ART culture conditions change the probability of mouse embryo gestation through defined cellular and molecular responses

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Schwarzer, Caroline and Esteves, Telma Cristina and Arau´zo-Bravo, Marcos J. and Le Gac, Séverine and Nordhoff, Verena and Schlatt, Stefan and Boiani, Michele (2012) ART culture conditions change the probability of mouse embryo gestation through defined cellular and molecular responses. Human reproduction, 27 (9). pp. 2627-2640. ISSN 0268-1161

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Abstract:Do different human ART culture protocols prepare embryos differently for post-implantation development? ... Our data promote awareness that human ART culture media affect embryo development. Effects reported here in the mouse may apply also in human, because no ART medium presently available on the market has been optimized for human embryo development. The mouse embryo assay (MEA), which requires ART media to support at least 80 blastocyst formation, is in need of reform and should be extended to include post-implantation development.
Item Type:Article
Copyright:© 2012 Oxford University Press
Faculty:
Electrical Engineering, Mathematics and Computer Science (EEMCS)
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Link to this item:http://purl.utwente.nl/publications/81908
Official URL:http://dx.doi.org/10.1093/humrep/des223
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