A Simple Approach to Sensor Discovery and Fabrication on Self-Assembled Monolayers on Glass

Basabe Desmonts, Lourdes and Beld, Joris and Zimmerman, Rebecca S. and Hernando, Jordi and Mela, Petra and Garcia-Parajo, Maria F. and Hulst van, Niek F. and Berg van den, Albert and Reinhoudt, David N. and Crego Calama, Mercedes (2004) A Simple Approach to Sensor Discovery and Fabrication on Self-Assembled Monolayers on Glass. Journal of the American Chemical Society, 126 (23). pp. 7293-7299. ISSN 0002-7863

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Abstract:	Self-assembled monolayers (SAMs) on glass were used as a platform to sequentially deposit fluorophores and small molecules for ion sensing. The preorganization provided by the surface avoids the need for complex receptor design, allowing for a combinatorial approach to sensing systems based on small molecules. The resulting libraries are easily measured and show varied responses to a series of both cations and anions. This technology is transferable from the macro- to the microscale both via microcontact printing (CP), where the fluorophore is printed onto a glass surface, and via direct attachment of the fluorophore to microchannel walls. The ease of miniaturization of this technology may make the generation of a wide variety of simple yet efficient microarrays possible.
Item Type:	Article
Copyright:	© 2004 American Chemical Society
Faculty:	Electrical Engineering, Mathematics and Computer Science (EEMCS)
Research Group:	Biomedical and Environmental Sensor systems (BIOS)
Link to this item:	http://purl.utwente.nl/publications/49548
Official URL:	http://dx.doi.org/10.1021/ja049901o
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