Detection of Pathogens with Impedance Analysis in a Lab on a Chip

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Wouden van der, E.J. and Super, M. and Ingber, D.E. and Berg van den, A. (2011) Detection of Pathogens with Impedance Analysis in a Lab on a Chip. Procedia Engineering, 25 . pp. 1465-1468. ISSN 1877-7058

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Abstract:In this work, we demonstrate an impedance approach to detect pathogens bound to magnetic beads. The approach was demonstrated with C-Albicans. We show that when an appropriate frequency is applied to two electrodes present in a microfluidic channel the impedance change in the detection volume can be used to distinguish between unbound beads and beads bound to pathogens. Furthermore, we present a model to relate measured impedance changes to an effective particle diameter.
Item Type:Article
Copyright:© 2011 Elsevier
Faculty:
Electrical Engineering, Mathematics and Computer Science (EEMCS)
Research Group:
Link to this item:http://purl.utwente.nl/publications/78790
Official URL:http://dx.doi.org/10.1016/j.proeng.2011.12.362
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Metis ID: 281615