Transient Binding and Dissipation in Cross-Linked Actin Networks

Share/Save/Bookmark

Lieleg, O. and Claessens, M.M.A.E. and Luan, Y. and Bausch, A.R. (2008) Transient Binding and Dissipation in Cross-Linked Actin Networks. Physical Review Letters, 101 (10). p. 108101. ISSN 0031-9007

[img]
Preview
PDF
216Kb
Abstract:In contrast with entangled actin solutions, transiently cross-linked actin networks can provide highly elastic properties while still allowing for local rearrangements in the microstructure-on biological relevant time scales. Here, we show that thermal unbinding of transient cross-links entails local stress relaxation and energy dissipation in an intermediate elasticity dominated frequency regime. We quantify the viscoelastic response of an isotropically cross-linked actin network by experimentally tuning the off rate of the transiently cross-linking molecules, their density, and the solvent viscosity. We reproduce the measured frequency response by a semiphenomenological model that is predicated on microscopic unbinding events.
Item Type:Article
Copyright:© 2008 American Physical Society
Faculty:
Science and Technology (TNW)
Research Group:
Link to this item:http://purl.utwente.nl/publications/59955
Official URL:http://dx.doi.org/10.1103/PhysRevLett.101.108101
Export this item as:BibTeX
EndNote
HTML Citation
Reference Manager

 

Repository Staff Only: item control page

Metis ID: 250787