ISFET based enzyme sensors

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Schoot van der, Bart H. and Bergveld, Piet (1987) ISFET based enzyme sensors. Biosensors, 3 (3). pp. 161-186. ISSN 0265-928X

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Abstract:This paper reviews the results that have been reported on ISFET based enzyme sensors. The most important improvement that results from the application of ISFETs instead of glass membrane electrodes is in the method of fabrication. Problems with regard to the pH dependence of the response and the dynamic range as well as the influence of the sample buffer capacity have not been solved. As a possible solution we introduce a coulometric system that compensates for the analyte buffer capacity. If the pH in the immobilized enzyme layer is thus controlled, the resulting pH-static enzyme sensor has an output that is independent of the sample pH and buffer capacity and has an expanded linear range.
Item Type:Article
Copyright:© 1988 Elsevier Science
Faculty:
Electrical Engineering, Mathematics and Computer Science (EEMCS)
Link to this item:http://purl.utwente.nl/publications/69637
Official URL:http://dx.doi.org/10.1016/0265-928X(87)80025-1
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