Three-dimensional photonic devices fabricated by ultrafast lasers for optical sensing in lab-on-a-chip


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Martínez Vázquez, R. and Osellame, R. and Crespi, A. and Dongre, C. and Hoekstra, H.J.W.M. and Pollnau, M. and Vlekkert van den, H. and Weeghel van, R. and Watts, P. and Ramponi, R. and Cerullo, G. (2009) Three-dimensional photonic devices fabricated by ultrafast lasers for optical sensing in lab-on-a-chip. In: Commercial and Biomedical Applications of Ultrafast Lasers IX. Proceedings of SPIE, 7203 . SPIE, Society of Photo-Optical Instrumentation Engineers, Bellinham, Washington, USA, p. 720313. ISBN 9780819474490

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Abstract:We report on the use of femtosecond laser pulses to fabricate photonic devices (waveguides and interferometers) inside commercial CE chips without affecting the manufacturing procedure of the microfluidic part of the device. The fabrication of single waveguides intersecting the channels allows one to perform absorption or Laser Induced Fluorescence (LIF) sensing of the molecules separated inside the microchannels. Microfluidic channels, with access holes, are fabricated using femtosecond laser irradiation followed by chemical etching. Mach-Zehnder interferometers are used for label-free sensing of the samples flowing in the microfluidic channels by means of refractive index changes detection.
Item Type:Book Section
Copyright:© 2009 SPIE
Faculty:
Electrical Engineering, Mathematics and Computer Science (EEMCS)
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Link to this item:http://purl.utwente.nl/publications/69937
Official URL:http://dx.doi.org/10.1117/12.809142
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