Point-of-care lithium monitoring in whole blood using a disposable, prefilled and ready-to-use capillary electrophoresis microchip


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Kohlheyer, Dietrich and Eijkel, Jan and Lenk, Stefan and Floris, Arjan and Staal, Steven and Berg van den, Albert (2009) Point-of-care lithium monitoring in whole blood using a disposable, prefilled and ready-to-use capillary electrophoresis microchip. In: MicroTAS 2009, Thirteenth International Conference on Miniaturized Systems for Chemistry and Life Sciences, 1-5 Nov 2009, Jeju, Korea.

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Abstract:This paper describes a microfluidic capillary electrophoresis device with integrated conductivity detection. The device satisfies all major requirements for pointof-care testing, i.e., simple handling, low sample volume, fast measurements, clear readout, and inexpensive disposable cartridge usage. The system is currently being utilized and commercialized for monitoring lithium in whole blood, however, can potentially be applied to various other ions present in blood, urine or other bodily fluids. The chip contains a single inlet only and will be shipped prefilled with background electrolyte, sealed and blistered; ready for use at the patient’s place. A single droplet of blood is required to be placed inside the cartridge to perform the analysis typically within a couple of minutes.
Item Type:Conference or Workshop Item
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Electrical Engineering, Mathematics and Computer Science (EEMCS)
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Link to this item:http://purl.utwente.nl/publications/69428
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