Microtechnologies and nanotechnologies for single-cell analysis

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Andersson, Helene and Berg, Albert van den (2004) Microtechnologies and nanotechnologies for single-cell analysis. Current Opinion in Biotechnology, 15 (1). pp. 44-49. ISSN 0958-1669

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Abstract:Many efforts are currently underway to try and mimic the properties of single cells with the aim of designing chips that are as efficient as cells. However, cells are nature’s nanotechnology engineering at the scale of atoms and molecules, and it might be better to envision a microchip that utilizes a single cell as an experimentation platform. A novel, so-called laboratory-in-a-cell concept has been described, where advantage is taken of micro- and nanotechnological tools to enable precise control of the biochemical cellular environment; these tools also offer the possibility to analyse the composition of single cells. Methods for single-cell handling and analysis are being developed and will be required for this concept to progress further.
Item Type:Article
Copyright:© 2004 Elsevier
Faculty:
Electrical Engineering, Mathematics and Computer Science (EEMCS)
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Link to this item:http://purl.utwente.nl/publications/47829
Official URL:http://dx.doi.org/10.1016/j.copbio.2004.01.004
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