Protein release from injectable stereocomplexed hydrogels based on PEG–PDLA and PEG–PLLA star block copolymers

Hiemstra, C. and Zhong, Z.Y. and Tomme Van, S.R. and Hennink, W.E. and Dijkstra, P.J. and Feijen, J. (2006) Protein release from injectable stereocomplexed hydrogels based on PEG–PDLA and PEG–PLLA star block copolymers. Journal of Controlled Release, 116 (2). e19-e21. ISSN 0168-3659

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Abstract:	The release of two model proteins, lysozyme and immunoglobulin G (IgG) from injectable, fast gelling, biodegradable hydrogels composed of PEG–PLLA and PEG–PDLA star block copolymers was investigated. Lysozyme was quantitatively released in 10 days. The release of IgG was slower and after 20 days 40–60% was released depending on the composition of the gel.
Item Type:	Article
Copyright:	Elsevier B.V.
Faculty:	Science and Technology (TNW)
Research Group:	Polymer Chemistry and BioMaterials (PBM)
Link to this item:	http://purl.utwente.nl/publications/71107
Official URL:	http://dx.doi.org/10.1016/j.jconrel.2006.09.028
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