New approaches for fabrication of microfluidic capillary electrophoresis devices with on-chip conductivity detection

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Guijt, Rosanne M. and Baltussen, Erik and Steen van der, Gert and Schasfoort, Richard B.M. and Schlautmann, Stefan and Billiet, Hugo A.H. and Frank, Johannes and Dedem van, Gijs W.K. and Berg van den, Albert (2001) New approaches for fabrication of microfluidic capillary electrophoresis devices with on-chip conductivity detection. Electrophoresis, 22 (2). pp. 235-241. ISSN 0173-0835

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Abstract:In practice, microfluidic systems are based on the principles of capillary electrophoresis (CE), for a large part due to the simplicity of electroosmotic pumping. In this contribution, a universal conductivity detector is presented that allows detection of charged species down to the µM level. Additionally, powderblasting is presented as a novel technique for direct etching of microfluidic networks. This method allows creation of features down to 50 µm with a total processing time (design to device) of less than one day. The performance of powderblasted devices with integrated conductivity detection is illustrated by the separation of lithium, sodium, and potassium ions and that of fumaric, malic, and citric acid.
Item Type:Article
Copyright:© 2001 Wiley InterScience
Faculty:
Science and Technology (TNW)
Electrical Engineering, Mathematics and Computer Science (EEMCS)
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Link to this item:http://purl.utwente.nl/publications/71822
Official URL:http://dx.doi.org/10.1002/1522-2683(200101)22:2<235::AID-ELPS235>3.0.CO;2-O
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