Imaging of small vessels using photoacoustics: an in vivo study


Siphanto, Ronald I. and Kolkman, Roy G.M. and Huisjes, Arjan and Pilatou, Magdalena C. and Mul, Frits F.M. de and Steenbergen, Wiendelt and Adrichem, Leon N.A. van (2004) Imaging of small vessels using photoacoustics: an in vivo study. Lasers in Surgery and Medicine, 35 (5). pp. 354-362. ISSN 0196-8092

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Abstract:Background and Objectives
The ability to correctly visualize the architectural arrangement of microvasculature is valuable to many diverse fields in medicine. In this study, we applied photoacoustics (PA) to obtain high-resolution images of submillimeter blood vessels. -
Study Design/Materials and Methods: Short laser pulses are used to generate ultrasound from superficial blood vessels in several animal models. From these ultrasound waves the interior of blood vessels can be reconstructed. -
Result : We present results from a novel approach based on the PA principle that allows specific in vivo visualization of dermal blood vessels without the use of contrast agents or ionizing radiation. =
Conclusions: We show PA images of externalized blood vessels and demonstrate in vivo PA imaging of vasculature through layers of skin varying in thickness. Lasers Surg. Med. 35:354-362, 2004.
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Copyright:© 2004 Wiley InterScience
Science and Technology (TNW)
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Metis ID: 220644