Integration of porous layers in ordered pillar arrays for liquid chromatography

Share/Save/Bookmark

Malsche de, Wim and Clicq, David and Verdoold, Vincent and Gzil, Piotr and Desmet, Gert and Gardeniers, Han (2007) Integration of porous layers in ordered pillar arrays for liquid chromatography. Lab on a Chip, 7 (12). pp. 1705-1711. ISSN 1473-0197

[img]PDF
Restricted to UT campus only
: Request a copy
521Kb
Abstract:The present paper describes a method for the production of partly porous micro-pillars in columns suitable for use in liquid chromatography. These layers increase the available surface at least two orders of magnitude without destroying the huge benefits of the ordered nature of the system. A process flow was developed that enabled us to create a 550 nm thick porous layer on the pillar array in a sealed channel configuration, withstanding pressures up to at least 70 bar. Measuring band broadening under non-retained conditions, only a modest increase in plate height was observed in the porous pillar array as compared to that in a non-porous pillar array. The homogeneity of the layers was demonstrated using an optical microscope and SEM pictures and by monitoring peak velocities at constant pressures. The internal porosity was determined using particles with a diameter larger than the mesopores in combination with a dye that could penetrate into the pores.
Item Type:Article
Copyright:© 2007 Royal Society of Chemistry
Faculty:
Science and Technology (TNW)
Research Group:
Link to this item:http://purl.utwente.nl/publications/67274
Official URL:http://dx.doi.org/10.1039/b710507j
Export this item as:BibTeX
EndNote
HTML Citation
Reference Manager

 

Repository Staff Only: item control page

Metis ID: 245009