High flow rate microsieve for bio medical applications


Rijn, C.J.M. van and Nijdam, W. and Elwenspoek, M.C. (1995) High flow rate microsieve for bio medical applications. Proceedings of the ASME Dynamic Systems and Control Division, 57-2 . pp. 995-1000. ISSN 0022-0434

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Abstract:A new composite filtration membrane having a thin filtration or sieving layer has been developed. This filtration membrane with a high pore density and a narrow pore size distribution on a macro porous support shows good separation behaviour and a high flow rate. Because of the construction method, the openings are no longer restricted to circular shapes, but can be chosen freely. In this case a microsieve with slits will be presented. The main advantage of a slit over a circular opening is the higher flow rate. In this paper a process description for manufacturing is presented and the flow rate behaviour of the membrane with slits will be compared with a membrane with circular perforations. Also results of experiments of leukocyte removal from erythrocyte concentrates with a silicon microsieve will be discussed.
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Electrical Engineering, Mathematics and Computer Science (EEMCS)
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