Interaction of cultured human endothelial cells with polymeric surfaces of different wettabilities

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Wachem van, P.B. and Beugeling, T. and Feijen, J. and Bantjes, A. and Detmers, J.P. and Aken van, W.G. (1985) Interaction of cultured human endothelial cells with polymeric surfaces of different wettabilities. Biomaterials, 6 (6). pp. 403-408. ISSN 0142-9612

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Abstract:The in vitro interaction of human endothelial cells (HEC) and polymers with different wettabilities in culture medium containing serum was investigated. Optimal adhesion of HEC generally occurred onto moderately wettable polymers. Within a series of cellulose type of polymers the cell adhesion increased with increasing contact angle of the polymer surfaces. Proliferation of HEC occurred when adhesion was followed by progressive flattening of the cells.

Our results suggest that moderately wettable polymers exhibit a serum and/or cellular protein adsorption pattern that is favourable for growth of HEC.
Item Type:Article
Copyright:© 1985 Elsevier Science
Faculty:
Science and Technology (TNW)
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Link to this item:http://purl.utwente.nl/publications/69420
Official URL:http://dx.doi.org/10.1016/0142-9612(85)90101-2
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