Feasibility of quantitative determination of local optical absorbances in tissue-mimicking phantoms using acousto-optic sensing

Bratchenia, A. and Molenaar, R. and Kooyman, R.P.H. (2008) Feasibility of quantitative determination of local optical absorbances in tissue-mimicking phantoms using acousto-optic sensing. Applied Physics Letters, 92 (11). p. 113901. ISSN 0003-6951

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Abstract:	We have investigated the application of ultrasound modulation of coherent light for quantitative determination of local absorbances in tissue-mimicking phantoms. An Intralipid-based phantom model, which mimics a blood vessel in human tissue, was used. The detection technique was based on homodyne parallel speckle detection in transmission mode. Based on a comparison of experimental data and Monte Carlo simulations, a quantitative correlation between local absorbances of the phantom and the measured signal has been shown. The use of microsecond pulses of ultrasound and laser light resulted in a spatial resolution of the system of a few millimeters
Item Type:	Article
Copyright:	© 2008 American Institute of Physics
Faculty:	Science and Technology (TNW)
Research Group:	Nano-Biophysics (NBP)
Link to this item:	http://purl.utwente.nl/publications/76399
Official URL:	http://dx.doi.org/10.1063/1.2898884
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