Parkinsonian movements in model and experiment


Heida, T. and Moroney, R. and Geelen, J.A.G. (2007) Parkinsonian movements in model and experiment. In: 8th world congres INS (International Neuromodulation Society) and 11th annual meeting NANS (North American Neuromodulation Society), 9-12 dec 2007, Acapulco, Mexico (pp. pp. 110-111).

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Abstract:Parkinson's disease (PD) is known to originate from a degeneration of dopaminergic neurons in the substania nigra. One of the most debilitating aspects of PD is the inability to initiate and execute voluntary movements (bradykinesia and akinesia). PD patients are particularly impaired in the performance of complex movements, e.g. simultaneous and sequiential motor tasks... The goal of the current research is to develop a methematical model of the functional scheme of the 'motor' basal ganglia-thalamocortical circuit. In addition, an experimental study is set up to investigate movements performed by PD patients, and the effectiveness of DBS.
Item Type:Conference or Workshop Item
Electrical Engineering, Mathematics and Computer Science (EEMCS)
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Metis ID: 245998