Neuronal adhesion and growth on polyethylenimine tracks microprinted on polyethyleneoxide-polypropyleneoxide coated surfaces


Share/Save/Bookmark

Ruardij, T.G. and Boogaart van den, M.A.F. and Rutten, W.L.C. (2002) Neuronal adhesion and growth on polyethylenimine tracks microprinted on polyethyleneoxide-polypropyleneoxide coated surfaces. In: Second joint IEEE-EMBS/BMES conference,[Engineering in Medicine and Biology, 2002. 24th Annual Conference and the Annual Fall Meeting of the Biomedical Engineering Society], Houston, USA.

[img]
Preview
PDF
323Kb
Abstract:Adsorbed layers of polyediylenoxide-polypropylenoxide (PEO-PPO) blockcopolymers were tested as neurophobic background coatings in neuronal patterning studies over a time period of 30 days. Microprinted tracks of polyethylenimine (PEI) were used as the neuron-adhesive part of the pattern. Results showed that PEO-PPO surfactants F108 and F127 (Synperonics, ICI) significantly reduced the growth of neuronal tissue when adsorbed on Polyimide and Fluorocarbon surfaces up till 8 days. Also survival of neuronal tissue was not negatively affected by the PEO-PPO. Viability of the cultures was assessed after 30 days and showed viability factors above 0.9 (scale 0 to 1).
Item Type:Conference or Workshop Item
Copyright:©2002 IEEE
Faculty:
Electrical Engineering, Mathematics and Computer Science (EEMCS)
Research Group:
Link to this item:http://purl.utwente.nl/publications/43912
Export this item as:BibTeX
EndNote
HTML Citation
Reference Manager

 

Repository Staff Only: item control page

Metis ID: 207689