Carotenoids located in human lymphocyte subpopulations and natural killer cells by Raman microspectroscopy

Share/Save/Bookmark

Puppels, G.J. and Garritsen, H.S.P. and Kummer, J.A. and Greve, Jan (1993) Carotenoids located in human lymphocyte subpopulations and natural killer cells by Raman microspectroscopy. Cytometry Part A, 14 (3). pp. 251-256. ISSN 0196-4763

[img]
Preview
PDF
598Kb
Abstract:The presence and subcellular location of carotenoids in human lymphocyte sub-populations (CD4+, CD8+, T-cell receptor-γδ+, and CD19+ ) and natural killer cells (CD16+ ) were studied by means of Raman microspectroscopy. In CD4+ lymphocytes a high concentration (10-3M) of carotenoids was found in the Gall body. In CD8+ lymphocytes, T-cell-receptor-γδ+ lymphocytes and in natural killer cells carotenoids appeared to be concentrated (10-4M) in the Golgi complex. The concentration of carotenoids in CD19+ lymphocytes was found to be below the present detection limit, which is ~10-6 to 10-5 M. The results provide new possibilities to investigate the mechanism(s) behind the suggested protective role of carotenoids against the development of cancers.
Item Type:Article
Copyright:© 1993 Wiley-Liss
Research Group:
Link to this item:http://purl.utwente.nl/publications/60728
Official URL:http://dx.doi.org/10.1002/cyto.990140303
Export this item as:BibTeX
EndNote
HTML Citation
Reference Manager

 

Repository Staff Only: item control page

Metis ID: 129491