Discovery of recurrent multiple brain states in non-convulsive status epilepticus

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Putten van, Michel J.A.M and Putten van, Maurice H.P.M. (2007) Discovery of recurrent multiple brain states in non-convulsive status epilepticus. Clinical Neurophysiology, 118 (12). pp. 2798-2804. ISSN 1388-2457

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Abstract:Objective: We study burst-like patterns of epileptiform discharges in non-convulsive status epilepticus (SE). - Methods: Epileptiform burst-like transients were identified by estimating the amplitude envelope of the EEG signal, and recurrence and similarities were identified by pairwise matching in the time-domain. - Results: We identified similarities in the onset of a significant fraction of the epileptiform bursts, and a bimodal distribution of the burst durations. - Conclusions: Bursts of epileptiform discharges during a non-convulsive SE are manifestations of multiple patterns of recurring brain states.

Significance
Quantitative description of ictal phenomena in epilepsy and status epilepticus adds to the knowledge of abnormal brain behavior and may assist in improved patient care.
Item Type:Article
Copyright:© 2007 Elsevier
Faculty:
Science and Technology (TNW)
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Link to this item:http://purl.utwente.nl/publications/62032
Official URL:http://dx.doi.org/10.1016/j.clinph.2007.08.026
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