Porous Ti6Al4V scaffold directly fabricating by rapid prototyping: preparation and in vitro experiment

Li, Jia Ping and Wijn de, Joost R. and Blitterswijk van, Clemens A. and Groot de, Klaas (2006) Porous Ti6Al4V scaffold directly fabricating by rapid prototyping: preparation and in vitro experiment. Biomaterials, 27 (8). pp. 1223-1235. ISSN 0142-9612

PDF
Restricted to UT campus only: Request a copy
1269Kb

Abstract:	Three-dimensional (3D) fiber deposition (3DF), a rapid prototyping technology, was successfully directly applied to produce novel 3D porous Ti6Al4V scaffolds with fully interconnected porous networks and highly controllable porosity and pore size. A key feature of this technology is the 3D computer-controlled fiber depositing of Ti6Al4V slurry at room temperature to produce a scaffold, consisting of layers of directionally aligned Ti6Al4V fibers. In this study, the Ti6Al4V slurry was developed for the 3D fiber depositing process, and the parameters of 3D fiber depositing were optimized. The experimental results show how the parameters influence the structure of porous scaffold. The potential of this rapid prototyping 3DF system for fabricating 3D Ti6Al4V scaffolds with regular and reproducible architecture meeting the requirements of tissue engineering and orthopedic implants is demonstrated.
Item Type:	Article
Copyright:	© 2006 Elsevier
Faculty:	Science and Technology (TNW)
Research Group:	Polymer Chemistry and BioMaterials (PBM)
Link to this item:	http://purl.utwente.nl/publications/78546
Official URL:	http://dx.doi.org/10.1016/j.biomaterials.2005.08.033
Export this item as:	BibTeX EndNote HTML Citation Reference Manager

Repository Staff Only: item control page

Metis ID: 229623