Temperature-driven self-actuated microvalve for PCR


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Naito, Toyohiro and Arayanarakool, Rerngchai and Kaji, Noritada and Okamoto, Yukihiro and Tokeshi, Manubu and Le Gac, Séverine and Berg, Albert van den and Baba, Y. (2011) Temperature-driven self-actuated microvalve for PCR. In: 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences, μTAS 2011, 2-6 October 2011, Seattle, Washington (pp. pp. 248-250).

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Abstract:We report here a novel chamber-sealing valve that is self-actuated by pressure change during the cyclic temperature changes in PCR processes. Actuation of our valve requirs only a heating device employed for PCR. An UV-curable polymer is used as a device material and it allowed us to realize temperature-driven valve actuation as well as to fabricate a 3D device. The self-actuated microvalve achieves the effective sealing of microchamber for PCR even at 90ºC, which is essential to develop highly parallel PCR array device without any complicated actuator circuits.
Item Type:Conference or Workshop Item
Faculty:
Electrical Engineering, Mathematics and Computer Science (EEMCS)
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Link to this item:http://purl.utwente.nl/publications/78654
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