Recognizing DNA graphs is difficult


Pendavingh, Rudi and Schuurman, Petra and Woeginger, Gerhard J. (2003) Recognizing DNA graphs is difficult. Discrete Applied Mathematics, 127 (1). pp. 85-94. ISSN 0166-218X

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Abstract:DNA graphs are the vertex induced subgraphs of De Bruijn graphs over a four letter alphabet. In this paper, we prove the NP-hardness of various recognition problems for subgraphs of De Bruijn graphs; in particular, the recognition of DNA graphs is shown to be NP-hard. As a consequence, two open questions from a recent paper by B a ewicz et al. (Discrete Appl. Math. 98, (1999) 1) are answered in the negative.
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Copyright:© 2003 Elsevier
Electrical Engineering, Mathematics and Computer Science (EEMCS)
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