A lab-on-a-chip system integrated with subwavelength periodic patterned metal surfaces for sers-based molecular identification biosensing

Jin, M. and Shui, L. and Otto, C. and Berg van den, A. and Carlen, E.T. (2010) A lab-on-a-chip system integrated with subwavelength periodic patterned metal surfaces for sers-based molecular identification biosensing. In: 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2010, 3-7 October 2010, Groningen, the Netherlands.

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Abstract:	We present a new lab-on-a-chip (LOC) analysis platform that is integrated with nanotextured surfaces with periodically spaced subwavelength nanogroove and nanopyramid structures with precisely defined pitch λg and separation gaps of ~2 nm spacing that form high density arrays of hot-spot scattering sites ideally suited for surface enhanced Raman scattering (SERS) and Raman spectroscopy using small sample volumes. The simple fabrication technique requires conventional lithography, wet anisotropic etching and a bonded polymer microfluidic layer. Measured Raman enhancement factors of G~106 from rhodamine 6G (R6G) on patterned Au surfaces with λg=200 nm are consistent with numerical calculations.
Item Type:	Conference or Workshop Item
Faculty:	Electrical Engineering, Mathematics and Computer Science (EEMCS) Science and Technology (TNW)
Research Group:	Biomedical and Environmental Sensor systems (BIOS) Medical Cell BioPhysics (MCBP)
Link to this item:	http://purl.utwente.nl/publications/75892
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