Osmotic shrinkage of giant egg-lecithin vesicles


Boroske, E. and Elwenspoek, M. and Helfrich, W. (1981) Osmotic shrinkage of giant egg-lecithin vesicles. Biophysical Journal, 34 (1). pp. 95-109. ISSN 0006-3495

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Abstract:Osmotic shrinkage of giant egg-lecithin vesicles was observed by phase- contrast microscopy. The vesicles remained or became spherical when shrinking. Small and thick-walled vesicles formed visible fingers attached to the sphere. The water permeability of the single bilayer was found to be 41 micrometers/s. A variety of observations indicate that osmosis induces a parallel lipid flow between the monolayers of the bilayer, leading to a strong positive spontaneous curvature. They also suggest the formation of mostly submicroscopic daughter vesicles. The estimated coupling constant, 2 . 10(-6) mol/mol, is large enough to be biologically significant.
Item Type:Article
Copyright:© 1981 Biophysical Society
Electrical Engineering, Mathematics and Computer Science (EEMCS)
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Link to this item:http://purl.utwente.nl/publications/56042
Official URL:https://doi.org/10.1016/S0006-3495(81)84839-4
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