Strong and Reversible Monovalent Supramolecular Protein Immobilization

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Young, Jacqui F. and Nguyen, Hoang D. and Yang, Lanti and Huskens, Jurriaan and Jonkheijm, Pascal and Brunsveld, Luc (2010) Strong and Reversible Monovalent Supramolecular Protein Immobilization. ChemBioChem, 11 (2). pp. 180-183. ISSN 1439-4227

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Abstract:Proteins with an iron clasp: Site-selective incorporation of a ferrocene molecule into a protein allows for easy, strong, and reversible supramolecular protein immobilization through a selective monovalent interaction of the ferrocene with a cucurbit[7]uril immobilized on a gold surface. The proteins can be printed in a uniform monolayer that is resistant to washing conditions, but can be removed through competition with an excess of ferrocene ligand.
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Copyright:© 2009 Wiley
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Science and Technology (TNW)
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Link to this item:http://purl.utwente.nl/publications/72762
Official URL:http://dx.doi.org/10.1002/cbic.200900599
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