Spectral analysis and a closest tree method for genetic sequences


Steel, M.A. and Hendy, M.D. and Székely, L.A. and Erdös, P.L. (1992) Spectral analysis and a closest tree method for genetic sequences. Applied Mathematics Letters, 5 (6). pp. 63-67. ISSN 0893-9659

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Abstract:We describe a new method for estimating the evolutionary tree linking a collection of species from their aligned four-state genetic sequences. This method, which can be adapted to provide a branch-and-bound algorithm, is statistically consistent provided the sequences have evolved according to a standard stochastic model of nucleotide mutation. Our approach exploits a recent group-theoretic description of this model.
Item Type:Article
Copyright:© 1992 Elsevier Science
Link to this item:http://purl.utwente.nl/publications/57456
Official URL:https://doi.org/10.1016/0893-9659(92)90016-3
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