. 223-233. ISSN 1549-3296

Mahmood, Tahir A. and Shastri, V. Prasad and Blitterswijk, Clemens A. van and Langer, Robert and Riesle, Jens (2005) Tissue Engineering of Bovine Articular Cartilage within Porous Poly(ether ester) Copolymer Scaffolds with Different Structures. Tissue Engineering, 112 (7-8). pp. 1244-1253. ISSN 1076-3279

Malda, J. and Woodfield, T.B.F. and Vloodt, F. van der and Wilson, C. and Martens, D.E. and Tramper, J. and Blitterswijk, C.A. van and Riesle, J. (2005) The effect of PEGT/PBT scaffold architecture on the composition of tissue engineered cartilage. Biomaterials, 26 (1). pp. 63-72. ISSN 0142-9612

Miot, Sylvie and Woodfield, Tim and Daniels, Alma U. and Suetterlin, Rosemarie and Peterschmitt, Iman and Heberer, Michael and Blitterswijk, Clemens A. van and Riesle, Jens and Martin, Ivan (2005) Effects of scaffold composition and architecture on human nasal chondrocyte redifferentiation and cartilaginous matrix deposition. Biomaterials, 26 (15). pp. 2479-2489. ISSN 0142-9612

Moroni, L. and Wijn, J.R. de and Blitterswijk, C.A. van (2005) Three-dimensional fiber-deposited PEOT/PBT copolymer scaffolds for tissue engineering: Influence of porosity, molecular network mesh size, and swelling in aqueous media on dynamic mechanical properties. Journal of Biomedical Materials Research. Part A, 75 (4). pp. 957-965. ISSN 1549-3296

Wang, Hongjun and Pieper, Jeroen and Peters, Fabienne and Blitterswijk, Clemens A. van and Lamme, Evert N. (2005) Synthetic scaffold morphology controls human dermal connective tissue formation. Journal of Biomedical Materials Research. Part A, 74 (4). pp. 523-532. ISSN 1549-3296

Woodfield, T.B.F. and Blitterswijk, C.A. van and Wijn, J. de and Sims, T.J. and Hollander, A.P. and Riesle, J. (2005) Polymer Scaffolds Fabricated with Pore-Size Gradients as a Model for Studying the Zonal Organization within Tissue-Engineered Cartilage Constructs. Tissue Engineering, 11 (9-10). pp. 1297-1311. ISSN 1076-3279

2004

Apeldoorn, Aart A. van and Manen, Henk-Jan van and Bezemer, Jeroen M. and Bruijn, Joost D. de and Blitterswijk, Clemens A. van and Otto, Cees (2004) Raman Imaging of PLGA Microsphere Degradation Inside Macrophages. Journal of the American Chemical Society, 126 . pp. 13226-13227. ISSN 0002-7863

Barrere, Florence and Snel, Margot M.E. and Blitterswijk, Clemens A. van and Groot, Klaas de and Layrolle, Pierre (2004) Nano-scale study of the nucleation and growth of calcium phosphate coating on titanium implants. Biomaterials, 25 (14). pp. 2901-2910. ISSN 0142-9612

Boer, Jan de and Siddappa, Ramakrishnaiah and Gaspar, Claudia and Apeldoorn, Aart van and Fodde, Riccardo and Blitterswijk, Clemens van (2004) Wnt signaling inhibits osteogenic differentiation of human mesenchymal stem cells. Bone, 34 (5). pp. 818-826. ISSN 8756-3282

Boer, Jan de and Wang, Hong Jun and Blitterswijk, Clemens van (2004) Effects of Wnt Signaling on Proliferation and Differentiation of Human Mesenchymal Stem Cells. Tissue Engineering, 10 (3-4). pp. 393-401. ISSN 1076-3279

Dijkhuizen-Radersma, R. van and Roosma, J.R. and Sohier, J. and Peters, F.L.A.M.A. and Doel, M. van den and Blitterswijk, C.A. van and Groot, K. de and Bezemer, J.M. (2004) Biodegradable poly(ether-ester) multiblock copolymers for controlled release applications: an in vivo evaluation. Journal of Biomedical Materials Research. Part A, 71A (1). pp. 118-127. ISSN 1549-3296

Habibovic, P. and Valk, C.M. van der and Blitterswijk, C.A. van and Groot, K. de (2004) Influence of octacalcium phosphate coating on osteoinductive properties of biomaterials. Journal of Materials Science: Materials in Medicin, 15 (4). pp. 373-380. ISSN 0957-4530

Kruyt, Moyo C. and Dhert, Wouter J.A. and Oner, Cumhur and Blitterswijk, Clemens A. van and Verbout, Abraham J. and Bruijn, Joost D. de (2004) Optimization of bone-tissue engineering in goats. Journal of Biomedical Materials Research. Part B: Applied biomaterials, 69 (2). pp. 113-120. ISSN 0021-9304

Kruyt, Moyo C. and Dhert, Wouter J.A. and Yuan, Huipin and Wilson, Clayton E. and Blitterswijk, Clemens A. van and Verbout, Abraham J. and Bruijn, Joost D. de (2004) Optimization of bone-tissue engineering in goats. Journal of Orthopaedic Research, 22 (3). pp. 544-551. ISSN 0736-0266

Kruyt, Moyo C. and Dhert, Wouter J.A. and Yuan, Huipin and Wilson, Clayton E. and Blitterswijk, Clemens A. van and Verbout, Abraham J. and Bruijn, Joost D. de (2004) Bone tissue engineering in a critical size defect compared to ectopic implantations in the goat. Journal of Orthopaedic Research, 22 (3). pp. 544-551. ISSN 0736-0266

Mahmood, Tahir A. and Jong, Ruben de and Riesle, Jens and Langer, Robert and Blitterswijk, Clemens A. van (2004) Adhesion-mediated signal transduction in human articular chondrocytes: the influence of biomaterial chemistry and tenascin-C. Experimental Cell Research, 301 (2). pp. 179-188. ISSN 0014-4827

Malda, J. and Rouwkema, J. and Martens, D.E. and Comte, E.P. le and Kooy, F.K. and Tramper, J. and Blitterswijk, C.A. van and Riesle, J. (2004) Oxygen gradients in tissue-engineered Pegt/Pbt cartilaginous constructs: Measurement and modeling. Biotechnology and Bioengineering, 86 (1). pp. 9-18. ISSN 0006-3592

Malda, J. and Blitterswijk, C.A. van and Geffen, M. van and Martens, D.E. and Tramper, J. and Riesle, J. (2004) Low oxygen tension stimulates the redifferentiation of dedifferentiated adult human nasal chondrocytes. Osteoarthritis and Cartilage, 12 (4). pp. 306-313. ISSN 1063-4584

Malda, J. and Woodfield, T.B.F. and Vloodt, F. van der and Kooy, F.K. and Martens, D.E. and Tramper, J.C. and Blitterswijk, C.A. van and Riesle, J. (2004) The effect of PEGT/PBT scaffold architecture on oxygen gradients in tissue engineered cartilaginous constructs. Biomaterials, 25 (26). pp. 5773-5780. ISSN 0142-9612

Wang, Hong-Jun and Pieper, Jeroen and Schotel, Roka and Blitterswijk, Clemens A. van and Lamme, Evert N. (2004) Stimulation of Skin Repair Is Dependent on Fibroblast Source and Presence of Extracellular Matrix. Tissue Engineering, 10 (7-8). pp. 1054-1064. ISSN 1076-3279

Wilson, C.E. and Bruijn, J.D. de and Blitterswijk, C.A. van and Verbout, A.J. and Dhert, W.J.A. (2004) Design and fabrication of standardized hydroxyapatite scaffolds with a defined macro-architecture by rapid prototyping for bone-tissue-engineering research. Journal of Biomedical Materials Research. Part A, 68 (1). pp. 123-132. ISSN 1549-3296

Woodfield, T.B.F. and Malda, J. and Wijn, J. de and Peters, F. and Riesle, J. and Blitterswijk, C.A. van (2004) Design of porous scaffolds for cartilage tissue engineering using a three-dimensional fiber-deposition technique. Biomaterials, 25 (18). pp. 4149-4161. ISSN 0142-9612

2003

Barrere, F. and Valk, C.M. van der and Dalmeijer, R.A.J. and Blitterswijk, C.A. van and Groot, K. de and Layrolle, P. (2003) In vitro and in vivo degradation of biomimetic octacalcium phosphate and carbonate apatite coatings on titanium implants. Journal of Biomedical Materials Research. Part A, 64 (2). pp. 378-387. ISSN 1549-3296

Barrere, Florence and Valk, Chantal M. van der and Dalmeijer, Remco A.J. and Meijer, Gert and Blitterswijk, Clemens A. van and Groot, Klaas de and Layrolle, Pierre (2003) Osteogenecity of octacalcium phosphate coatings applied on porous metal implants. Journal of Biomedical Materials Research. Part A, 66 (4). pp. 779-788. ISSN 1549-3296

Liu, Y. and Hunziker, E.B. and Layrolle, P. and Blitterswijk, C.A. van and Calvert, P.D. and Groot, K. de (2003) Remineralization of demineralized albumin-calcium phosphate coatings. Journal of Biomedical Materials Research. Part A, 67 (4). pp. 1155-1162. ISSN 1549-3296

Malda, J. and Blitterswijk, C.A. van and Grojec, M. and Martens, D.E. and Tramper, J. and Riesle, J. (2003) Expansion of Bovine Chondrocytes on Microcarriers Enhances Redifferentiation. Tissue Engineering, 9 (5). pp. 939-948. ISSN 1076-3279

Malda, J. and Kreijveld, E. and Temenoff, J.S. and Blitterswijk, C.A. van and Riesle, J. (2003) Expansion of human nasal chondrocytes on macroporous microcarriers enhances redifferentiation. Biomaterials, 24 (28). pp. 5153-5161. ISSN 0142-9612

Mendes, S.C. and Bezemer, J. and Claase, M.B. and Grijpma, D.W. and Bellia, G. and Degli-Innocenti, F. and Reis, R.L. and Groot, K. de and Blitterswijk, C.A. van and Bruijn, J.D. de (2003) Evaluation of Two Biodegradable Polymeric Systems as Substrates for Bone Tissue Engineering. Tissue Engineering, 9 (Suppl.). pp. 91-101. ISSN 1076-3279

Wang, Hong-Jun and Bertrand-de Haas, Marion and Blitterswijk, Clemens A. van and Lamme, Evert N. (2003) Engineering of a Dermal Equivalent: Seeding and Culturing Fibroblasts in PEGT/PBT Copolymer Scaffolds. Tissue Engineering, 9 (5). pp. 909-917. ISSN 1076-3279

2002

Aksenov, Y. and Apeldoorn, A.A. van and Bruijn, J.C. de and Blitterswijk, C.A. van and Greve, J. and Otto, C. (2002) Combined confocal Raman microscope with scanning electron microscope; a parallel analysis of inorganic materials. Microscopy and Analysis, 8 (Suppl. S02). pp. 1386-1387. ISSN 0958-1952

Barrere, F. and Blitterswijk, C.A. van and Groot, K. de and Layrolle, P. (2002) Nucleation of biomimetic Ca–P coatings on Ti6Al4V from a SBF×5 solution: influence of magnesium. Biomaterials, 23 (10). pp. 2211-2220. ISSN 0142-9612

Barrere, F. and Blitterswijk, C.A. van and Groot, K. de and Layrolle, P. (2002) Influence of ionic strength and carbonate on the Ca-P coating formation from SBF×5 solution. Biomaterials, 23 (9). pp. 1921-1930. ISSN 0142-9612

El-Ghalbzouri, A. and Gibbs, S. and Lamme, E. and Blitterswijk, C.A. van and Ponec, M. (2002) Effect of fibroblasts on epidermal regeneration. British Journal of Dermatology, 147 (2). pp. 230-243. ISSN 0007-0963

Habibovic, Pamela and Barrere, Florence and Blitterswijk, Clemens A. van and Groot, Klaas de and Layrolle, Pierre (2002) Biomimetic Hydroxyapatite Coating on Metal Implants. Journal of the American Ceramic Society, 85 (3). pp. 517-522. ISSN 0002-7820

Mendes, S.C. and Tibbe, J.M. and Veenhof, M. and Bakker, K. and Both, S. and Platenburg, P.P. and Oner, F.C. and Bruijn, J.D. de and Blitterswijk, C.A. van (2002) Bone Tissue-Engineered Implants Using Human Bone Marrow Stromal Cells: Effect of Culture Conditions and Donor Age. Tissue Engineering, 8 (6). pp. 911-920. ISSN 1076-3279

2001

Liu, Yuelian and Layrolle, Pierre and Bruijn, Joost de and Blitterswijk, Clemens van and Groot, Klaas de (2001) Biomimetic coprecipitation of calcium phosphate and bovine serum albumin on titanium alloy. Journal of Biomedical Materials Research. Part A, 57 (3). pp. 327-335. ISSN 1549-3296

Mendes, Sandra C. and Reis, R.L. and Bovell, Yvonne P. and Cunha, A.M. and Blitterswijk, Clemens A. van and Bruijn, Joost D. de (2001) Biocompatibility testing of novel starch-based materials with potential application in orthopaedic surgery: a preliminary study. Biomaterials, 22 (14). pp. 2057-2067. ISSN 0142-9612

Papadaki, Maria and Mahmood, Tahir and Gupta, Pavan and Claase, Menno B. and Grijpma, Dirk W. and Riesle, Jens and Blitterswijk, Clemens A. van and Langer, Robert (2001) The different behaviors of skeletal muscle cells and chondrocytes on PEGT/PBT block copolymers are related to the surface properties of the substrate. Journal of Biomedical Materials Research, 54 (1). pp. 47-58. ISSN 0021-9304

2000

Bezemer, J.M. and Grijpma, D.W. and Dijkstra, P.J. and Blitterswijk, C.A. van and Feijen, J. (2000) Control of protein delivery from amphiphilic poly(ether ester) multiblock copolymers by varying their water content using emulsification techniques. Journal of Controlled Release, 66 (2-3). pp. 307-320. ISSN 0168-3659

Bezemer, J.M. and Oude Weme, P. and Grijpma, D.W. and Dijkstra, P.J. and Blitterswijk, C.A. van and Feijen, J. (2000) Amphiphilic poly(ether ester amide) multiblock copolymers as biodegradable matrices for the controlled release of proteins. Journal of Biomedical Materials Research, 52 (1). pp. 8-17. ISSN 1549-3296

Bezemer, J.M. and Radersma, R. and Grijpma, D.W. and Dijkstra, P.J. and Feijen, J. and Blitterswijk, C.A. van (2000) Zero-order release of lysozyme from poly(ethylene glycol)/poly(butylene terephthalate) matrices. Journal of Controlled Release, 64 (1-3). pp. 179-192. ISSN 0168-3659

Bezemer, J.M. and Radersma, R. van and Grijpma, D.W. and Dijkstra, P.J. and Blitterswijk, C.A. van and Feijen, J. (2000) Microspheres for protein delivery prepared from amphiphilic multiblock copolymers: 1. Influence of preparation techniques on particle characteristics and protein delivery. Journal of Controlled Release, 67 (2-3). pp. 233-248. ISSN 0168-3659

Bezemer, J.M. and Radersma, R. van and Grijpma, D.W. and Dijkstra, P.J. and Blitterswijk, C.A. van and Feijen, J. (2000) Microspheres for protein delivery prepared from amphiphilic multiblock copolymers: 2. Modulation of release rate. Journal of Controlled Release, 67 (2-3). pp. 249-260. ISSN 0168-3659

1999

Barrere, F. and Layrolle, P. and Blitterswijk, C.A. van and Groot, K. de (1999) Biomimetic calcium phosphate coatings on Ti6Al4V: a crystal growth study of octacalcium phosphate and inhibition by Mg2+ and HCO3−. Bone, 25 (2, Sup). pp. 107-111. ISSN 8756-3282

Bezemer, J.M. and Grijpma, D.W. and Dijkstra, P.J. and Blitterswijk, C.A. van and Feijen, J. (1999) A controlled release system for proteins based on poly(ether ester) block-copolymers: polymer network characterization. Journal of Controlled Release, 62 (3). pp. 393-405. ISSN 0168-3659

1998

Liu, Q. and Wijn, J.R. de and Blitterswijk, C.A. van (1998) A study on the grafting reaction of isocyanates with hydroxyapatite particles. Journal of Biomedical Materials Research, 40 (3). pp. 358-364. ISSN 1549-3296

Liu, Q. and Wijn, J.R. de and Blitterswijk, C.A. van (1998) Covalent bonding of PMMA, PBMA, and poly(HEMA) to hydroxyapatite particles. Journal of Biomedical Materials Research, 40 (2-3). pp. 257-263. ISSN 1549-3296

Liu, Qing and Wijn, Joost R. de and Blitterswijk, Clemens A. van (1998) Composite biomaterials with chemical bonding between hydroxyapatite filler particles and PEG/PBT copolymer matrix. Journal of Biomedical Materials Research, 40 (3). pp. 490-497. ISSN 1549-3296

Liu, Qing and Wijn, Joost R. de and Groot, Klaas de and Blitterswijk, Clemens A. van (1998) Surface modification of nano-apatite by grafting organic polymer. Biomaterials, 19 (11-12). pp. 1067-1072. ISSN 0142-9612

1997

Blitterswijk, C.A. van (1997) Homo senescens : levensverlenging zonder kwaliteit? [Lecture]

Liu, Qing and Wijn, J.R. de and Blitterswijk, C.A. van (1997) Nano-apatite/polymer composites: mechanical and physicochemical characteristics. Biomaterials, 18 (19). pp. 1263-1270. ISSN 0142-9612

Meijer, G.J. and Heethaar, J. and Cune, M.S. and Putter, C. de and Blitterswijk, C.A. van (1997) Flexible (Polyactive®) versus rigid (hydroxyapatite) dental implants. International Journal of Oral and Maxillofacial Surgery, 26 (2). pp. 135-140. ISSN 0901-5027

1996

Meijer, G.J. and Dooren, A. van and Gallard, M.L. and Dalmeijer, R. and Putter, C. de and Koole, R. and Blitterswijk, C.A. van (1996) Polyactive as a bone-filler in a beagle dog model. International Journal of Oral and Maxillofacial Surgery, 25 (3). pp. 210-216. ISSN 0901-5027

This list was generated on Wed Nov 26 05:13:41 2014 CET.