Towards fast plasma and blood cell separation - pattern and arrangement investigation of post arrays used in deterministic hydrodynamics
Li, J. and Le Gac, S. and van den Berg, A. (2008) Towards fast plasma and blood cell separation - pattern and arrangement investigation of post arrays used in deterministic hydrodynamics. In: 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, 12-16 Oct 2008, San Diego, California.
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|Abstract:||We show that both the post pattern and arrangement have an influence on the|
cell movement (zigzag vs. bump mode) in deterministic hydrodynamics while the
current theory is limited to one parameter, the array row shift ε for cylindrical posts.
Besides, a new mechanism of cell movement, the “stair movement” mechanism is
reported; thereby, cells are laterally shifted across stream lines in a laminar flow.
Our new designs greatly shorten the separation length (~1 mm vs. ~20 cm) for fractionating
cells compared to previous works , and consequently the separation
time, and alleviate any cell clogging problem
|Item Type:||Conference or Workshop Item|
Electrical Engineering, Mathematics and Computer Science (EEMCS)
|Link to this item:||http://purl.utwente.nl/publications/62719|
|Export this item as:||BibTeX|
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