Latency dependent development of related firing patterns of cultured cortical neurons


Share/Save/Bookmark

Feber, Joost le and Pelt, Jaap van and Rutten, Wim (2007) Latency dependent development of related firing patterns of cultured cortical neurons. In: 29th Annual International Conference of the IEEE on Engineering in Medicine and Biology Society, EMBS 2007, 22-26 August 2007, Lyon, France (pp. pp. 3000-3003).

[img] PDF
Restricted to UT campus only
: Request a copy
301kB
Abstract:Networks of cortical neurons were grown over multi electrode arrays to enable simultaneous measurement of signals from multiple neurons. We described functional connectivity in these networks by relationships be¬tween individual electrodes, based on conditional firing probabilities. In this study we investigated periods in which the strength of a relation¬ship monotonously increased (strengthening) or decreased (weakening) during periods of 24 or 10 hours. We observed a slightly increased incidence of latencies up to 25 ms during strengthening, while these latencies rarely occurreded during weakening. Next, it appeared that relationships tended to strengthen more than average in periods with latencies in the range 5-30 ms, whereas strengthening was significantly less than average in latencies 40-65 ms.
Item Type:Conference or Workshop Item
Faculty:
Electrical Engineering, Mathematics and Computer Science (EEMCS)
Research Group:
Link to this item:http://purl.utwente.nl/publications/62012
Export this item as:BibTeX
EndNote
HTML Citation
Reference Manager

 

Repository Staff Only: item control page

Metis ID: 245768