Ultrasound-induced microbubble coalescence


Postema, Michiel and Marmottant, Philippe and Lancée, Charles T. and Hilgenfeldt, Sascha and Jong, Nico de (2004) Ultrasound-induced microbubble coalescence. Ultrasound in Medicine and Biology, 30 (10). pp. 1337-1344. ISSN 0301-5629

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Abstract:We studied the interaction of ultrasound contrast agent bubbles coated with a layer of lipids, driven by 0.5 MHz ultrasound. High-speed photography on the submicrosecond timescale reveals that some bubbles bounce off each other, while others show very fast coalescence during bubble expansion. This fast coalescence cannot be explained by dissipation-limited film drainage rates. We conclude that the lipid shell ruptures upon expansion, exposing clean free bubble interfaces that support plug flow profiles in the film and inertia-limited drainage whose time scales match those of the observed coalescence.
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Copyright:© 2004 World Federation for Ultrasound in Medicine & Biology
Science and Technology (TNW)
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Link to this item:http://purl.utwente.nl/publications/50154
Official URL:https://doi.org/10.1016/j.ultrasmedbio.2004.08.008
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