Single molecule detection on the cell membrane with near-field scanning optical microscopy


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Bakker de, Bärbel Irene (2004) Single molecule detection on the cell membrane with near-field scanning optical microscopy. thesis.

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Abstract:In this research we have developed a dedicated near- field scanning optical microscope (NSOM) for molecular biology and applied it to study the spatial organization of (fluorescently labeled) proteins at the cell surface. For the first time, protein clusters and individual molecules are resolved at the cell membrane with nanometer resolution using an optical method
Item Type:Thesis
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Link to this item:http://purl.utwente.nl/publications/41416
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Metis ID: 218391