Combined Raman spectroscopy and optical coherence tomography device for tissue characterization

Patil, Chetan A. and Bosschaart, Nienke and Keller, Matthew D. and Leeuwen van, Ton G. and Mahadevan-Jansen, Anita (2008) Combined Raman spectroscopy and optical coherence tomography device for tissue characterization. Optics Letters, 33 (10). pp. 1135-1137. ISSN 0146-9592

PDF
Restricted to UT campus only: Request a copy
416Kb

Abstract:	coherence tomography (OCT) along a common optical axis. The device enhances application of both RS and OCT by precisely guiding RS acquisition with OCT images while also compensating for the lack of molecular specificity in OCT with the biochemical specificity of RS. We characterize the system performance and demonstrate the capability to identify structurally ambiguous features within an OCT image with RS in a scattering phantom, guide acquisition of RS from a localized malignancy in ex vivo breast tissue, and perform in vivo tissue analysis of a scab.
Item Type:	Article
Copyright:	© 2008 Optical Society of America
Faculty:	Science and Technology (TNW)
Research Group:	Biomedical Photonic Imaging (BMPI)
Link to this item:	http://purl.utwente.nl/publications/71716
Official URL:	http://dx.doi.org/10.1364/OL.33.001135
Export this item as:	BibTeX EndNote HTML Citation Reference Manager

Show download statistics for this publication

Repository Staff Only: item control page

Metis ID: 252429