Towards fast plasma and blood cell separation - pattern and arrangement investigation of post arrays used in deterministic hydrodynamics

Li, J. and Le Gac, S. and van den Berg, A. (2008) Towards fast plasma and blood cell separation - pattern and arrangement investigation of post arrays used in deterministic hydrodynamics. In: 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, 12-16 Oct 2008, San Diego, California.

PDF
Restricted to UT campus only: Request a copy
377Kb

Abstract:	We show that both the post pattern and arrangement have an influence on the cell movement (zigzag vs. bump mode) in deterministic hydrodynamics while the current theory is limited to one parameter, the array row shift ε for cylindrical posts. Besides, a new mechanism of cell movement, the “stair movement” mechanism is reported; thereby, cells are laterally shifted across stream lines in a laminar flow. Our new designs greatly shorten the separation length (~1 mm vs. ~20 cm) for fractionating cells compared to previous works [1], and consequently the separation time, and alleviate any cell clogging problem
Item Type:	Conference or Workshop Item
Faculty:	Electrical Engineering, Mathematics and Computer Science (EEMCS)
Research Group:	Biomedical and Environmental Sensor systems (BIOS)
Link to this item:	http://purl.utwente.nl/publications/62719
Export this item as:	BibTeX EndNote HTML Citation Reference Manager

Show download statistics for this publication

Repository Staff Only: item control page

Metis ID: 255466