Electroosmotic guiding of sample flows in a laminar flow chamber


Besselink, Geert A.J. and Vulto, Paul and Lammertink, Rob G.H. and Schlautmann, Stefan and Berg, Albert van den and Olthuis, Wouter and Engbers, Gerard H.M. and Schasfoort, Richard B.M. (2004) Electroosmotic guiding of sample flows in a laminar flow chamber. Electrophoresis, 25 (21-22). pp. 3705-3711. ISSN 0173-0835

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Abstract:The so-called address-flow principle is described: a valveless, electroosmotically driven technology used for controlling the stream profile in a laminar flow chamber. The method is explained, and a theoretical description and experimental verification are presented. Adjustment of the flow of two electroosmotically controlled guiding streams, running parallel to a central sample stream, can be used for positioning the sample stream in the dimension perpendicular to the flow direction. The results presented show that address-flow microfluidics allow easy and accurate control of sample stream position and width. The electroosmotic flow (EOF)-controlled guiding of microfluidic flows described in this paper, is a new unit operation that might aid in separation and collection in microfluidic devices. One possible application of addressflow microfluidics is guiding of capillary electrophoresis-separated components over a multisensor array, in order to perform affinity assays.
Item Type:Article
Copyright:© 2004 WILEY-VCH
Science and Technology (TNW)
Electrical Engineering, Mathematics and Computer Science (EEMCS)
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Link to this item:http://purl.utwente.nl/publications/48145
Official URL:https://doi.org/10.1002/elps.200406033
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Metis ID: 219384