Controlled Encapsulation of Multiple Proteins in Virus Capsids

Share/Save/Bookmark

Minten, Inge J. and Hendriks, Linda J.A. and Nolte, Roeland J.M. and Cornelissen, Jeroen J.L.M. (2009) Controlled Encapsulation of Multiple Proteins in Virus Capsids. Journal of the American Chemical Society, 131 (49). pp. 17771-17773. ISSN 0002-7863

[img] PDF
Restricted to UT campus only
: Request a copy
3MB
Abstract:Multiple proteins can be bound within the Cowpea Chlorotic Mottle Virus capsid shell in an efficient and controlled manner by using heterodimeric coiled-coil peptide oligomers. Through genetic modification, these oligomers can be attached to the capsid protein and an enhanced green fluorescent protein (EGFP). In this way, the capsid proteins can be noncovalently bound to EGFP prior to the induction of the capsid assembly. Up to 15 EGFP proteins can be encapsulated per capsid in a controlled and efficient manner
Item Type:Article
Copyright:© 2009 American Chemical Society
Faculty:
Science and Technology (TNW)
Research Group:
Link to this item:http://purl.utwente.nl/publications/77783
Official URL:http://dx.doi.org/10.1021/ja907843s
Export this item as:BibTeX
EndNote
HTML Citation
Reference Manager

 

Repository Staff Only: item control page

Metis ID: 263228