Adsorption of a synthetic heparinoid polyelectrolyte on an ion-exchanging surface

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Froehling, Peter E. and Bantjes, Adriaan and Kolar, Z. (1977) Adsorption of a synthetic heparinoid polyelectrolyte on an ion-exchanging surface. Journal of Colloid and Interface Science, 62 (1). pp. 35-39. ISSN 0021-9797

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Abstract:The adsorption of a synthetic heparinoid polyelectrolyte on poly(vinylchloride) previously treated with tridodecylmethylammonium chloride (TDMAC) was studied using radiotracer techniques to provide a more quantitative picture of antithrombogenic surface coatings. 125I-labeled polyelectrolyte was used for overall adsorption measurements. Experiments with 36Cl-labeled TDMAC yielded information on actually adsorbed polyelectrolyte segments in good agreement with existing theory. A large excess of free dangling segments was found. In the presence of NaCl the total adsorption was diminished, although no desorption occurred on treatment of adsorbates with 0.15 M NaCl or blood plasma.
Item Type:Article
Copyright:© 1977 Elsevier Science
Link to this item:http://purl.utwente.nl/publications/68020
Official URL:http://dx.doi.org/10.1016/0021-9797(77)90062-5
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