Temperature-driven self-actuated microvalve for PCR


Naito, Toyohiro and Arayanarakool, Rerngchai and Kaji, Noritada and Okamoto, Yukihiro and Tokeshi, Manubu and Le Gac, Séverine and Berg, Albert van den and Baba, Y. (2011) Temperature-driven self-actuated microvalve for PCR. In: 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences, μTAS 2011, 2-6 October 2011, Seattle, Washington (pp. pp. 248-250).

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Abstract:We report here a novel chamber-sealing valve that is self-actuated by pressure change during the cyclic temperature changes in PCR processes. Actuation of our valve requirs only a heating device employed for PCR. An UV-curable polymer is used as a device material and it allowed us to realize temperature-driven valve actuation as well as to fabricate a 3D device. The self-actuated microvalve achieves the effective sealing of microchamber for PCR even at 90ºC, which is essential to develop highly parallel PCR array device without any complicated actuator circuits.
Item Type:Conference or Workshop Item
Electrical Engineering, Mathematics and Computer Science (EEMCS)
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