Antithrombin activity of a polyelectrolyte synthesized from cis-1,4-polyisoprene

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Beugeling, T. and Does, L. van der and Bantjes, A. and Sederel, W.L. (1974) Antithrombin activity of a polyelectrolyte synthesized from cis-1,4-polyisoprene. Journal of Biomedical Materials Research, 8 (6). pp. 375-379. ISSN 0021-9304

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Abstract:A polyelectrolyte synthesized from cis-1,4-polyisoprene, containing aminosulfonate and carboxylate groups was shown to have an anticoagulant activity of about 1/30 compared with heparin. Because the substance prevents the coagulation of plasma in the presence of thrombin it is assumed that it acts as an antithrombin.
Item Type:Article
Copyright:© 1974 Wiley InterScience
Link to this item:http://purl.utwente.nl/publications/70742
Official URL:http://dx.doi.org/10.1002/jbm.820080605
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