Author Publications

1997

Maliepaard, Marc and Mol de, Nico J. and Tomasz, Maria and Gargiulo, Dario and Janssen, Lambert H.M. and Duynhoven van, John P.M. and Velzen van, Ewoud J.J. and Verboom, Willem and Reinhoudt, David N. (1997) Mitosene-DNA adducts. Characterization of two major DNA monoadducts formed by 1,10-bis(acetoxy)-7-methoxymitosene upon reductive activation. Biochemistry, 36 (30). pp. 9211-9220. ISSN 0006-2960

1996

Maliepaard, M. and Groot, S.E. and Mol de, N.J. and Janssen, L.H.M. and Freriks, M. and Verboom, W. and Reinhoudt, D.N. and Stratford, I.J. (1996) Chirality of a 1,10-bisacetoxymitosene compound. Impact on reductive activation, DNA interstrand cross-linking and antitumour activity. Anti-Cancer Drug Design, 11 . pp. 403-413. ISSN 0266-9536

1995

Maliepaard, Marc and Mol de, Nico J. and Janssen, Lambert H.M. and Goeptar, Arnold R. and Koppele te, Johan and Vermeulen, Nico P.E. and Verboom, Willem and Reinhoudt, David N. (1995) Reduction of antitumour mitosenes in non-aqueous and aqueous environment. An electron spin resonance and cyclic voltammetry study. Free Radical Research, 22 (2). pp. 109-121. ISSN 1071-5762

1994

Maliepaard, Marc and Sitters, Karin A.M.C. and Mol de, Nico J. and Janssen, Lambert H.M. and Stratford, Ian J. and Stephens, Miriam and Verboom, Willem and Reinhoudt, David N. (1994) Potential antitumour mitosenes: relationship between in vitro DNA interstrand cross-link formation and DNA damage in escherichia coli K-12 strains. Biochemical Pharmacology, 48 (7). pp. 9320-9323. ISSN 0006-2952

1993

Maliepaard, Marc and Mol de, Nico J. and Janssen, Lambert H.M. and Hoogvliet, Joop C. and Neut van der, Wouter and Verboom, Willem and Reinhoudt, David N. (1993) Reductive activation of potential antitumor mitosene compounds. Journal of Medical Chemistry, 1993 (36). pp. 2091-2097. ISSN 0022-2623

1992

Lusthof, Klaas J. and Mol de, Nicolaas J. and Richter, Wilma and Janssen, Lambert H.M. and Butler, John and Hoey, Brigid M. and Verboom, Willem and Reinhoudt, David N. (1992) Redox cycling of potential antitumor aziridinylquinones. Free Radical Biology & Medicine, 13 (6). pp. 599-608. ISSN 0891-5849

Maliepaard, M. and Mol de, N.J. and Janssen, L.H.M. and Neut van der, W. and Verboom, W. and Reinhoudt, D.N. (1992) Role of lipophilicity in the in vitro antitumour activity of a series of new mitosene compounds. Anti-Cancer Drug Design, 7 . pp. 415-425. ISSN 0266-9536

1990

Lusthof, K.J. and Richter, W. and Mol de, N.J. and Janssen, L.H.M. and Verboom, W. and Reinhoudt, D.N. (1990) Reductive activation of potential antitumor bis(aziridinyl)benzoquinones by xanthine oxidase: Competition between oxygen reduction and quinone reduction. Archives of Biochemistry and Biophysics, 277 (1). pp. 137-142. ISSN 0003-9861

Lusthof, Klaas J. and Mol de, Nicolaas J. and Janssen, Lambert H.M. and Egberink, Richard J.M. and Verboom, Willem and Reinhoudt, David N. (1990) Covalent binding studies on the 14C-labeled antitumour compound 2,5-bis(1-aziridinyl)-1,4-benzoquinone. Involvement of semiquinone radical in binding to DNA, and binding to proteins and bacterial macromolecules in situ. Chemico-Biological Interactions, 76 (2). pp. 193-209. ISSN 0009-2797

1989

Lusthof, Klaas J. and Mol de, Nicolaas J. and Janssen, Lambert H.M. and Verboom, Willem and Reinhoudt, David N. (1989) DNA alkylation and formation of DNA interstrand cross-links by potential antitumour 2,5-bis(1-aziridinyl)-1,4-benzoquinones. Chemico-Biological Interactions, 70 (3-4). pp. 249-262. ISSN 0009-2797