Outcome of Endometrial Cancer Stage IIIA with Adnexa or Serosal Involvement Only: clinical study


Jobsen, Jan J. and Naudin ten Cate, Lambert and Lybeert, Marnix L.M. and Scholten, Astrid and Steen-Banasik, Elzbieta M. van der and Palen, Job van der and Stenfert Kroese, Marika C. and Slot, Annerie and Schutter, Eltjo M. and Siesling, Sabine (2011) Outcome of Endometrial Cancer Stage IIIA with Adnexa or Serosal Involvement Only: clinical study. Obstetrics and Gynecology International, 2011 . p. 962518. ISSN 1687-9589

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Abstract:Objective. The aim of this study is to look at possible differences in outcome between serosa and adnexal involvement stage IIIA endometrial carcinoma. Methods. 67 patients with stage IIIA endometrial carcinoma were included, 46 with adnexal involvement and 21 with serosa. A central histopathological review was performed. Results. The 7-year locoregional failure rate was (LRFR) 2.2% for adnexal involvement and 16.0% for involvement of the serosa (P=.0522). The 7-year distant metastasis-free survival was 72.7% for adnexal involvement and 58.7% for serosa (P=.3994). The 7-year disease-specific survival (DSS) was 71.8% for patients with adnexal involvement and 75.4% for patients with serosa. Conclusion. Endometrial carcinoma stage IIIA with involvement of the adnexa or serosa showed to have a comparable disease-specific survival. Locoregional control was worse for serosa involvement compared to adnexa
Item Type:Article
Additional information:Open access article
Copyright:© 2011 The Author(s)
Faculty of Behavioural, Management and Social sciences (BMS)
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Link to this item:http://purl.utwente.nl/publications/77985
Official URL:http://dx.doi.org/10.1155/2011/962518
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