Label-free Enzyme Sensing with Grated Silicon Photonic Wire


Kauppinen, L.J. and Dijkstra, M. and Hoekstra, H.J.W.M. and Ridder, R.M. de (2009) Label-free Enzyme Sensing with Grated Silicon Photonic Wire. In: 2009 Annual Symposium of the IEEE Photonics Benelux Chapter, 05-06 Nov 2009, Brussels, Belgium (pp. pp. 41-44).

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Abstract:We have investigated the label-free biosensing properties of grated silicon photonic wire (GSPW) waveguides with cross-sectional dimensions of 350 nm x 220 nm, fabricated using a 248-nm deep UV lithography process. The steep edges of the optical transmission spectrum of the GSPW enable detection of very small spectral shift, hence of small index changes.
To obtain an antibody layer for the biosensing experiment, an immobilization process is required. We followed the standard immobilization process developed by Imenz B.V.
The antibody immobilization process and the binding process of enzymes on an immobilized antibody layer have been monitored with the GSPW based sensor.
Item Type:Conference or Workshop Item
Electrical Engineering, Mathematics and Computer Science (EEMCS)
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