Merging microfluidics and sonochemistry: towards greener and more efficient micro-sono-reactors

Fernandez Rivas, D. and Cintas, P. and Gardeniers, J.G.E. (2012) Merging microfluidics and sonochemistry: towards greener and more efficient micro-sono-reactors. Chemical communications, 48 (89). 10935 - 10947. ISSN 1359-7345

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Abstract:	Microfluidics enable the manipulation of chemical reactions using very small amounts of fluid, in channels with dimensions of tens to hundreds of micrometers; so-called microstructured devices, from which the iconic image of chips emerges. The immediate attraction of microfluidics lies in its greenness: use of small quantities of reagents and solvents, and hence less waste, a precise control of reaction conditions, integration of functionality for process intensification, safer and often faster protocols, reliable scale-up, and possibility of performing multiphase reactions. Among the limitations found in microfluidics the facile formation of precipitating products should be highlighted, and in this context, the search for efficient mass and energy transfers is a must. Such limitations have been partially overcome with the aid of ultrasound in conventional flow systems, and can now be successfully used in microreactors, which provide new capabilities. Novel applications and a better understanding of the physical and chemical aspects of sonochemistry can certainly be achieved by combining microfluidics and ultrasound. We will review this nascent area of research, paying attention to the latest developments and showing future directions, which benefit both from the existing microfluidic technology and sonochemistry itself. © 2012 The Royal Society of Chemistry.
Item Type:	Article
Copyright:	© 2012 RSC Publishing
Faculty:	Science and Technology (TNW)
Research Group:	Mesoscale Chemical Systems (MCS)
Link to this item:	http://purl.utwente.nl/publications/81519
Official URL:	http://dx.doi.org/10.1039/C2CC33920J
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