Monitoring Cerebral perfusion using near infrared spectroscopy and laser doppler flowmetry

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Klaessens, J.H.G.M. and Kolkman, R.G.M. and Hopman, J.C.W. and Hondebrink, E. and Liem, K.D. and Steenbergen, W. and Mul de, F.F.M. and Thijssen, J.M. (2003) Monitoring Cerebral perfusion using near infrared spectroscopy and laser doppler flowmetry. Physiological Measurement, 24 . N35-N40. ISSN 0967-3334

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Abstract:This paper describes the simultaneous use of two, noninvasive, near-infrared
techniques near-infrared spectroscopy (NIRS) and a continuous wave NIR laser
Doppler flow system (LDF) to measure changes in the blood oxygenation,
blood concentration and blood flow velocity in the brain. A piglet was used
as animal model. A controlled change in the arterial CO2 pressure (PaCO2)
was applied for achieving changes in the listed cerebrovascular parameters.
The time courses of blood concentration parameters (NIRS) and RMS blood
flow velocity (LDF) were found to correspond closely with those of carotid
blood flow and arterial carbon dioxide pressure (PaCO2). This result shows
the additional value of LDF when combined with NIRS, preferably in one
instrument. Development of pulsed LDF for regional blood flow measurement
is indicated.
Item Type:Article
Copyright:© Institute of Physics and IOP Publishing Limited 2003
Faculty:
Science and Technology (TNW)
Research Group:
Link to this item:http://purl.utwente.nl/publications/40564
Official URL:http://dx.doi.org/10.1088/0967-3334/24/4/N03
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Metis ID: 212525