Photo-crosslinking of functionalised lactide oligomers for the fabrication of osteochondral tissue engineering scaffolds

Melchels, F.P.W. and Grijpma, D.W. and Feijen, J. (2006) Photo-crosslinking of functionalised lactide oligomers for the fabrication of osteochondral tissue engineering scaffolds. Journal of Controlled Release, 116 (2). e98-e100. ISSN 0168-3659

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Abstract:	In the fabrication of osteochondral tissue engineering scaffolds, the two distinct tissues impose different requirements on the architecture. Stereo-lithography is a rapid prototyping method that can be utilised to make 3D constructs with high spatial control by radical photo-polymerisation. In this study, biodegradable resins are developed that can be applied in stereo-lithography. Photo-crosslinked poly(lactide) networks with varying physical properties were synthesised, and by photo-polymerising in the presence of leachable particles porous scaffolds could be prepared as well.
Item Type:	Article
Copyright:	© 2006 Elsevier
Faculty:	Science and Technology (TNW)
Research Group:	Biomaterials Science and Technology (BST) Polymer Chemistry and BioMaterials (PBM)
Link to this item:	http://purl.utwente.nl/publications/71114
Official URL:	http://dx.doi.org/10.1016/j.jconrel.2006.09.070
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