A Method towards Automated Thrombolysis in Myocardial Infarction (TIMI) Frame Counting Using 3D Reconstruction

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Brinke, G.A. ten and Slump, C.H. and Storm, C.J. and Stoel, M.G. (2009) A Method towards Automated Thrombolysis in Myocardial Infarction (TIMI) Frame Counting Using 3D Reconstruction. Computers in Cardiology, 36 . pp. 653-656. ISSN 0276-6574

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Abstract:Coronary stenosis is often assessed using planar X-ray angiography while injecting contrast agent. The data obtained during the intervention can be used to assess coronary flow velocity by tracking the contrast agent. The contrast flow can be used to estimate the functional behavior of the coronary arteries using TIMI frame count (TFC). In this paper we propose and evaluate a method towards the automation of TFC. The method creates a two dimensional map of the contrast agent in which the opacification of the vessel centerline is plotted against time. This map is used to find the velocity of the contrast agent and subsequently the TFC. The vessel centerline is found using the Fast Marching Method to find the lowest cost path between the catheter point and the manually selected endpoint of the vessel. Results from 22 patients show that the algorithm is able to estimate TFC correctly in 13 of 22 cases within the intra observer error range of 5 frames compared to manual TFC.
Item Type:Article
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Electrical Engineering, Mathematics and Computer Science (EEMCS)
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Link to this item:http://purl.utwente.nl/publications/69863
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