The use of self-assembled receptor layers in immunosensors

Kooyman, R.P.H. and Heuvel van den, D.J. and Drijfhout, J.W. and Welling, G.W. (1994) The use of self-assembled receptor layers in immunosensors. Thin Solid Films, 244 (1-2). pp. 913-916. ISSN 0040-6090

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Abstract:	We demonstrate that a self-assembled monolayer consisting of an alkylthiol coupled synthetic peptide adsorbed to a gold substrate results in a sensitive receptor surface for specific recognition of protein molecules. The affinity constant of this binding is comparable with that of an antibody-antigen reaction. Evidence is found that such a receptor surface is capable of reversible binding.
Item Type:	Article
Copyright:	© 1994 Elsevier Science
Faculty:	Science and Technology (TNW)
Research Group:	Nano-Biophysics (NBP)
Link to this item:	http://purl.utwente.nl/publications/24658
Official URL:	http://dx.doi.org/10.1016/0040-6090(94)90599-1
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Metis ID: 129459