A chep 2D fluorescence detection system for µM-sized beads on-Chip


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Segerink, Loes I. and Koster, Maarten J. and Sprenkels, Ad J. and Vermes, István and Berg van den, Albert (2011) A chep 2D fluorescence detection system for µM-sized beads on-Chip. In: 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences, μTAS 2011, 2-6 October 2011, Seattle, Washington.

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Abstract:In this paper a compact fluorescence detection system for on-chip analysis of μm-sized beads is presented. The system comprises a cheap optical pickup with integrated functionalities that are used for the detection. Furthermore some other optical components are added for the fluorescence detection. Another part of the system is the microfluidic chip which contains liquid channels and optical markers used for the autofocus and channel find algorithms. Within one minute the channel of interest is found and fluorescent beads are detected in the microchannel without the need for dynamic focusing, since a twodimensional scan across the channel width is performed.
Item Type:Conference or Workshop Item
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Electrical Engineering, Mathematics and Computer Science (EEMCS)
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Link to this item:http://purl.utwente.nl/publications/78657
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