From fundamentals to applications: recent developments in atmospheric pressure photoionization mass spectrometry: review

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Bos, Suzanne J. and Leeuwen van, Suze M. and Karst, Uwe (2006) From fundamentals to applications: recent developments in atmospheric pressure photoionization mass spectrometry: review. Analytical and Bioanalytical Chemistry, 384 (1). pp. 85-99. ISSN 1618-2642

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Abstract:Only five years after the first publication on atmospheric pressure photoionization (APPI), this technique has evolved rapidly as a very useful complement to established ionization techniques for liquid chromatography/mass spectrometry (LC/MS). This is reflected in a rapidly increasing number of publications in this field. On the one hand, thorough studies into the photoionization mechanism have provided deep insights into the roles and influences of the solvent, the dopant and other additives. On the other hand, a large number of new and attractive applications have recently been introduced. New instrumental developments have resulted in combined APPI/ESI (PAESI) and APPI/APCI sources and a microfabricated APPI source. In this review, the most important developments within the field are summarized, focusing in particular on the applications of the technique.
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Copyright:© Springer
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Link to this item:http://purl.utwente.nl/publications/74293
Official URL:http://dx.doi.org/10.1007/s00216-005-0046-1
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