High Signal to Noise Ratio in Low Field NMR on Chip, Simulations and Experimental Results


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Wensink, H. and Hermes, D.C. and Berg van den, A. (2004) High Signal to Noise Ratio in Low Field NMR on Chip, Simulations and Experimental Results. In: 17th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2004, January 25-29 , 2004, Maastricht, The Netherlands.

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Abstract:A /spl mu/fluidic chip with integrated microcoil was developed for nuclear magnetic resonance (NMR) spectroscopy on limited volume samples (nanoliters range). This chip will be used for the online monitoring of micro chemical reactions. Design rules for the microcoil to achieve the best signal to noise ratio (SNR) were obtained by finite element simulation. For pure water in a low field NMR magnet (60 MHz., i.e. 1.4 Tesla) a SNR of 550 was achieved which is to our knowledge higher than any other /spl mu/fluidic chip with integrated detection coil. It is also shown that a spectral resolution of 0.025 ppm is obtained when a microchannel with an arbitrary cross section is placed parallel to the magnetic field. A high SNR at low magnetic field for small volume samples is essential for the development of portable NMR systems where mini permanent magnets of 1 Tesla are used.
Item Type:Conference or Workshop Item
Copyright:© 2004 IEEE
Faculty:
Electrical Engineering, Mathematics and Computer Science (EEMCS)
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Link to this item:http://purl.utwente.nl/publications/47331
Official URL:http://dx.doi.org/10.1109/MEMS.2004.1290608
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